Search Results - "Ruiz‐Pérez, M V"

Pharmacological potential of biogenic amine–polyamine interactions beyond neurotransmission by Sánchez‐Jiménez, F, Ruiz‐Pérez, M V, Urdiales, J L, Medina, M A

“…Histamine, serotonin and dopamine are biogenic amines involved in intercellular communication with multiple effects on human pathophysiology. They are products…”
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A re-evaluation of the mitogenic effect of serotonin on vascular endothelial cells by Ruiz-Perez, M V, Sanchez-Jimenez, F, Quesada, A R, Medina, M A

“…Serotonin is an extracellular mediator recognized by seven different types of receptors, thus giving rise to pleiotropic intracellular responses. One of these…”
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Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma by Sainero-Alcolado, Lourdes, Garde-Lapido, Elisa, Snaebjörnsson, Marteinn Thor, Schoch, Sarah, Stevens, Irene, Ruiz-Pérez, María Victoria, Dyrager, Christine, Pelechano, Vicent, Axelson, Håkan, Schulze, Almut, Arsenian-Henriksson, Marie

“…Metabolic reprogramming is critical during clear cell renal cell carcinoma (ccRCC) tumorigenesis, manifested by accumulation of lipid droplets (LDs),…”
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Targeting mitochondrial metabolism for precision medicine in cancer by Sainero-Alcolado, Lourdes, Liaño-Pons, Judit, Ruiz-Pérez, María Victoria, Arsenian-Henriksson, Marie

“…During decades, the research field of cancer metabolism was based on the Warburg effect, described almost one century ago. Lately, the key role of mitochondria…”
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The MYCN Protein in Health and Disease by Ruiz-Pérez, María Victoria, Henley, Aine Brigette, Arsenian-Henriksson, Marie

“…is a member of the family of proto-oncogenes. It encodes a transcription factor, MYCN, involved in the control of fundamental processes during embryonal…”
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Metabolic restructuring and cell fate conversion by Prigione, Alessandro, Ruiz-Pérez, María Victoria, Bukowiecki, Raul, Adjaye, James

“…Accumulating evidence implicates mitochondrial and metabolic pathways in the establishment of pluripotency, as well as in the control of proliferation and…”
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Expression and activation of nuclear hormone receptors result in neuronal differentiation and favorable prognosis in neuroblastoma by Sainero-Alcolado, Lourdes, Mushtaq, Muhammad, Liaño-Pons, Judit, Rodriguez-Garcia, Aida, Yuan, Ye, Liu, Tong, Ruiz-Pérez, María Victoria, Schlisio, Susanne, Bedoya-Reina, Oscar, Arsenian-Henriksson, Marie

“…Neuroblastoma (NB), a childhood tumor derived from the sympathetic nervous system, presents with heterogeneous clinical behavior. While some tumors regress…”
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Polyamine Metabolism Is Sensitive to Glycolysis Inhibition in Human Neuroblastoma Cells by Ruiz-Pérez, M. Victoria, Medina, Miguel Ángel, Urdiales, José Luis, Keinänen, Tuomo A., Sánchez-Jiménez, Francisca

“…Polyamines are essential for cell proliferation, and their levels are elevated in many human tumors. The oncogene n-myc is known to potentiate polyamine…”
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MYCN-enhanced Oxidative and Glycolytic Metabolism Reveals Vulnerabilities for Targeting Neuroblastoma by Oliynyk, Ganna, Ruiz-Pérez, María Victoria, Sainero-Alcolado, Lourdes, Dzieran, Johanna, Zirath, Hanna, Gallart-Ayala, Héctor, Wheelock, Craig E., Johansson, Henrik J., Nilsson, Roland, Lehtiö, Janne, Arsenian-Henriksson, Marie

“…In pediatric neuroblastoma, MYCN-amplification correlates to poor clinical outcome and new treatment options are needed for these patients. Identifying the…”
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Glutamine, glucose and other fuels for cancer by Ruiz-Perez, Maria Victoria, Sanchez-Jimenez, Francisca, Alonso, Francisco J, Segura, Juan A, Marquez, Javier, Medina, Miguel Angel

“…Tumor cells suffer a metabolic reprogramming which allows them to use metabolic fuels (glucose, glutamine, lipids) through anabolic fates to support their…”
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Inhibition of fatty acid synthesis induces differentiation and reduces tumor burden in childhood neuroblastoma by Ruiz-Pérez, María Victoria, Sainero-Alcolado, Lourdes, Oliynyk, Ganna, Matuschek, Isabell, Balboni, Nicola, Ubhayasekera, S.J. Kumari A., Snaebjornsson, Marteinn Thor, Makowski, Kamil, Aaltonen, Kristina, Bexell, Daniel, Serra, Dolors, Nilsson, Roland, Bergquist, Jonas, Schulze, Almut, Arsenian-Henriksson, Marie

“…Many metabolic pathways, including lipid metabolism, are rewired in tumors to support energy and biomass production and to allow adaptation to stressful…”
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Nascent histamine induces α-synuclein and caspase-3 on human cells by Caro-Astorga, Joaquín, Fajardo, Ignacio, Ruiz-Pérez, María Victoria, Sánchez-Jiménez, Francisca, Urdiales, José Luis

“…•Nascent histamine alters cyclin expression pattern.•Nascent histamine increases expression of α-synuclein.•Nascent histamine activates caspase-3. Histamine…”
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Structural Perspective on the Direct Inhibition Mechanism of EGCG on Mammalian Histidine Decarboxylase and DOPA Decarboxylase by Ruiz-Pérez, M. Victoria, Pino-Ángeles, Almudena, Medina, Miguel A, Sánchez-Jiménez, Francisca, Moya-García, Aurelio A

“…Histidine decarboxylase (HDC) and l-aromatic amino acid decarboxylase (DDC) are homologous enzymes that are responsible for the synthesis of important…”
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