Search Results - "Ruiz‐Gaspà, Silvia"

Sclerostin Expression in Bile Ducts of Patients With Chronic Cholestasis May Influence the Bone Disease in Primary Biliary Cirrhosis by Guañabens, Núria, Ruiz‐Gaspà, Silvia, Gifre, Laia, Miquel, Rosa, Peris, Pilar, Monegal, Ana, Dubrueil, Marta, Arias, Ana, Parés, Albert

“…ABSTRACT Sclerostin is involved in the regulation of osteoblastogenesis and little is known about its role in the development of bone disease in primary…”
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Effect of Recent Spinal Cord Injury on Wnt Signaling Antagonists (Sclerostin and Dkk‐1) and Their Relationship With Bone Loss. A 12‐Month Prospective Study by Gifre, Laia, Vidal, Joan, Carrasco, Josep L, Filella, Xavier, Ruiz‐Gaspà, Silvia, Muxi, Africa, Portell, Enric, Monegal, Ana, Guañabens, Nuria, Peris, Pilar

“…Spinal cord injury (SCI) has been associated with a marked increase in bone loss and bone remodeling, especially short‐term after injury. The absence of…”
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Effects of bilirubin and sera from jaundiced patients on osteoblasts: Contribution to the development of osteoporosis in liver diseases by Ruiz‐Gaspà, Silvia, Martinez‐Ferrer, Angels, Guañabens, Nuria, Dubreuil, Marta, Peris, Pilar, Enjuanes, Anna, Martinez de Osaba, Maria Jesús, Alvarez, Luisa, Monegal, Ana, Combalia, Andrés, Parés, Albert

“…Low bone formation is considered to be the main feature in osteoporosis associated with cholestatic and end‐stage liver diseases, although the consequences of…”
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Idiopathic Acquired Osteosclerosis in a Middle‐Aged Woman With Systemic Lupus Erythematosus by Guañabens, Núria, Mumm, Steven, Gifre, Laia, Ruiz‐Gaspà, Silvia, Demertzis, Jennifer L, Stolina, Marina, Novack, Deborah V, Whyte, Michael P

“…ABSTRACT Widely distributed osteosclerosis is an unusual radiographic finding with multiple causes. A 42‐year‐old premenopausal Spanish woman gradually…”
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The genomic landscape of transformed splenic diffuse red pulp small B‐cell lymphoma by Grau, Marta, Pol, Melina, Montaner, Anna, Mozas, Pablo, Nadeu, Ferran, Márquez‐López, Ian, Álamo, Jose Ramon, Navarro, Alba, Martinez, Daniel, Frigola, Gerard, Balagué, Olga, Lopez‐Guerra, Mónica, Colomer, Dolors, Ruiz‐Gaspà, Silvia, Bashiri, Melika, Correa, Juan, Giné, Eva, López‐Guillermo, Armando, Campo, Elias, López, Cristina, Matutes, Estella, Beà, Sílvia

“…The genetic landscape underlying the transformation of splenic diffuse red pulp small B‐cell lymphoma (SDRPL) is not well understood. The present study aimed…”
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Ursodeoxycholic acid increases differentiation and mineralization and neutralizes the damaging effects of bilirubin on osteoblastic cells by Dubreuil, Marta, Ruiz-Gaspà, Silvia, Guañabens, Nuria, Peris, Pilar, Álvarez, Luisa, Monegal, Ana, Combalia, Andrés, Parés, Albert

“…Background Osteoporosis resulting from decreased bone formation is a common complication in patients with chronic cholestasis. Lithocholic acid (LCA) and…”
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Vertebral fracture risk in glucocorticoid-induced osteoporosis: the role of hypogonadism and corticosteroid boluses by Florez, Helena, Hernández-Rodríguez, Jose, Carrasco, Josep Lluis, Prieto-González, Sergio, Muxi, Africa, Filella, Xavier, Ruiz-Gaspà, Silvia, Gómez-Puerta, José A, Cid, Maria, Espinosa, Gerard, Monegal, Ana, Guañabens, Núria, Peris, Pilar

“…ObjectiveThe aim of this study was to identify the risk factors associated with fragility fracture (FF) development in glucocorticoid (GC)-treated…”
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Bilirubin and bile acids in osteocytes and bone tissue. Potential role in the cholestatic‐induced osteoporosis by Ruiz‐Gaspà, Silvia, Guañabens, Núria, Jurado, Susana, Combalia, Andreu, Peris, Pilar, Monegal, Ana, Parés, Albert

