Search Results - "Ruiz‐Bañobre, Juan"

Noninvasive detection of microsatellite instability in patients with endometrial cancer by Casas‐Arozamena, Carlos, Moiola, Cristian Pablo, Vilar, Ana, Bouso, Marta, Cueva, Juan, Cabrera, Silvia, Sampayo, Victoria, Arias, Efigenia, Abalo, Alicia, García, Ángel, Lago‐Lestón, Ramón Manuel, Oltra, Sara, Díaz, Eva, Ruiz‐Bañobre, Juan, López‐López, Rafael, Moreno‐Bueno, Gema, Gil‐Moreno, Antonio, Colás, Eva, Abal, Miguel, Muinelo‐Romay, Laura

“…The analysis of mismatch repair proteins in solid tissue is the standard of care (SoC) for the microsatellite instability (MSI) characterization in endometrial…”
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Genetic and immune landscape evolution in MMR-deficient colorectal cancer by Challoner, Benjamin R, Woolston, Andrew, Lau, David, Buzzetti, Marta, Fong, Caroline, Barber, Louise J, Anandappa, Gayathri, Crux, Richard, Assiotis, Ioannis, Fenwick, Kerry, Begum, Ruwaida, Begum, Dipa, Lund, Tom, Sivamanoharan, Nanna, Sansano, Harold B, Domingo-Arada, Melissa, Tran, Amina, Pandha, Hardev, Church, David, Eccles, Bryony, Ellis, Richard, Falk, Stephen, Hill, Mark, Krell, Daniel, Murugaesu, Nirupa, Nolan, Luke, Potter, Vanessa, Saunders, Mark, Shiu, Kai-Keen, Guettler, Sebastian, Alexander, James L, Lázare-Iglesias, Héctor, Kinross, James, Murphy, Jamie, von Loga, Katharina, Cunningham, David, Chau, Ian, Starling, Naureen, Ruiz-Bañobre, Juan, Dhillon, Tony, Gerlinger, Marco

“…Mismatch repair-deficient (MMRd) colorectal cancers (CRCs) have high mutation burdens, which make these tumours immunogenic and many respond to immune…”
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Severe de novo pustular psoriasiform immune‐related adverse event associated with nivolumab treatment for metastatic esophageal adenocarcinoma by Seervai, Riyad N. H., Heberton, Meghan, Cho, Woo Cheal, Gill, Pavandeep, Murphy, Mariela B., Aung, Phyu P., Nagarajan, Priyadharsini, Torres‐Cabala, Carlos A., Patel, Anisha B., Ruiz‐Bañobre, Juan, Om, Amit, Yamamoto, Toshiyuki, Nikolaou, Vasiliki, Curry, Jonathan L.

“…Breakthrough targeted therapies have produced significant improvements in survival for cancer patients, but have a propensity to cause cutaneous immune‐related…”
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Ascites-Derived Organoids to Depict Platinum Resistance in Gynaecological Serous Carcinomas by Arias-Diaz, Andrea Estrella, Ferreiro-Pantin, Miriam, Barbazan, Jorge, Perez-Beliz, Edurne, Ruiz-Bañobre, Juan, Casas-Arozamena, Carlos, Muinelo-Romay, Laura, Lopez-Lopez, Rafael, Vilar, Ana, Curiel, Teresa, Abal, Miguel

“…Gynaecological serous carcinomas (GSCs) constitute a distinctive entity among female tumours characterised by a very poor prognosis. In addition to late-stage…”
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Clinical significance of baseline Pan-Immune-Inflammation Value and its dynamics in metastatic colorectal cancer patients under first-line chemotherapy by Pérez-Martelo, Martín, González-García, Alejandro, Vidal-Ínsua, Yolanda, Blanco-Freire, Cristina, Brozos-Vázquez, Elena María, Abdulkader-Nallib, Ihab, Álvarez-Fernández, Javier, Lázare-Iglesias, Héctor, García-Martínez, Carolina, Betancor, Yoel Z., Sánchez-Ares, María, Tubío, Jose M. C., Vázquez-Rivera, Francisca, Candamio-Folgar, Sonia, López-López, Rafael, Ruiz-Bañobre, Juan

“…Pan-Immune-Inflammation Value (PIV) has been recently proposed as a new blood-based prognostic biomarker in metastatic colorectal cancer (mCRC). Herein we…”
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Development of de novo psoriasis during nivolumab therapy for metastatic renal cell carcinoma: immunohistochemical analyses and clinical outcome by Ruiz‐Bañobre, Juan, Abdulkader, Ihab, Anido, Urbano, León, Luis, López‐López, Rafael, García‐González, Jorge

