Search Results - "Run, Xiaoqin"

Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases by Yu, Yang, Run, Xiaoqin, Liang, Zhihou, Li, Yi, Liu, Fei, Liu, Ying, Iqbal, Khalid, Grundke-Iqbal, Inge, Gong, Cheng-Xin

“…Tau is a neuronal microtubule-associated protein. Its hyperphosphorylation plays a critical role in Alzheimer disease (AD). Expression and phosphorylation of…”
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Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain by Liu, Ying, Li, Xiaojing, Yu, Yang, Shi, Jianhua, Liang, Zhihou, Run, Xiaoqin, Li, Yi, Dai, Chun-ling, Grundke-Iqbal, Inge, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin

“…O-GlcNAcylation is a common posttranslational modification of nucleocytoplasmic proteins by β-N-acetylglucosamine (GlcNAc). The dynamic addition and removal of…”
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Single Hormone Receptor-Positive Metaplastic Breast Cancer: Similar Outcome as Triple-Negative Subtype by Mao, Jinqian, Hu, Jin, Zhang, Yanting, Shen, Jian, Dong, Fang, Zhang, Ximeng, Ming, Jie, Huang, Tao, Run, Xiaoqin

“…Metaplastic breast cancer (MBC) is a rare and aggressive subtype of the breast. To understand the characteristics and prognosis of single hormone…”
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Intranasal Insulin Prevents Anesthesia-induced Cognitive Impairments in Aged Mice by Li, Xing, Run, Xiaoqin, Wei, Zhen, Zeng, Kuan, Liang, Zhihou, Huang, Fang, Ke, Dan, Wang, Qun, Wang, Jian-Zhi, Liu, Rong, Zhang, Bin, Wang, Xiaochuan

“…Preclinical and clinical evidence suggests that elderly individuals are at increased risk of cognitive decline after general anesthesia. General anesthesia is…”
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Differential effects of an O-GlcNAcase inhibitor on tau phosphorylation by Yu, Yang, Zhang, Lan, Li, Xiaojing, Run, Xiaoqin, Liang, Zhihou, Li, Yi, Liu, Ying, Lee, Moon H, Grundke-Iqbal, Inge, Iqbal, Khalid, Vocadlo, David J, Liu, Fei, Gong, Cheng-Xin

“…Abnormal hyperphosphorylation of microtubule-associated protein tau plays a crucial role in neurodegeneration in Alzheimer's disease (AD). The aggregation of…”
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Temperature control can abolish anesthesia‐induced tau hyperphosphorylation and partly reverse anesthesia‐induced cognitive impairment in old mice by Xiao, Haibing, Run, Xiaoqin, Cao, Xu, Su, Ying, Sun, Zhou, Tian, Cheng, Sun, Shenggang, Liang, Zhihou

“…Aims Anesthesia is related to cognitive impairment and the risk for Alzheimer's disease. Hypothermia during anesthesia can lead to abnormal…”
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Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice by Chen, Yanxing, Run, Xiaoqin, Liang, Zhihou, Zhao, Yang, Dai, Chun-Ling, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin

“…It is well documented that elderly individuals are at increased risk of cognitive decline after anesthesia. General anesthesia is believed to be a risk factor…”
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Tau phosphorylation and μ-calpain activation mediate the dexamethasone-induced inhibition on the insulin-stimulated Akt phosphorylation by Liu, Yudong, Su, Ying, Sun, Shenggang, Wang, Tao, Qiao, Xian, Run, Xiaoqin, Liang, Zhihou

“…Evidence has suggested that insulin resistance (IR) or high levels of glucocorticoids (GCs) may be linked with the pathogenesis and/or progression of…”
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Development and validation of a prognostic nomogram model in primary cutaneous and subcutaneous soft tissue angiosarcoma by Mao, Jinqian, Hu, Jin, Chen, Yunfei, Li, Yiqing, Run, Xiaoqin