“…Background and Aims Osteoporosis is a common complication in patients with primary biliary cholangitis. Both bilirubin and lithocholic acid (LCA) result in…”
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Novel Anti–Hexokinase 1 Antibodies Are Associated With Poor Prognosis in Patients With Primary Biliary Cholangitis by Reig, Anna, Norman, Gary L., Garcia, Mila, Shums, Zakera, Ruiz-Gaspà, Silvia, Bentow, Chelsea, Mahler, Michael, Romera, Maria A., Vinas, Odette, Pares, Albert

“…Antibodies to hexokinase 1 (HK1) and kelch-like 12 (KLHL12) have been identified as potential biomarkers in primary biliary cholangitis (PBC), and this study…”
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Bile acids and bilirubin effects on osteoblastic gene profile. Implications in the pathogenesis of osteoporosis in liver diseases by Ruiz-Gaspà, Silvia, Guañabens, Nuria, Jurado, Susana, Dubreuil, Marta, Combalia, Andres, Peris, Pilar, Monegal, Ana, Parés, Albert

“…Osteoporosis in advanced cholestatic and end-stage liver disease is related to low bone formation. Previous studies have demonstrated the deleterious…”
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Functional analysis of the I.3, I.6, pII and I.4 promoters of CYP19 (aromatase) gene in human osteoblasts and their role in vitamin D and dexamethasone stimulation by Enjuanes, Anna, Garcia-Giralt, Natalia, Supervía, August, Nogués, Xavier, Ruiz-Gaspà, Silvia, Bustamante, Mariona, Mellibovsky, Leonardo, Grinberg, Daniel, Balcells, Susana, Díez-Pérez, Adolfo

“…Objective: Current evidence suggests that extragonadal estrogens play an important role in bone metabolism. Estrogen biosynthesis is catalyzed by…”
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p38 Regulates Expression of Osteoblast-specific Genes by Phosphorylation of Osterix by Ortuño, María José, Ruiz-Gaspà, Silvia, Rodríguez-Carballo, Edgardo, Susperregui, Antonio R.G., Bartrons, Ramon, Rosa, José Luis, Ventura, Francesc

“…Osterix, a zinc finger transcription factor, is specifically expressed in osteoblasts and osteocytes of all developing bones. Because no bone formation occurs…”
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Ursodeoxycholic acid decreases bilirubin-induced osteoblast apoptosis by Ruiz-Gaspà, Silvia, Dubreuil, Marta, Guañabens, Nuria, Combalia, Andrés, Peris, Pilar, Monegal, Ana, Parés, Albert

“…Background Low bone turnover osteoporosis is common in cholestatic diseases. Ursodeoxycholic acid (UDCA) counteracts the damaging effects of bilirubin or…”
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Large B-cell lymphomas with CCND1 rearrangement have different immunoglobulin gene breakpoints and genomic profile than mantle cell lymphoma by Özoğul, Ece, Montaner, Anna, Pol, Melina, Frigola, Gerard, Balagué, Olga, Syrykh, Charlotte, Bousquets-Muñoz, Pablo, Royo, Romina, Fontaine, Juliette, Traverse-Glehen, Alexandra, Bühler, Marco M., Giudici, Luca, Roncador, Marco, Zenz, Thorsten, Carras, Sylvain, Valmary-Degano, Severine, de Leval, Laurence, Bosch-Schips, Jan, Climent, Fina, Salmeron-Villalobos, Julia, Bashiri, Melika, Ruiz-Gaspà, Silvia, Costa, Dolors, Beà, Sílvia, Salaverria, Itziar, Giné, Eva, Quintanilla-Martinez, Leticia, Brousset, Pierre, Raffeld, Mark, Jaffe, Elaine S., Puente, Xose S., López, Cristina, Nadeu, Ferran, Campo, Elias

