Search Results - "Ruiz Sánchez, Antonio"
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Decentralizing science: Towards an interoperable open peer review ecosystem using blockchain
Published in Information processing & management (01-11-2021)“…Scientific publication and its Peer Review system strongly rely on a few major industry players controlling most journals (e.g. Elsevier), databases (e.g…”
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Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor
Published in Angewandte Chemie International Edition (01-08-2022)“…A short total synthesis of tunicamycin V (1), a non‐selective phosphotransferase inhibitor, is achieved via a Büchner–Curtius–Schlotterbeck type reaction…”
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Randomized Phase III Trial of Trastuzumab Plus Capecitabine With or Without Pertuzumab in Patients With Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer Who Experienced Disease Progression During or After Trastuzumab-Based Therapy
Published in Journal of clinical oncology (10-09-2017)“…Purpose To assess the efficacy and safety of trastuzumab plus capecitabine with or without pertuzumab in patients with human epidermal growth factor receptor…”
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4
Shedding Light on the Origin of Solid‐State Luminescence Enhancement in Butterfly Molecules
Published in Chemistry : a European journal (02-11-2020)“…Different molecular strategies have been carefully evaluated to produce solid‐state luminescence enhancement (SLE) in compounds that show dark states in…”
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Clinical approach for managing patients with unexpected CDH1 mutations: A case report
Published in Molecular genetics & genomic medicine (01-07-2024)“…Hereditary diffuse gastric cancer (HDGC) (OMIM# 137215) is an autosomal dominant cancer syndrome associated with CDH1 (OMIM# 192090) mutations. Prophylactic…”
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Exploring the Ring-Closing Metathesis for the Construction of the Solomonamide Macrocyclic Core: Identification of Bioactive Precursors
Published in Journal of organic chemistry (18-05-2018)“…New synthetic strategies directed toward the novel cyclopeptides solomonamides have been explored utilizing an olefin metathesis as the key reaction. In the…”
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Nanostructuration Effect of Carbon‐Based Phenylene Vinylene Conjugated Porous Polymers on TiO2 Hybrid Materials for Artificial Photosynthesis
Published in Small structures (01-03-2024)“…This work examines the role of polymer nanostructuration of phenylene vinylene (PV) conjugated porous polymers (PV‐CPPs) as highly active photocatalysts for…”
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The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways
Published in PloS one (06-01-2011)“…Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are…”
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A Highly Stereoselective Synthesis of Glycidic Amides Based on a New Class of Chiral Sulfonium Salts: Applications in Asymmetric Synthesis
Published in Chemistry : a European journal (19-11-2012)“…A new type of chiral sulfonium salts that are characterized by a bicyclic system has been designed and synthesized from α‐amino acids. Their corresponding…”
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Epi-, Epoxy‑, and C2-Modified Bengamides: Synthesis and Biological Evaluation
Published in Journal of organic chemistry (07-06-2013)“…With the objective of investigating the influence of structural modifications of the polyketide chain of the bengamides upon their antitumoral activities, we…”
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Reversal of a Fluorescent Fluoride Chemosensor from Turn-Off to Turn-On Based on Aggregation Induced Emission Properties
Published in ACS sensors (28-01-2022)“…Here we present a new approach for the development of fluoride chemosensors taking advantage of aggregation induced emission (AIE) properties. Although…”
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Chiral Sulfur Ylides for the Synthesis of Bengamide E and Analogues
Published in Journal of organic chemistry (20-08-2010)“…A new synthetic methodology of asymmetric epoxidation developed in our laboratories has been employed for the stereoselective synthesis of bengamide E (16) and…”
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Exploring the Reactivity of Chiral Glycidic Amides for Their Applications in Synthesis of Bioactive Compounds
Published in European journal of organic chemistry (01-06-2014)“…A new class of chiral sulfonium salts, derived from L‐ and D‐methionine, has been designed and successfully employed in our laboratories for the…”
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An Array of Bengamide E Analogues Modified at the Terminal Olefinic Position: Synthesis and Antitumor Properties
Published in ChemMedChem (01-05-2013)“…Based on our previously described synthetic strategy for bengamide E, a natural product of marine origin with antitumor activity, a small library of analogues…”
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Chemistry and biology of cyclic depsipeptides of medicinal and biological interest
Published in Current medicinal chemistry (01-05-2004)“…Cyclodepsipeptides comprise a wide variety of cyclic peptides of natural origin and are characterized by the occurrence of at least one ester linkage. The…”
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Magnetic graphene molecularly imprinted polypyrrole polymer (MGO@MIPy) for electrochemical sensing of malondialdehyde in serum samples
Published in Microchemical journal (01-07-2022)“…[Display omitted] •Synthesis and characterization of a novel imprinted magnetic nanomaterial (MGO@MIPy).•MGO@MIPy was applied for the electrochemical…”
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Design of large Stokes shift fluorescent ortho-bis-styrylbenzenes. Optical characterization and fluoride sensing in logical gates
Published in Dyes and pigments (01-06-2024)“…This study combines underexplored fluorescent structures with large Stokes shifts, such as ortho-derivatives of bis(styryl)benzenes, for detecting three anions…”
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Enhancement of emission by surfactant-induced aggregation in poly(phenylenevinylene)-based lipochromophores
Published in Dyes and pigments (01-08-2020)“…A study has been carried out on the surfactochromicity of four new highly lipophilic poly(phenylenevinylene) (PPV) chromophores. Micellar encapsulation by a…”
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Metabolic oxidation regulates embryonic stem cell differentiation
Published in Nature Chemical Biology (01-06-2010)“…Metabolomics analysis of stem cells and differentiated cells points to chemical unsaturation as a key feature of stem cell metabolites. Manipulation of these…”
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Tuning of type-I and type-II mechanisms for visible light degradation in tris(styryl)benzene-sensitized TiO2 nanoparticles
Published in Dyes and pigments (01-01-2021)“…The visible light activation of TiO2 have been carried out by sensitization method using robust and metal-free tris(styryl)benzene (TSB) compounds as efficient…”
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