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Role of cfDNA and ctDNA to improve the risk stratification and the disease follow-up in patients with endometrial cancer: towards the clinical application by Casas-Arozamena, Carlos, Vilar, Ana, Cueva, Juan, Arias, Efigenia, Sampayo, Victoria, Diaz, Eva, Oltra, Sara S, Moiola, Cristian Pablo, Cabrera, Silvia, Cortegoso, Alexandra, Curiel, Teresa, Abalo, Alicia, Pamies Serrano, Mónica, Domingo, Santiago, Padilla-Iserte, Pablo, Arnaez de la Cruz, Marta, Hernández, Alicia, García-Pineda, Virginia, Ruiz-Bañobre, Juan, López, Rafael, Matias-Guiu, Xavier, Colás, Eva, Gil-Moreno, Antonio, Abal, Miguel, Moreno-Bueno, Gema, Muinelo-Romay, Laura

“…There has been a rise in endometrial cancer (EC) incidence leading to increased mortality. To counter this trend, improving the stratification of post-surgery…”
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A three-gene expression score for predicting clinical benefit to anti-PD-1 blockade in advanced renal cell carcinoma by Betancor, Yoel Z, Ferreiro-Pantín, Miriam, Anido-Herranz, Urbano, Fuentes-Losada, Mar, León-Mateos, Luis, García-Acuña, Silvia Margarita, Vaamonde-Rodríguez, Vanessa, García-Pinel, Beatriz, Cebey-López, Víctor, Villaverde-Viaño, Rosa, Lombardía-Rodríguez, Helena, Kotrulev, Martin, Fernández-Díaz, Natalia, Gomez-Tourino, Iria, Fernández-Baltar, Carlos, García-González, Jorge, Tubio, Jose M C, López-López, Rafael, Ruiz-Bañobre, Juan

“…In the advanced renal cell carcinoma (RCC) scenario, there are no consistent biomarkers to predict the clinical benefit patients derived from immune checkpoint…”
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Outcomes and patterns of use of Radium-223 in metastatic castration-resistant prostate cancer by Anido-Herranz, Urbano, Fernandez-Calvo, Ovidio, Ruiz-Bañobre, Juan, Martinez-Breijo, Sara, Fernandez-Nuñez, Natalia, Nogareda-Seoane, Zulema, Garrido-Pumar, Miguel, Casas-Nebra, Javier, Muñiz-Garcia, Gloria, Portela-Pereira, Paula, Gomez-Caamaño, Antonio, Perez-Fentes, Daniel Adolfo, Santome-Couto, Lucia, Lázaro, Martín, Molina-Diaz, Aurea, Medina-Colmenero, Ana, Vazquez-Estevez, Sergio

“…Radium-223 dichloride (Ra-223) is recommended as a treatment option for metastatic castration-resistant prostate cancer (mCRPC) patients with symptomatic bone…”
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Long-term Response to Nivolumab and Acute Renal Failure in a Patient with Metastatic Papillary Renal Cell Carcinoma and a PD-L1 Tumor Expression Increased with Sunitinib Therapy: A Case Report by Ruiz-Bañobre, Juan, Anido, Urbano, Abdulkader, Ihab, Antúnez-López, José, López-López, Rafael, García-González, Jorge

“…Papillary renal cell carcinoma (PRCC), which represents around 20% of renal cell carcinomas, is a heterogeneous disease that includes different tumor types…”
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MSIMEP: Predicting microsatellite instability from microarray DNA methylation tumor profiles by Santamarina-García, Martín, Brea-Iglesias, Jenifer, Bramsen, Jesper Bertram, Fuentes-Losada, Mar, Caneiro-Gómez, Francisco Javier, Vázquez-Bueno, José Ángel, Lázare-Iglesias, Héctor, Fernández-Díaz, Natalia, Sánchez-Rivadulla, Laura, Betancor, Yoel Z., Ferreiro-Pantín, Miriam, Conesa-Zamora, Pablo, Antúnez-López, José Ramón, Kawazu, Masahito, Esteller, Manel, Andersen, Claus Lindbjerg, Tubio, Jose M.C., López-López, Rafael, Ruiz-Bañobre, Juan

“…Deficiency in DNA MMR activity results in tumors with a hypermutator phenotype, termed microsatellite instability (MSI). Beyond its utility in Lynch syndrome…”
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DNA Mismatch Repair Deficiency and Immune Checkpoint Inhibitors in Gastrointestinal Cancers by Ruiz-Bañobre, Juan, Goel, Ajay

“…In the recent few years, significant efforts have been undertaken for the development of different immunotherapeutic approaches against cancer. In this…”
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Clinical significance of a microRNA signature for the identification and predicting prognosis in colorectal cancers with mucinous differentiation by Ruiz-Bañobre, Juan, Roy, Roshni, Alustiza Fernández, Miren, Murcia, Óscar, Jover, Rodrigo, Pera, Miguel, Balaguer, Francesc, López-López, Rafael, Goel, Ajay