“…The current study aimed to investigate the prognosis and treatment of primary cutaneous angiosarcoma (PCA) and primary subcutaneous angiosarcoma (PSCA), and…”
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Intranasal insulin restores insulin signaling, increases synaptic proteins, and reduces Aβ level and microglia activation in the brains of 3xTg-AD mice by Chen, Yanxing, Zhao, Yang, Dai, Chun-ling, Liang, Zhihou, Run, Xiaoqin, Iqbal, Khalid, Liu, Fei, Gong, Cheng-Xin

“…Decreased brain insulin signaling has been found recently in Alzheimer's disease (AD). Intranasal administration of insulin, which delivers the drug directly…”
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Rapamycin decreases tau phosphorylation at Ser214 through regulation of cAMP-dependent kinase by Liu, Yudong, Su, Ying, Wang, Jiajia, Sun, Shenggang, Wang, Tao, Qiao, Xian, Run, Xiaoqin, Li, Hui, Liang, Zhihou

“…► We use two cell models to investigate how rapamycin regulates tau phosphorylation. ► Rapamycin induces regulation of PKA that is prevented by U0126. ► The…”
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Anesthesia induces phosphorylation of tau by Run, Xiaoqin, Liang, Zhihou, Zhang, Lan, Iqbal, Khalid, Grundke-Iqbal, Inge, Gong, Cheng-Xin

“…Abnormal hyperphosphorylation and aggregation of microtubule-associated protein tau play a crucial role in neurodegeneration of Alzheimer's disease (AD)…”
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Anesthetics and tau protein: animal model studies by Run, Xiaoqin, Liang, Zhihou, Gong, Cheng-Xin

“…Recent studies have suggested that general anesthesia may initiate or accelerate cognitive impairment and Alzheimer's disease (AD). To understand the possible…”
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Pretreatment of PC12 Cells with 17β-estradiol Prevents Aβ-Induced Down-Regulation of CREB Phosphorylation and Prolongs Inhibition of GSK-3β by Chen, Yanxing, Su, Ying, Run, Xiaoqin, Sun, Zhou, Wang, Tao, Sun, Shenggang, Liang, Zhihou

“…It is believed that estrogen protects neurons against various toxicities like that from amyloid β (Aβ) in Alzheimer’s disease (AD). In the present study, we…”
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P3‐034: Rapamycin downregulates tau phosphorylation in SH‐SY5Y cells by Liang, Zhihou, Liu, Yudong, Run, Xiaoqin, Su, Ying, Sun, Shenggang

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Rapamycin downregulates tau phosphorylation in SH-SY5Y cells by Liang, Zhihou, Liu, Yudong, Run, Xiaoqin, Su, Ying, Sun, Shenggang

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Tau Phosphorylation and [mu]-Calpain Activation Mediate the Dexamethasone-Induced Inhibition on the Insulin-Stimulated Akt Phosphorylation by Liu, Yudong, Su, Ying, Sun, Shenggang, Wang, Tao, Qiao, Xian, Run, Xiaoqin, Liang, Zhihou

“…Evidence has suggested that insulin resistance (IR) or high levels of glucocorticoids (GCs) may be linked with the pathogenesis and/or progression of…”
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Human Tau may Modify Glucocorticoids-Mediated Regulation of cAMP-dependent Kinase and Phosphorylated cAMP Response Element Binding Protein by Liu, Yudong, Su, Ying, Sun, Shenggang, Wang, Tao, Qiao, Xian, Li, Hui, Run, Xiaoqin, Liang, Zhihou

“…Phosphorylation of the cAMP response element binding protein (CREB) by cAMP-dependent kinase (PKA) is critical to memory formation. However, activation of PKA…”
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Pretreatment of PC12 Cells with 17[beta]-estradiol Prevents A[beta]-Induced Down-Regulation of CREB Phosphorylation and Prolongs Inhibition of GSK-3[beta] by Chen, Yanxing, Su, Ying, Run, Xiaoqin, Sun, Zhou, Wang, Tao, Sun, Shenggang, Liang, Zhihou

“…It is believed that estrogen protects neurons against various toxicities like that from amyloid [beta] (A[beta]) in Alzheimer's disease (AD). In the present…”
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An investigation into insulin on pCREB after treated by ADDLs by Run, Xiaoqin, Liu, Yudong, Su, Ying, Liang, Zhihou

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