Search Results - "Rukavishnikov, Aleksey"
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Nanoscale 1,3,5,7-Tetrasubstituted Adamantanes and p-Substituted Tetraphenyl-methanes for AFM Applications
Published in Organic letters (17-10-2002)“…Tetrahedrally shaped nanoscale molecules 18−20 were synthesized from the corresponding tetraiodide by a series of Sonogashira coupling reactions. Three of the…”
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Nanoscale Tripodal 1,3,5,7-Tetrasubstituted Adamantanes for AFM Applications
Published in Journal of organic chemistry (13-06-2003)“…The synthesis of four novel nanoscale 1,3,5,7-tetrasubstituted adamantanes 22 and 25−27 designed for atomic force microscopy (AFM) applications is described…”
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Synthesis of Well-Defined Tower-Shaped 1,3,5-Trisubstituted Adamantanes Incorporating a Macrocyclic Trilactam Ring System
Published in Journal of organic chemistry (20-02-2004)“…We describe the synthesis of two novel well-defined tower-shaped 1,3,5-trisubstituted adamantanes 30 and 33 that incorporate a macrocyclic trilactam ring…”
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Evaluation of granulocyte phagocytic activity using pHrodo™ dye, a novel fluorogenic pH indicator
Published in The FASEB journal (01-04-2008)“…Phagocytosis is an essential host defense performed by, among others, granulocytes and monocytes. We demonstrate a novel fluorogenic approach to distinguish…”
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Allosteric Interactions within Subsites of a Monomeric Enzyme: Kinetics of Fluorogenic Substrates of PI-Specific Phospholipase C
Published in Biophysical journal (01-05-2003)“…Two novel water-soluble fluorescein myo-inositol phosphate (FLIP) substrates, butyl-FLIP and methyl-FLIP, were used to examine the kinetics and subsite…”
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New Ca2+ fluoroionophores based on the BODIPY fluorophore
Published in Combinatorial chemistry & high throughput screening (01-06-2003)“…Calcium (Ca(2+)) fluoroionophores are useful in cell-based functional assays of G-protein coupled receptor (GPCR) activation or ion channel modulation. In this…”
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Synthesis of Fluorogenic Substrates for Continuous Assay of Phosphatidylinositol-Specific Phospholipase C
Published in Bioconjugate chemistry (01-03-2001)“…An improved synthesis of fluorogenic substrate analogues for phosphatidylinositol-specific phospholipase C (PI-PLC) is described. The water-soluble substrates,…”
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Fluorogenic cephalosporin substrates for β-lactamase TEM-1
Published in Analytical biochemistry (01-12-2011)“…Cephalosporin was used to synthesize soluble and precipitating fluorogenic β-lactam substrates that demonstrated differential catalytic hydrolysis by three…”
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Abstract 5098: GFP compatibility with EdU cell proliferation assay
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Abstract Examining cell proliferation in GFP expressing cells is of general interest in many aspects of biology including regenerative medicine, stem cells,…”
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A tower-shaped prototypic molecule designed as an atomically sharp tip for AFM applications
Published in Tetrahedron letters (27-08-1999)“…The synthesis of macrocycle 1 using a series of Sonogashira coupling reactions is described. This tower-shaped prototypic molecule tapers to a single hydrogen…”
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A CHROMOGENIC SUBSTRATE FOR THE CONTINUOUS ASSAY OF MAMMALIAN PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C
Published in Bioorganic & medicinal chemistry letters (20-05-1997)“…The synthesis of a chromogenic substrate for mammalian PI-PLC, d,l- myo-inositol 4,5-bis(dihydrogen phosphate) 1-(4-nitrophenyl hydrogen phosphate) tetrasodium…”
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Abstract 4033: Gene expression of EdU proliferating cells made possible with improved click chemistry
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Gene expression profiling of cancer cells has become increasingly common over the past five years. Especially important is identifying changes in gene…”
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Allosteric interactions within subsites of a monomeric enzyme: Kinetics of fluorogenic substrates of Pl-specific phospholipase C
Published in Biophysical journal (01-05-2003)“…Two novel water-soluble fluorescein myo-inositol phosphate (FLIP) substrates, butyl-FLIP and methyl-FLIP, were used to examine the kinetics and subsite…”
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Synthesis of a new fluorogenic substrate for the assay of phosphoinositide-specific phospholipase C
Published in Tetrahedron letters (10-09-1998)“…The synthesis of a fluorescein-derived fluorogenic substrate, D,L- myo-inositol l-([6′-hexyloxy-3-oxo]spiro[isobenzofuran-1(3 H),9′-[9 H]xanthen]-3′-yl…”
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Synthesis of a new fluorogenic substrate for the continuous assay of mammalian phosphoinositide-specific phospholipase C
Published in Bioorganic & medicinal chemistry letters (19-04-1999)“…The synthesis of a fluorogenic substrate for mammalian phosphoinositide-specific phospholipase C is described. The substrate, based on the widely used…”
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Improved synthesis of myo-inositol 1-(4-nitrophenyl hydrogen phosphate), a chromogenic substrate for phosphatidylinositol-specific phospholipase C
Published in Chemistry and physics of lipids (22-10-1997)“…This paper describes an improved procedure for the synthesis of racemic myo-inositol 1-(4-nitrophenyl hydrogen phosphate) (NPIP) a useful substrate for the…”
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