Search Results - "Rumbero Sánchez, Ángel"
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1
Isolation of Nocuolin A and Synthesis of New Oxadiazine Derivatives. Design, Synthesis, Molecular Docking, Apoptotic Evaluation, and Cathepsin B Inhibition
Published in Marine drugs (29-04-2023)“…Nocuolin A ( ), an oxadiazine, was isolated from the cyanobacterium sp. Its chemical structure was elucidated using NMR and mass spectroscopic data. From this…”
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2
Study of Pentacyclic Triterpenes from Lyophilised Aguaje: Anti-Inflammatory and Antioxidant Properties
Published in International journal of molecular sciences (05-09-2024)“…, commonly known as Aguaje or Moriche palm, is traditionally recognised in South America for its medicinal properties, particularly for its anti-inflammatory…”
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3
Cybastacines A and B: Antibiotic Sesterterpenes from a Nostoc sp. Cyanobacterium
Published in Journal of natural products (Washington, D.C.) (23-02-2018)“…Cybastacines A (1) and B (2) were discovered as a novel pentacyclic sesterterpenoid–alkaloid skeleton structure, with a guanidinium group. These molecules were…”
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4
Novel 1,2,4-oxadiazole compounds as PPAR-α ligand agonists: a new strategy for the design of antitumour compounds
Published in RSC medicinal chemistry (20-07-2023)“…Modulation of PPAR-α by natural ligands is a novel strategy for the development of anticancer therapies. A series of 16 compounds based on the structure of…”
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5
Synthesis and biological screening of a library of macamides as TNF-α inhibitors
Published in RSC medicinal chemistry (01-10-2020)“…Thirty-five macamide analogues were synthesised by modifying the initial molecular structure. The resulting structures were confirmed using NMR and MS…”
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6
Identification of TRPV1 Ion Channels Agonists of Tropaeolum tuberosum in Human Skin Keratinocytes
Published in Planta medica (01-04-2021)“…commonly known as Mashua, is an herbal remedy used in traditional Andean medicine for the relief of kidney and bladder pain, as well as contusions. This study…”
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Anti-inflammatory effects of TNF-α and ASK1 inhibitory compounds isolated from Schkuhria pinnata used for the treatment of dermatitis
Published in Journal of ethnopharmacology (10-01-2024)“…The Andean Schkuhria pinnata species commonly known as ‘Canchalagua’ is used as an infusion in Andean countries to treat various anti-inflammatory and…”
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Synthesis and biological screening of a library of macamides as TNF-α inhibitors† †Electronic supplementary information (ESI) available: 1H- and 13C- NMR spectra of the synthetic macamides analysed in this study are provided as supporting information (Fig. 1S–70S). See DOI: 10.1039/d0md00208a
Published in RSC medicinal chemistry (06-08-2020)“…Thirty-five macamide analogues were synthesised by modifying the initial molecular structure. Thirty-five macamide analogues were synthesised by modifying the…”
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9
Hydroalcoholic extract of Tagetes minuta L. inhibits inflammatory bowel disease through the activity of pheophytins on the NF-κB signalling pathway
Published in Journal of ethnopharmacology (25-03-2021)“…Species of the genus Tagetes are well known for their anti-inflammatory properties. Tagetes minuta “Huacatay” is an endemic species of South America that has…”
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10
Alkaloids isolated from Tropaeolum tuberosum with cytotoxic activity and apoptotic capacity in tumour cell lines
Published in Phytochemistry (Oxford) (01-09-2020)“…Two alkaloids were isolated and identified for the first time in the black tubers of Tropaeolum tuberosum, collected from the Titicani-Taca, Ingavi province in…”
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11
Diterpenes of Pinus pinaster aiton with anti-inflammatory, analgesic, and antibacterial activities
Published in Journal of ethnopharmacology (10-01-2024)“…The P. pinaster species, known as ‘Pino nigral or rodeno’, is used in the treatment of colds, asthma, flu, and tuberculosis. This study determined the…”
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12
Design, Synthesis and Pharmacological Evaluation of N‐Benzyl Linoleamide Analogues from Tropaeolum tuberosum as NF‐κB Inhibitors and Nrf2 Activators
Published in ChemistrySelect (Weinheim) (15-10-2020)“…Nineteen N‐benzyl linoleamide analogues (macamide from Tropaeolum tuberosum) were synthesised, modifying the molecular structure (benzyl position, aromatic…”
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13
Antitumoral activity of 1,2,4-oxadiazoles compounds isolated from the Neowerdermannia vorwerkii in liver and colon human cancer cells
Published in Phytochemistry (Oxford) (01-09-2022)“…Two unknown 1,2,4-oxadiazoles (3-(pyridin-3-yl)-5-(thiophen-3-yl)-1,2,4-oxadiazole and 5-(3-hydroxyphenyl)-3-(pyridin-3-yl)-1,2,4-oxadiazole) and one known…”
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14
Inhibition of melanin production and tyrosinase activity by flavonoids isolated from Loranthus acutifolius
Published in Natural product research (18-11-2021)“…Activity-guided fractionations of leaves and stems from Loranthus acutifolius led to the isolation of 2',4',6-trimethoxyflavone (1),…”
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15
Anti-inflammatory properties of Neowerdermannia vorwerkii Frič ‘Achacana’ used in treating stomach-related ailments
Published in Journal of ethnopharmacology (28-06-2022)“…The tuber of Neowerdermannia vorwerkii commonly known as ‘Achacana’ is used as an infusion in Andean countries to treat various gastrointestinal ailments,…”
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16
Spectroscopical Analysis of Andean Plant Species with Anti-inflammatory, Antioxidant, and Antibacterial Activities
Published in Revista brasileira de farmacognosia (01-02-2024)“…Achyrocline satureioides (Lam.) DC., Asteraceae, Clinopodium bolivianum Kuntze, Lamiaceae, Rubus urticifolius Poir., Rosaceae, and Tagetes elliptica Sm.,…”
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17
Triterpenoids isolated from Jatropha macrantha (Müll. Arg.) inhibit the NF-κB and HIF-1α pathways in tumour cells
Published in Natural product research (17-12-2021)“…Activity-guided fractionations of Müll. Arg. led to the isolation of pomolic acid ( ) and euscaphic acid ( ). The potential for inhibition against NF-κB and…”
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Antimicrobial compounds isolated from Tropaeolum tuberosum
Published in Natural product research (18-11-2021)“…Activity-guided fractionations of black tubers of Tropaeolum tuberosum led to the isolation of 3-[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl] benzonitrile (1) and…”
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19
Antitumoral potential of carbamidocyclophanes and carbamidocylindrofridin A isolated from the cyanobacterium Cylindrospermum stagnale BEA 0605B
Published in Phytochemistry (Oxford) (01-12-2020)“…Three carbamidocyclophanes, A, F and V, and carbamidocylindrofridin A were isolated from the cultured freshwater cyanobacterium Cylindrospermum stagnale,…”
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20
Alkaloids of Gnaphalium polycaulon with Anti-Alzheimer’s Activity
Published in Revista brasileira de farmacognosia (01-02-2022)“…Three alkaloids were isolated from the aerial parts of Gnaphalium polycaulon Pers., Asteraceae, collected from San Juan Huancollo, Ingavi Province, La Paz,…”
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