Search Results - "Ruiz‐Patiño, Alejandro"
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1
EGFR exon 20 insertion in lung adenocarcinomas among Hispanics (geno1.2-CLICaP)
Published in Lung cancer (Amsterdam, Netherlands) (01-11-2018)“…•Among 4005 lung adenocarcinoma patients we identified 88 EGFR exon 20 insertions.•Most patients with an exon 20 insertion were female and never-smokers.•36.4%…”
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2
Systemic management of malignant meningiomas: A comparative survival and molecular marker analysis between Octreotide in combination with Everolimus and Sunitinib
Published in PloS one (20-06-2019)“…To compare the effectiveness of octreotide/everolimus vs. sunitinib for the systemic treatment of recurrent aggressive meningiomas. 31 patients with recurrent…”
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3
Cost-utility analysis of genomic profiling in early breast cancer in Colombia
Published in Cost effectiveness and resource allocation (10-07-2023)“…In Colombia, the best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) remains unknown. This study aimed to identify the…”
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4
Bispecific Antibodies in Cancer Immunotherapy: A Novel Response to an Old Question
Published in Pharmaceutics (11-06-2022)“…Immunotherapy has redefined the treatment of cancer patients and it is constantly generating new advances and approaches. Among the multiple options of…”
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5
Application of Comprehensive Genomic Profiling-Based Next-Generation Sequencing Assay to Improve Cancer Care in a Developing Country
Published in Cancer control (01-01-2023)“…Purpose Identifying actionable oncogenic mutations have changed the therapeutic landscape in different types of tumors. This study investigated the utility of…”
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6
p.G12C KRAS mutation prevalence in non-small cell lung cancer: Contribution from interregional variability and population substructures among Hispanics
Published in Translational oncology (01-01-2022)“…•The identification of the KRAS G12C mutation in non-small cell lung cancer is relevant with new molecules being introduced for treatment.•The variation of…”
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7
Case Report: Differential Genomics and Evolution of a Meningeal Melanoma Treated With Ipilimumab and Nivolumab
Published in Frontiers in oncology (05-01-2022)“…Primary melanocytic tumors of the CNS are extremely rare conditions, encompassing different disease processes including meningeal melanoma and meningeal…”
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8
Multigene Mutation Profiling and Clinical Characteristics of Small-Cell Lung Cancer in Never-Smokers vs. Heavy Smokers (Geno1.3-CLICaP)
Published in Frontiers in oncology (17-04-2019)“…Lung cancer is a heterogeneous disease. Presentation and prognosis are known to vary according to several factors, such as genetic and demographic…”
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9
Antibiotics impair immune checkpoint inhibitor effectiveness in Hispanic patients with non‐small cell lung cancer (AB‐CLICaP)
Published in Thoracic cancer (01-09-2020)“…Background The intestinal microbiota is an important factor in modulating immune‐mediated tumor cell destruction. Alterations in the microbiome composition…”
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10
Real-World Treatment Patterns, Survival, and Prediction of CNS Progression in ALK-Positive Non-Small-Cell Lung Cancer Patients Treated with First-Line Crizotinib in Latin America Oncology Practices
Published in Oncology (01-04-2018)“…This study describes the real-world characteristics, treatment sequencing, and outcomes among Hispanic patients with locally advanced/metastatic ALK-positive…”
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11
Refractory Bullous Pemphigoid in a Patient with Metastatic Lung Adenocarcinoma Treated with Pembrolizumab
Published in Case reports in oncology (01-01-2021)“…We present the case of a 73-year-old male patient with a history of tobacco use who presented with a central nervous system mass that was confirmed to be a…”
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12
Genotyping Squamous Cell Lung Carcinoma in Colombia (Geno1.1-CLICaP)
Published in Frontiers in oncology (15-12-2020)“…Lung cancer is a public health problem, and squamous cell carcinoma (SCC) is the second most prevalent subtype of this neoplasm. Compared to other subtypes,…”
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13
Molecular Tumor Board Improves Outcomes for Hispanic Patients With Advanced Solid Tumors
Published in JCO global oncology (01-01-2024)“…Multidisciplinary molecular tumor boards (MTBs) decode complex genomic data into clinical recommendations. Although MTBs are well-established in the oncology…”
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14
Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab – Diagnostic and Therapeutic Challenge: A Case Report
Published in Case reports in oncology (01-01-2020)“…Due to the widespread use of immune checkpoint inhibitors and the growing research efforts in this area, immune-mediated toxicity is well recognized…”
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15
Precision medicine and its implementation in patients with NTRK fusion genes: perspective from developing countries
Published in Therapeutic Advances in Respiratory Disease (2020)“…Precision oncology is the field that places emphasis on the diagnosis and treatment of tumors that harbor specific genomic alterations susceptible to…”
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Mortality and Advanced Support Requirement for Patients With Cancer With COVID-19: A Mathematical Dynamic Model for Latin America
Published in JCO global oncology (01-05-2020)“…In the midst of a global pandemic, evidence suggests that similar to other severe respiratory viral infections, patients with cancer are at higher risk of…”
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17
Cost-effectiveness of laparoscopic versus open appendectomy in developing nations: a Colombian analysis
Published in The Journal of surgical research (01-04-2018)“…Colombia is a developing nation in need for efficient resource administration in fields such as health care, where innovation is constant. Since the…”
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Importancia pronóstica de las mutaciones del gen promotor de la transcriptasa inversa de la telomerasa en los meningiomas de alto grado
Published in Biomédica (01-12-2022)“…Introducción. En los meningiomas, ocurren con frecuencia mutaciones en la región promotora de la transcriptasa inversa de la telomerasa.Objetivo. Estimar la…”
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Atypical Skin Manifestations During Immune Checkpoint Blockage in Coronavirus Disease 2019-Infected Patients With Lung Cancer
Published in Journal of thoracic oncology (01-11-2020)“…A new coronavirus, named severe acute respiratory syndrome-coronavirus-2 by the WHO, has rapidly spread around the world since its first reported case in late…”
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STK11 and KEAP1 mutations in non-small cell lung cancer patients: Descriptive analysis and prognostic value among Hispanics (STRIKE registry-CLICaP)
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2022)“…•STK11 and KEAP1 have been described as poor prognostic factors in patients treated with immune checkpoint inhibitors (ICIs).•This is the larger study to…”
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