Search Results - "Rund, LA"

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein by Ackerman, Susan L, Kozak, Leslie P, Przyborski, Stefan A, Rund, Laurie A, Boyer, Bert B, Knowles, Barbara B

“…Migration of neurons from proliferative zones to their functional sites is fundamental to the normal development of the central nervous system. Mice homozygous…”
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CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation by Holler, P D, Lim, A R, Cho, B K, Rund, L A, Kranz, D M

“…T cells are activated by binding of the T cell receptor (TCR) to a peptide-major histocompatibility complex (MHC) complex (pMHC) expressed on the surface of…”
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Isolation and molecular characterization of the porcine transforming growth factor beta type I receptor ( TGFBR1) gene by Chen, Kefei, Rund, Laurie A., Beever, Jonathan E., Schook, Lawrence B.

“…The transforming growth factor beta (TGF beta) family is essential for normal growth and development of different organ systems. Here we describe the isolation…”
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Characterization of the porcine ATM gene: Towards the generation of a novel non-murine animal model for Ataxia-Telangiectasia by Rogatcheva, Margarita B., Fritz, Krista L., Rund, Laurie A., Pollock, Callie B., Beever, Jonathan E., Counter, Christopher M., Schook, Lawrence B.

“…Ataxia-Telangiectasia (A-T) is a genetic disorder causing cerebellar degeneration, immune deficiency, cancer predisposition, chromosomal instability and…”
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Genomics and clinical medicine: rationale for creating and effectively evaluating animal models by Swanson, Kelly S, Mazur, Meredith J, Vashisht, Kapil, Rund, Laurie A, Beever, Jonathan E, Counter, Christopher M, Schook, Lawrence B

“…Because resolving human complex diseases is difficult, appropriate biomedical models must be developed and validated. In the past, researchers have studied…”
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CD8 super(-) T Cell Transfectants that Express a High Affinity T Cell Receptor Exhibit Enhanced Peptide-dependent Activation by Holler, P D, Lim, A R, Cho, B K, Rund, LA, Kranz, D M

“…T cells are activated by binding of the T cell receptor (TCR) to a peptide-major histocompatibility complex (MHC) complex (pMHC) expressed on the surface of…”
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IL-12 Treatment of Endogenously Arising Murine Brain Tumors by Roy, Edward J, Gawlick, Ute, Orr, Brent A, Rund, Laurie A, Webb, Andrew G, Kranz, David M

“…A number of recent studies have indicated that T cells can be stimulated to attack transplanted brain tumors in rodent models. As IL-12 has been shown to…”
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Antigen recognition and allogeneic tumor rejection in CD8+ TCR transgenic/RAG(-/-) mice by Manning, TC, Rund, LA, Gruber, MM, Fallarino, F, Gajewski, TF, Kranz, DM

“…Three sources of help for the development of a CD8+ CTL response have been described: the CD4+ direct and indirect pathways and the CD8+ direct pathway. In an…”
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Bispecific agents target endogenous murine T cells against human tumor xenografts by Rund, Laurie A., Cho, Bryan K., Manning, Thomas C., Holler, Phillip D., Roy, Edward J., Kranz, David M.

“…A variety of immunological approaches to cancer treatment are currently being explored. These include strategies designed to enhance or redirect the activity…”
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Bispecific agents target endogenous murine T cells against human tumor xenografts by Rund, LA, Cho, B K, Manning, T C, Holler, P D, Roy, E J, Kranz, D M

“…A variety of immunological approaches to cancer treatment are currently being explored. These include strategies designed to enhance or redirect the activity…”
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Targeting T cells against brain tumors with a bispecific ligand‐antibody conjugate by Roy, Edward J., Cho, Bryan K., Rund, Laurie A., Patrick, Todd A., Kranz, David M.

“…High‐affinity receptors expressed on the surface of some tumors can be exploited by chemically conjugating the ligand for the receptor and an antibody against…”
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Antigen recognition and allogeneic tumor rejection in CD8 super(+) TCR transgenic/RAG super(-/-) mice by Manning, T C, Rund, LA, Gruber, M M, Fallarino, F, Gajewski, T F, Kranz, D M

“…Three sources of help for the development of a CD8 super(+) CTL response have been described: the CD4 super(+) direct and indirect pathways and the CD8…”
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Targeting tumor cells with bispecific antibodies and T cells by Kranz, D.M, Manning, T.C, Rund, L.A, Cho, B.K, Gruber, M.M, Roy, E.J

“…It has been known for some time that mammalian immune systems are capable of eliminating large tumor burdens. Redirecting the immune response of a patient to…”
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Harvesting the Genomic Promise: Recombineering Sequences for Phenotypes by Rogatcheva, Margarita B., Rund, Laurie A., Beever, Jonathan E., Schook, Lawrence B.

“…The past decade has witnessed the construction of linkage and physical maps defining quantitative trait loci (QTL) in various domesticated species. Targeted…”
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Regulation of insulin-like growth factor-I ribonucleic acid expression, polypeptide secretion, and binding protein activity by growth hormone in porcine preadipocyte cultures by Gaskins, H R, Kim, J W, Wright, J T, Rund, L A, Hausman, G J

“…Insulin-like growth factor-I (IGF-I) is a mitogenic polypeptide postulated to mediate the effect of GH on adipose tissue development. To determine if the…”
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Immunocytochemical localization of luteinizing hormone-releasing hormone and proopiomelanocortin neurons within the preoptic area and hypothalamus of the bovine brain by Leshin, L.S, Rund, L.A, Crim, J.W, Kiser, T.E

“…The anatomical locations of proopiomelanocortin (POMC) and luteinizing hormone-releasing hormone (LHRH) neurons were examined in brain tissue from peripubertal…”
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Distribution of beta-endorphin immunoreactivity in the arcuate nucleus and median eminence of postpartum anestrus and luteal phase cows by Leshin, L S, Rund, L A, Kraeling, R R, Crim, J W, Kiser, T E

“…Deficiency in the secretion of luteinizing hormone-releasing hormone (LHRH) from the median eminence (ME) is one of the factors limiting reinitiation of…”
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The bovine preoptic area and median eminence: sites of opioid inhibition of luteinizing hormone-releasing hormone secretion by Leshin, L.S. (USDA, ARS, Richard B. Russell Agric. Res. Center, Athens, GA), Rund, L.A, Kraeling, R.R, Kiser, T.E

“…Autoradiography was used to quantify opioid receptors in the median eminence (ME) and preoptic area (POA) of the brain of eight heifers, and in vitro…”
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Influence of the ovary and suckling on luteinizing hormone response to naloxone in postpartum beef cows by Rund, L.A. (University of Georgia, Athens), Leshin, L.S, Thompson, F.N, Rampacek, G.B, Kiser, T.E

“…The influence of the suckling stimulus and ovarian secretions on LH response to naloxone was studied in 16 postpartum anestrous beef cows that were assigned…”
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Failure of naloxone to stimulate luteinizing hormone secretion during pregnancy and steroid treatment of ovariectomized beef cows by RUND, L. A, THOMPSON, F. N, BYERLEY, D. J, KISER, T. E

“…The response of serum luteinizing hormone (LH) to naloxone, an opiate antagonist, and gonadotropin-releasing hormone (GnRH) was measured in cows in late…”
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