Search Results - "Ruiz García, Yara"

Untapped Opportunities of Resin‐to‐Resin Transfer Reactions (RRTR) for the Convergent Assembly of Multivalent Peptide Conjugates by Verzele, Dieter, Ruiz García, Yara, Madder, Annemieke

“…Handling of the individual fragments remains a bottleneck in the convergent assembly of peptides. Overlooked since the emergence of ligation chemistries during…”
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Looking beyond meningococcal B with the 4CMenB vaccine: the Neisseria effect by Ruiz García, Yara, Sohn, Woo-Yun, Seib, Kate L., Taha, Muhamed-Kheir, Vázquez, Julio A., de Lemos, Ana Paula S., Vadivelu, Kumaran, Pizza, Mariagrazia, Rappuoli, Rino, Bekkat-Berkani, Rafik

“…Infections with Neisseria meningitidis and Neisseria gonorrhoeae have different clinical manifestations, but the bacteria share up to 80–90% genome sequence…”
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Reduced reactogenicity of primary vaccination with DT3aP-HBV-IPV/Hib compared with DT2aP-HBV-IPV-Hib among infants: Mathematical projections in six countries by George, Marina, Pérez Martin, Jaime, AbdelGhany, Mohammad, Gkalapi, Foteini, Jamet, Nicolas, Kosse, Richelle C., Ruiz García, Yara, Turriani, Elisa, Berlaimont, Valérie

“…The hexavalent vaccines DT3aP-HBV-IPV/Hib and DT2aP-HBV-IPV-Hib are routinely used for primary immunization of infants against diphtheria, tetanus, pertussis,…”
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Specific dsDNA recognition by a mimic of the DNA binding domain of the c-Myc/Max transcription factor by Ruiz García, Yara, Pabon-Martinez, Y Vladimir, Smith, C I Edvard, Madder, Annemieke

“…We here report on the synthesis of the first mimic of the DNA binding domain of the c-Myc/Max-bHLH-ZIP transcription factor able to selectively recognize its…”
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Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake by Iyer, Abhishek, Van Lysebetten, Dorien, Ruiz García, Yara, Louage, Benoit, De Geest, Bruno G, Madder, Annemieke

“…The basic DNA recognition region of the GCN4 protein comprising 23 amino acids has been modified to contain two optimally positioned cysteines which have been…”
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immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies by Sanders, Melanie, Guo, Yirong, Iyer, Abhishek, Ruiz García, Yara, Galvita, Anastasia, Heyerick, Arne, Deforce, Dieter, Risseeuw, Martijn D.P, Van Calenbergh, Serge, Bracke, Marc, Eremin, Sergei, Madder, Annemieke, De Saeger, Sarah

“…An immunogen synthesis strategy was designed to develop anti-deoxynivalenol (DON) monoclonal antibodies with low cross-reactivity against structurally similar…”
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Urgent Need to Understand and Prevent Gonococcal Infection: From the Laboratory to Real-World Context by Ruiz García, Yara, Marrazzo, Jeanne, Martinón-Torres, Federico, Workowski, Kimberly, Giordano, Giulia, Pizza, Mariagrazia, Sohn, Woo-Yun

“…Neisseria gonorrhoeae is widespread globally. Primary prevention is unsuccessful and antimicrobial resistance threatens optimal management. There is no…”
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Water-soluble NHC-Cu catalysts: applications in click chemistry, bioconjugation and mechanistic analysis by Díaz Velázquez, Heriberto, Ruiz García, Yara, Vandichel, Matthias, Madder, Annemieke, Verpoort, Francis

“…Copper(I)-catalyzed 1,3-dipolar cycloaddition of azides and terminal alkynes (CuAAC), better known as "click" reaction, has triggered the use of…”
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Pandemic's influence on parents' attitudes and behaviors toward meningococcal vaccination by Tan, Litjen (L.J), Safadi, Marco Aurelio P., Horn, Michael, Regojo Balboa, Cristina, Moya, Elena, Schanbaum, Jamie, Pimenta, Pedro, Lambert, Emma, Soumahoro, Lamine, Sohn, Woo-Yun, Bruce, Teresa, Ruiz García, Yara

“…Invasive meningococcal disease is a life-threatening infection preventable through vaccination. Pediatric vaccination rates have declined during the…”
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Cyclodextrin-peptide conjugates for sequence specific DNA binding by Ruiz García, Yara, Zelenka, Jan, Pabon, Y Vladimir, Iyer, Abhishek, Buděšínský, Miloš, Kraus, Tomáš, Smith, C I Edvard, Madder, Annemieke

“…Synthetic models of bZIP transcription factors have been developed with the capability of specific DNA recognition. Our design is based on the CuAAC mediated…”
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Sequence-selective DNA recognition and enhanced cellular up-take by peptide-steroid conjugates by Ruiz García, Yara, Iyer, Abhishek, Van Lysebetten, Dorien, Pabon, Y Vladimir, Louage, Benoit, Honcharenko, Malgorzata, De Geest, Bruno G, Smith, C I Edvard, Strömberg, Roger, Madder, Annemieke

“…Several GCN4 bZIP TF models have previously been designed and synthesized. However, the synthetic routes towards these constructs are typically tedious and…”
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Range of invasive meningococcal disease sequelae and health economic application - a systematic and clinical review by Shen, Jing, Begum, Najida, Ruiz-Garcia, Yara, Martinon-Torres, Federico, Bekkat-Berkani, Rafik, Meszaros, Kinga

“…Invasive meningococcal disease (IMD) is uncommon, life-threatening, with many diverse sequelae. The aims were to: 1) comprehensively characterise the sequelae;…”
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A Decade of Fighting Invasive Meningococcal Disease: A Narrative Review of Clinical and Real-World Experience with the MenACWY-CRM Conjugate Vaccine by Ruiz Garcia, Yara, Abitbol, Véronique, Pellegrini, Michele, Bekkat-Berkani, Rafik, Soumahoro, Lamine

“…The quadrivalent A, C, W and Y meningococcal vaccine conjugated to nontoxic mutant of diphtheria toxin (MenACWY-CRM) has been licensed since 2010 for the…”
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Correction to: A Decade of Fighting Invasive Meningococcal Disease: A Narrative Review of Clinical and Real-World Experience with the MenACWY-CRM Conjugate Vaccine by Ruiz Garcia, Yara, Abitbol, Véronique, Pellegrini, Michele, Bekkat-Berkani, Rafik, Soumahoro, Lamine

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02. Beyond B Antigen Coverage: The Potential of the 4CMenB Vaccine for Cross-protection Against Pathogenic Neisseria Infections by Garcia, Yara Ruiz, Sohn, Woo-Yun, Pizza, Mariagrazia, Bekkat-Berkani, Rafik

“…Abstract Background Two human pathogenic Neisseria species exist: N. meningitidis (Nm) and N. gonorrhoeae (Ng). Although causing disparate clinical syndromes,…”
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An immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies by SANDERS, Melanie, GUO, Yirong, EREMIN, Sergei, MADDER, Annemieke, DE SAEGER, Sarah, IYER, Abhishek, GARCIA, Yara Ruiz, GALVITA, Anastasia, HEYERICK, Arne, DEFORCE, Dieter, RISSEEUW, Martijn D. P, VAN CALENBERGH, Serge, BRACKE, Marc

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