“…Abstract Accumulating evidence supports the fact that the mere presence of mucinous differentiation in colorectal cancer (CRC), rather than its proportion, is…”
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Versatile protamine nanocapsules to restore miR-145 levels and interfere tumor growth in colorectal cancer cells by Reimondez-Troitiño, Sonia, González-Aramundiz, José V., Ruiz-Bañobre, Juan, López-López, Rafael, Alonso, María J., Csaba, Noemi, de la Fuente, María

“…[Display omitted] MicroRNAs (miRNAs) play a key role on gene expression regulation contributing to cell homeostasis, and they are highly dysregulated in…”
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Development of psoriatic arthritis during nivolumab therapy for metastatic non-small cell lung cancer, clinical outcome analysis and review of the literature by Ruiz-Bañobre, Juan, Pérez-Pampín, Eva, García-González, Jorge, Gómez-Caamaño, Antonio, Barón-Duarte, Francisco Javier, López-López, Rafael, Vázquez-Rivera, Francisca

“…Highlights • It is the second case of psoriatic arthritis development during nivolumab therapy. • Low psoriatic arthritis activity was achieved without…”
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Noninvasive early detection of colorectal cancer by hypermethylation of the LINC00473 promoter in plasma cell-free DNA by Ruiz-Bañobre, Juan, Rodriguez-Casanova, Aitor, Costa-Fraga, Nicolas, Bao-Caamano, Aida, Alvarez-Castro, Ana, Carreras-Presas, Martín, Brozos-Vazquez, Elena, Vidal-Insua, Yolanda, Vazquez-Rivera, Francisca, Candamio-Folgar, Sonia, Mosquera-Presedo, Manuel, Lago-Lestón, Ramón M, Muinelo-Romay, Laura, Vázquez-Bueno, José Ángel, Sanz-Pamplona, Rebeca, Moreno, Víctor, Goel, Ajay, Castillo, Lourdes, Martin, Ana C, Arroyo, Rocio, Esteller, Manel, Crujeiras, Ana B, López-López, Rafael, Díaz-Lagares, Angel

“…Current noninvasive assays have limitations in the early detection of colorectal cancer. We evaluated the clinical utility of promoter methylation of the long…”
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Evaluation of the lung immune prognostic index in advanced non-small cell lung cancer patients under nivolumab monotherapy by Ruiz-Bañobre, Juan, Areses-Manrique, María C., Mosquera-Martínez, Joaquín, Cortegoso, Alexandra, Afonso-Afonso, Francisco J., de Dios-Álvarez, Noemí, Fernández-Núñez, Natalia, Azpitarte-Raposeiras, Cristina, Amenedo, Margarita, Santomé, Lucía, Fírvida-Pérez, José Luis, García-Campelo, Rosario, García-González, Jorge, Casal-Rubio, Joaquín, Vázquez, Sergio

“…The lung immune prognostic index (LIPI) has been proposed as a new categorical blood-based biomarker to select advanced non-small cell lung cancer (NSCLC)…”
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PD-(L)1 Inhibitors in Combination with Chemotherapy as First-Line Treatment for Non-Small-Cell Lung Cancer: A Pairwise Meta-Analysis by García-González, Jorge, Ruiz-Bañobre, Juan, Afonso-Afonso, Francisco J, Amenedo-Gancedo, Margarita, Areses-Manrique, María Del Carmen, Campos-Balea, Begoña, Casal-Rubio, Joaquín, Fernández-Núñez, Natalia, Fírvida Pérez, José Luis, Lázaro-Quintela, Martín, Pérez Parente, Diego, Crama, Leonardo, Ruiz-Gracia, Pedro, Santomé-Couto, Lucía, León-Mateos, Luis

“…The combination of programmed cell death-1 (PD-1)/programmed death ligand-1 (PD-L1) inhibitors with chemotherapy has emerged as a promising therapeutic option…”
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Efficacy and safety of Nivolumab in older patients with pretreated lung cancer: A subgroup analysis of the Galician lung cancer group by Arias Ron, David, Areses Manrique, Maria Carmen, Mosquera Martínez, Joaquín, García González, Jorge, Afonso Afonso, Francisco Javier, Lázaro Quintela, Martín, Fernández Núñez, Natalia, Azpitarte Raposeiras, Cristina, Amenedo Gancedo, Margarita, Santomé Couto, Lucía, García Campelo, María Rosario, Muñoz Iglesias, Jose, Ruiz Bañobre, Juan, Vilchez Simo, Rocío, Casal Rubio, Joaquín, Campos Balea, Begoña, Carou Frieiro, Iria, Alonso-Jaudenes Curbera, Guillermo, Anido Herranz, Urbano, García Mata, Jesús, Fírvida Pérez, Jose Luis

“…Nivolumab is an anti PD1 immunotherapy drug approved for advanced Non-Small Cell Lung Cancer (NSCLC) patients who previously received at least one prior line…”
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Genomic and epigenomic biomarkers in colorectal cancer: From diagnosis to therapy by Ruiz-Bañobre, Juan, Goel, Ajay

“…Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. Despite ongoing efforts aimed at increasing screening for…”
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