“…Mantle cell lymphoma (MCL) is genetically characterized by the IG :: CCND1 translocation mediated by an aberrant V(D)J rearrangement. CCND1 translocations and…”
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All‐CLL: A Capture‐based Next‐generation Sequencing Panel for the Molecular Characterization of Chronic Lymphocytic Leukemia by López‐Oreja, Irene, López‐Guerra, Mónica, Correa, Juan, Mozas, Pablo, Muntañola, Ana, Muñoz, Luz, Salgado, Ana‐Camino, Ruiz‐Gaspà, Sílvia, Costa, Dolors, Beà, Sílvia, Jares, Pedro, Campo, Elías, Colomer, Dolors, Nadeu, Ferran

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Simvastatin and atorvastatin enhance gene expression of collagen type 1 and osteocalcin in primary human osteoblasts and MG-63 cultures by Ruiz-Gaspa, Silvia, Nogues, Xavier, Enjuanes, Anna, Monllau, Joan C., Blanch, Josep, Carreras, Ramon, Mellibovsky, Leonardo, Grinberg, Daniel, Balcells, Susana, Díez-Perez, Adolfo, Pedro-Botet, Juan

“…To clarify the mechanism of the stimulatory effect of statins on bone formation, we have assessed the effect of simvastatin and atorvastatin on osteoblast…”
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Detection of early seeding of Richter transformation in chronic lymphocytic leukemia by Nadeu, Ferran, Royo, Romina, Massoni-Badosa, Ramon, Playa-Albinyana, Heribert, Garcia-Torre, Beatriz, Duran-Ferrer, Martí, Dawson, Kevin J., Kulis, Marta, Diaz-Navarro, Ander, Villamor, Neus, Melero, Juan L., Chapaprieta, Vicente, Dueso-Barroso, Ana, Delgado, Julio, Moia, Riccardo, Ruiz-Gil, Sara, Marchese, Domenica, Giró, Ariadna, Verdaguer-Dot, Núria, Romo, Mónica, Clot, Guillem, Rozman, Maria, Frigola, Gerard, Rivas-Delgado, Alfredo, Baumann, Tycho, Alcoceba, Miguel, González, Marcos, Climent, Fina, Abrisqueta, Pau, Castellví, Josep, Bosch, Francesc, Aymerich, Marta, Enjuanes, Anna, Ruiz-Gaspà, Sílvia, López-Guillermo, Armando, Jares, Pedro, Beà, Sílvia, Capella-Gutierrez, Salvador, Gelpí, Josep Ll, López-Bigas, Núria, Torrents, David, Campbell, Peter J., Gut, Ivo, Rossi, Davide, Gaidano, Gianluca, Puente, Xose S., Garcia-Roves, Pablo M., Colomer, Dolors, Heyn, Holger, Maura, Francesco, Martín-Subero, José I., Campo, Elías

“…Richter transformation (RT) is a paradigmatic evolution of chronic lymphocytic leukemia (CLL) into a very aggressive large B cell lymphoma conferring a dismal…”
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The effect of the alendronate on OPG/RANKL system in differentiated primary human osteoblasts by Enjuanes, Anna, Ruiz-Gaspà, Silvia, Peris, Pilar, Ozalla, Dolores, Álvarez, Luisa, Combalia, Andrés, Martínez de Osaba, M. Jesús, Monegal, Ana, Pares, Albert, Guañabens, Nuria

“…Alendronate is a well-established treatment for osteoporosis and suppresses bone resorption by a direct effect on osteoclasts and their precursors. The effect…”
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The effect of the alendronate on OPG/RANKL system in differentiated primary human osteoblasts by Enjuanes, Anna, Ruiz-Gaspà, Silvia, Peris, Pilar, Ozalla, Dolores, Álvarez, Luisa, Combalia, Andrés, Martínez de Osaba, M. Jesús, Monegal, Ana, Pares, Albert, Guañabens, Nuria

“…Alendronate is a well-established treatment for osteoporosis and suppresses bone resorption by a direct effect on osteoclasts and their precursors. The effect…”
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A new SNP in a negative regulatory region of the CYP19A1 gene is associated with lumbar spine BMD in postmenopausal women by Enjuanes, Anna, Garcia-Giralt, Natalia, Supervía, August, Nogués, Xavier, Ruiz-Gaspà, Silvia, Bustamante, Mariona, Mellibovsky, Leonardo, Grinberg, Daniel, Balcells, Susana, Díez-Pérez, Adolfo

“…Osteoporosis is a common disease of bone possessing a strong genetic component. Cytochrome P450 aromatase, which is encoded by the CYP19A1 gene, converts…”
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