Search Results - "Rumler, A"

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    Potential cardiotonic agents. 10. Synthesis and positive inotropic action of 5-(4-pyridinyl)- and 5-phenyl-substituted 2-alkylthio-3-cyan-pyridines and their S-oxidation products by Rumler, A, Hagen, V, Hagen, A

    Published in Pharmazie (01-09-1990)
    “…The alkylation of the 5-(4-pyridinyl)- and 5-phenyl-substituted 3-cyan-2(1H)-pyridinethiones 1 with alkyl iodides and halomethylcarbonyl compounds led to the…”
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    Potential cardiotonic agents. 8. 2-acyloxyalkylamino-, 2-acyloxyalkoxy-, and 2-acylaminoalkylamino-3-cyan-5-(pyrid-4-yl) pyridine by Hagen, V, Klauschenz, E, Rumler, A, Niedrich, H, Hagen, A, Heer, S, Mitzner, R

    Published in Pharmazie (01-05-1990)
    “…By acylation of our previously described cardiotonic active 2-hydroxyalkylamino, 2-hydroxyalkoxy, 2-aminoalkyl-amino and 2-piperazino substituted…”
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    Potential cardiotonics. 7. Synthesis and cardiovascular effects of 5-(4-pyridinyl)-, 6-methyl-4-(4-pyridinyl) and 6-methyl-5-phenyl-substituted 3-cyano-2-aminoalkylamino-pyridines by Hagen, V, Rumler, A, Klauschenz, E, Hagen, A, Heer, S, Faust, G, Mitzner, R

    Published in Pharmazie (01-04-1990)
    “…The title compounds were synthesized by treating of 2-chloro-pyridines 1-3 with the appropriate aminoalkylamines or piperazines. In isolated guinea pig atria…”
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    Potential cardiotonic agents. 6. Synthesis and cardiovascular properties of 5-(4-pyridinyl)-, 6-methyl-5-(4-pyridinyl)- and 6-methyl-5-phenyl-substituted 3-cyano-2-oxaalkyoxy-pyridines by Hagen, V, Klauschenz, E, Rumler, A, Hagen, A, Heer, S, Mitzner, R, Niedrich, H, Lohmann, D

    Published in Pharmazie (01-03-1990)
    “…The headline compounds were prepared by the reaction of 2-chloropyridines 1-3 with the appropriate alcohols in presence of potassium hydroxide and the sodium…”
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    Potential cardiotonic agents. 4. Synthesis, cardiovascular activity, molecular and crystal structure of 5-phenyl- and 4-(4-pyridinyl)-substituted 2(1H)-pyridinethiones by Hagen, V, Rumler, A, Reck, G, Hagen, A, Labes, D, Heer, S

    Published in Pharmazie (01-12-1989)
    “…Cyclisation of the vinylogous amidinium salt 1 or the 4-ethoxy- and 4-morpholino-3-butene-2-ones, respectively, 4 and 6 with cyano-thioacetamide yielded the…”
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    Potential cardiotonic agents. 2. Synthesis and pharmacologic properties of 5-(pyri-4-yl)- and 5-phenyl substituted 3-cyano-6-methyl-2-oxaalkylaminopyridines by Klauschenz, E, Rumler, A, Hagen, V, Hagen, A, Heer, S, Mitzner, R, Niedrich, H

    Published in Pharmazie (01-01-1989)
    “…The authors describe the preparation, the physicochemical properties and the results of evaluation of positive inotropic and vasodilator activities in a series…”
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