Search Results - "Rundle, C H"

Local administration of AAV-DJ pseudoserotype expressing COX2 provided early onset of transgene expression and promoted bone fracture healing in mice by Lakhan, R, Baylink, D J, Lau, K-H W, Tang, X, Sheng, M H-C, Rundle, C H, Qin, X

“…We have previously obtained compelling proof-of-principle evidence for COX2 gene therapy for fracture repair using integrating retroviral vectors. For this…”
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Genetic variation in bone-regenerative capacity among inbred strains of mice by Li, X, Gu, W, Masinde, G, Hamilton-Ulland, M, Rundle, C.H, Mohan, S, Baylink, D.J

“…Genetic variation in bone-regenerative capacity has not been studied in any animal model system. We developed a “drill-hole” model in the tail vertebra of…”
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In situ hybridization analysis of immunoglobulin heavy chain variable gene expression with family specific oligonucleotide probes by Rundle, Charles H., Schroeder, Harry W., Koopman, William J.

“…We have developed an improved in situ hybridization (ISH) technique for the analysis of human immunoglobulin heavy chain variable ( V H) gene family expression…”
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Immunoglobulin gene expression in rheumatoid arthritis by Bridges, Jr, S L, Koopman, W J, Lee, S K, Clausen, B E, Kirkham, P M, Rundle, C H, Schroeder, Jr, H W

“…Rheumatoid arthritis (RA) is characterized by inflammation of synovium, in which immunoglobulin-secreting plasma cells are generally present. The forces…”
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Transactivation of Hox gene expression in a VP16-dependent binary transgenic mouse system by Rundle, Charles H, Macias, MiMi P, Yueh, Y.Gloria, Gardner, David P, Kappen, Claudia

“…Mice with aberrant expression of Hox genes have provided valuable insight into the role of Hox class transcription factors in patterning the developing…”
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Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair by Rundle, Charles H., Wang, Hali, Yu, Hongrun, Chadwick, Robert B., Davis, Emile I., Wergedal, Jon E., Lau, K.-H. William, Mohan, Subburaman, Ryaby, James T., Baylink, David J.

“…Microarray analysis of gene expression was performed in the healing femur fractures of 13-week-old male rats during the inflammatory stage of repair, at 3 days…”
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In vivo bone formation in fracture repair induced by direct retroviral-based gene therapy with bone morphogenetic protein-4 by Rundle, Charles H, Miyakoshi, Naohisa, Kasukawa, Yuji, Chen, Shin-Tai, Sheng, Matilda H.-C, Wergedal, Jon E, Lau, K.-H.William, Baylink, David J

“…This study sought to develop an in vivo gene therapy to accelerate the repair of bone fractures. In vivo administration of an engineered viral vector to…”
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Bax deficiency in mice increases cartilage production during fracture repair through a mechanism involving increased chondrocyte proliferation without changes in apoptosis by Rundle, Charles H, Wang, Xiaoguang, Sheng, Matilda H.-C, Wergedal, Jon E, Lau, K.-H. William, Mohan, Subburaman

“…Abstract This study sought to determine the role of the pro-apoptotic gene, Bax, in fracture healing by comparing femoral fracture healing in Bax knockout (KO)…”
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Expression of the fibroblast growth factor receptor genes in fracture repair by Rundle, Charles H, Miyakoshi, Naohisa, Ramirez, Enrique, Wergedal, Jon E, Lau, K-H William, Baylink, David J

“…The spatial and temporal expression domains of the fibroblast growth factor receptor genes were examined in the healing rat femur fracture by in situ…”
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In situ hybridization analysis of immunoglobulin VH gene family expression in rheumatoid arthritis by Rundle, C H, Schroeder, Jr, H W, Koopman, W J

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Developmental expression of the murine Prl-1 protein tyrosine phosphatase gene by Rundle, Charles H., Kappen, Claudia

“…The expression of the murine Prl‐1 protein tyrosine phosphatase gene was examined in normal embryos from E10.5 through E18.5. Prl‐1 mRNA was detected in the…”
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