Search Results - "Rule, GS"

The Crystal Structure of a Major Dust Mite Allergen Der p 2, and its Biological Implications by Derewenda, U., Li, J., Derewenda, Z., Dauter, Z., Mueller, G.A., Rule, G.S., Benjamin, D.C.

“…The crystal structure of the common house mite ( Dermatophagoides sp.) Der p 2 allergen was solved at 2.15 Å resolution using the MAD phasing technique, and…”
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Glutathione Induces Helical Formation in the Carboxy Terminus of Human Glutathione Transferase A1-1 by Zhan, Yiping, Rule, Gordon S

“…The structure and dynamic properties of the C-terminal region of the human class alpha glutathione transferase A1-1 have been investigated with high-resolution…”
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MONTE: An automated Monte Carlo based approach to nuclear magnetic resonance assignment of proteins by Hitchens, T Kevin, Lukin, Jonathan A, Zhan, Yiping, McCallum, Scott A, Rule, Gordon S

“…A general-purpose Monte Carlo assignment program has been developed to aid in the assignment of NMR resonances from proteins. By virtue of its flexible data…”
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Hydrogen Exchange Nuclear Magnetic Resonance Spectroscopy Mapping of Antibody Epitopes on the House Dust Mite Allergen Der p 2 by Mueller, Geoffrey A., Smith, Alisa M., Chapman, Martin D., Rule, Gordon S., Benjamin, David C.

“…New strategies for allergen-specific immunotherapy have focused on reducing IgE reactivity of purified recombinant allergens while maintaining T-cell epitopes…”
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Stable Triplet of Uracil−Uracil Basepairs in a Small Antisense RNA by Zhan, Yiping, Rule, Gordon S

“…The interaction between ant (antirepressor) mRNA and its antisense RNA, sar (small antisense RNA), is important in regulation of the development of…”
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Tertiary Structure of the Major House Dust Mite Allergen Der p 2:  Sequential and Structural Homologies by Mueller, Geoffrey A, Benjamin, David C, Rule, Gordon S

“…Sensitization to indoor allergens, especially those of the house dust mite, is strongly correlated with the development of asthma. We report the tertiary…”
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Determination of carbofuran by online immunoaffinity chromatography with coupled-column liquid chromatography/mass spectrometry by Rule, Geoffrey S, Mordehai, Alexander V, Henion, Jack

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Disorder-to-Order Transition of the Active Site of Human Class Pi Glutathione Transferase, GST P1-1 by Hitchens, T. Kevin, Mannervik, Bengt, Rule, Gordon S

“…Glutathione transferases comprise a large family of cellular detoxification enzymes that function by catalyzing the conjugation of glutathione (GSH) to…”
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Ligand-Induced Changes in the Structure and Dynamics of a Human Class Mu Glutathione S-Transferase by McCallum, Scott A, Hitchens, T. Kevin, Torborg, Christine, Rule, Gordon S

“…Glutathione transferases are detoxification enzymes that catalyze the addition of glutathione (GSH) to a wide variety of hydrophobic compounds. Although this…”
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Validation and application of an automated 96-well solid-phase extraction liquid chromatography–tandem mass spectrometry method for the quantitative determination of SCH 201781 in human plasma by Yang, Liyu, Wu, Ning, Rule, Geoffrey S., Campbell, Dale A., Perkins, John R., Rudewicz, Patrick J.

“…SCH 201781 is a direct thrombin inhibitor recently under study in clinical trials to determine its safety and efficacy for the treatment of venous and arterial…”
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Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity by Raghunathan, S, Chandross, R J, Kretsinger, R H, Allison, T J, Penington, C J, Rule, G S

“…The structures of three crystal forms of the class mu human glutathione transferase GSTM2-2 have been determined. X-ray phase information was obtained…”
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Global Changes in Amide Hydrogen Exchange Rates for a Protein Antigen in Complex with Three Different Antibodies by Williams Jr, David C., Benjamin, David C., Poljak, Roberto J., Rule, Gordon S.

“…The binding of anti-lysozyme monoclonal antibodies, D44.1 or D1.3, to their antigen reduces the rate of exchange for many amide hydrogens in lysozyme. The…”
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Expression and Secondary Structure Determination by NMR Methods of the Major House Dust Mite Allergen Der p 2 by Mueller, Geoffrey A., Smith, Alisa M., Williams, David C., Hakkaart, Gerrit A.J., Aalberse, Rob C., Chapman, Martin D., Rule, Gordon S., Benjamin, David C.

“…There exists a strong correlation between asthma and sensitization to indoor allergens. This study reports on the secondary structure of the major house dust…”
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Solution structure of the carboxyl terminus of a human class Mu glutathione S-transferase: NMR assignment strategies in large proteins by McCallum, S A, Hitchens, T K, Rule, G S

“…Strategies to obtain the NMR assignments for the HN, N, CO, Calpha and Cbeta resonance frequencies for the human class mu glutathione-S-transferase GSTM2-2 are…”
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Data requirements for reliable chemical shift assignments in deuterated proteins by Hitchens, T Kevin, McCallum, Scott A, Rule, Gordon S

“…The information required for chemical shift assignments in large deuterated proteins was investigated using a Monte Carlo approach (Hitchens et al., 2002). In…”
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Rapid method for visual identification of specific DNA sequences based on DNA-tagged liposomes by Rule, GS, Montagna, RA, Durst, RA

“…We describe a rapid method for visually determining specific DNA sequences at femtomole concentrations. Liposomes, encapsulating a red dye and labeled with…”
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Characteristics of DNA-Tagged Liposomes Allowing Their Use in Capillary-Migration, Sandwich-Hybridization Assays by Rule, Geoffrey S., Montagna, Richard A., Durst, Richard A.

“…Liposomes that have been labeled externally with a DNA oligomer are used in a capillary-migration, sandwich-hybridization assay for specific DNA target…”
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Reduction in the amide hydrogen exchange rates of an anti-lysozyme Fv fragment due to formation of the Fv-Lysozyme complex by Williams, David C, Rule, Gordon S, Poljak, Roberto J, Benjamin, David C

“…The Fv fragment of the monoclonal antibody D1.3 was expressed in bacteria. Standard triple resonance techniques were used to obtain the NMR resonance…”
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Effect of Deuteration on the Accuracy of HN–HN Distance Constraints by Briercheck, Deborah M., Rule, Gordon S.

“…The effect of deuteration on the measurement of HN–HN distances in moderately sized (15 kDa) proteins is discussed. Data are presented for a 15 kDa protein…”
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Cloning, Expression, and Characterization of a Class-Mu Glutathione Transferase from Human Muscle, the Product of the GST4 Locus by Vorachek, William R., Pearson, William R., Rule, Gordon S.

“…A class-mu glutathione transferase cDNA clone, GTHMUS, was isolated from human myoblasts and its sequence was determined. The sequence predicts a protein of…”
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