Search Results - "Rullmann, Ton"
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Identification of CXCL13 as a marker for rheumatoid arthritis outcome using an in silico model of the rheumatic joint
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-05-2011)“…Objective Rheumatoid arthritis (RA) is characterized by inflammation and joint destruction, with the degree of damage varying greatly among patients…”
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CoPub Mapper: mining MEDLINE based on search term co-publication
Published in BMC bioinformatics (11-03-2005)“…High throughput microarray analyses result in many differentially expressed genes that are potentially responsible for the biological process of interest. In…”
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Identification of new biomarker candidates for glucocorticoid induced insulin resistance using literature mining
Published in BioData mining (04-02-2013)“…Glucocorticoids are potent anti-inflammatory agents used for the treatment of diseases such as rheumatoid arthritis, asthma, inflammatory bowel disease and…”
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Target validation in silico: does the virtual patient cure the pharma pipeline?
Published in Expert opinion on therapeutic targets (01-10-2006)“…Genomics has multiplied the number of targets for new therapeutic interventions, but this has not yet lead to a marked increase of pharma pipeline outputs. The…”
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Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling
Published in Genome medicine (30-11-2012)“…Glucocorticoids, such as prednisolone, are widely used anti-inflammatory drugs, but therapy is hampered by a broad range of metabolic side effects including…”
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Completeness of NOEs in protein structures: A statistical analysis of NMR data
Published in Journal of biomolecular NMR (01-06-1999)“…The completeness of experimentally observed NOE restraints of a set of 97 NMR protein structures deposited in the PDB has been assessed. Completeness is…”
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