Search Results - "Ruiz, Reinaldo Molina"

A topological substructural approach applied to the computational prediction of rodent carcinogenicity by Helguera, Aliuska Morales, Cabrera Pérez, Miguel Angel, González, Maykel Pérez, Ruiz, Reinaldo Molina, González Díaz, Humberto

“…The rodent carcinogenic activity was investigated by using a topological substructural molecular design approach (TOPS-MODE). The in silico model obtained…”
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2-(2-Methyl-2-nitrovinyl)furan but Not Furvina Interfere with Staphylococcus aureus Agr Quorum-Sensing System and Potentiate the Action of Fusidic Acid against Biofilms by Oliveira, Diana, Borges, Anabela, Ruiz, Reinaldo Molina, Negrín, Zenaida Rodríguez, Distinto, Simona, Borges, Fernanda, Simões, Manuel

“…Quorum sensing (QS) plays an essential role in the production of virulence factors, in biofilm formation and antimicrobial resistance. Consequently, inhibiting…”
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Surveying alignment-free features for Ortholog detection in related yeast proteomes by using supervised big data classifiers by Galpert, Deborah, Fernández, Alberto, Herrera, Francisco, Antunes, Agostinho, Molina-Ruiz, Reinaldo, Agüero-Chapin, Guillermin

“…The development of new ortholog detection algorithms and the improvement of existing ones are of major importance in functional genomics. We have previously…”
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Graph Theory-Based Sequence Descriptors as Remote Homology Predictors by Agüero-Chapin, Guillermin, Galpert, Deborah, Molina-Ruiz, Reinaldo, Ancede-Gallardo, Evys, Pérez-Machado, Gisselle, de la Riva, Gustavo A, Antunes, Agostinho

“…Alignment-free (AF) methodologies have increased in popularity in the last decades as alternative tools to alignment-based (AB) algorithms for performing…”
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Development and validation of a gas chromatography with a flame ionization detector method for quantitative analysis of four major fatty acids extracted shark liver oil by Pedro C. Quero-Jiménez, Lester A. Arias Felipe, María E. Jorge Rodríguez, Reinaldo Molina Ruiz, Julio O. Prieto García, Jorge B. de la Torre López, Osvaldo N. Montenegro

“…Context: The shark liver of the species Ginglimostoma cirratun, Carcharhinus longimanus, and Carcharhinus falciformis, captured in the north-central coast of…”
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Local Cuban bentonite clay as potential low-cost adsorbent for shark liver oil pool purification by Quero-Jiménez, Pedro C., Arias Felipe, Lester A., Prieto García, Julio O., Jorge Rodríguez, María E., de la Torre López, Jorge B., Montenegro, Osvaldo N., Molina Ruiz, Reinaldo

“…Context: The shark liver of the species Ginglimostoma cirratun, Carcharhinus longimanus, and Carcharhinus falciformis, captured in the north-central coast of…”
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Exploring the adenylation domain repertoire of nonribosomal peptide synthetases using an ensemble of sequence-search methods by Agüero-Chapin, Guillermin, Molina-Ruiz, Reinaldo, Maldonado, Emanuel, de la Riva, Gustavo, Sánchez-Rodríguez, Aminael, Vasconcelos, Vitor, Antunes, Agostinho

“…The introduction of two-dimension (2D) graphs and their numerical characterization for comparative analyses of DNA/RNA and protein sequences without the need…”
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An alignment-free approach for eukaryotic ITS2 annotation and phylogenetic inference by Agüero-Chapin, Guillermin, Sánchez-Rodríguez, Aminael, Hidalgo-Yanes, Pedro I, Pérez-Castillo, Yunierkis, Molina-Ruiz, Reinaldo, Marchal, Kathleen, Vasconcelos, Vítor, Antunes, Agostinho

“…The ITS2 gene class shows a high sequence divergence among its members that have complicated its annotation and its use for reconstructing phylogenies at a…”
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A novel approach to predict a toxicological property of aromatic compounds in the Tetrahymena pyriformis by González, Maykel Pérez, Dı́az, Humberto González, Cabrera, Miguel Angel, Ruiz, Reinaldo Molina

“…The TOPological Substructural MOlecular DEsign (TOPS-MODE) has been successfully used in order to explain the toxicity in the Tetrahymena pyriformis on a large…”
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TOPS-MODE Based QSARs Derived from Heterogeneous Series of Compounds. Applications to the Design of New Herbicides by González, Maykel Pérez, Díaz, Humberto Gonzalez, Ruiz, Reinaldo Molina, Cabrera, Miguel A, Ramos de Armas, Ronal

“…A new application of TOPological Sub-structural MOlecular DEsign (TOPS-MODE) was carried out in herbicides using computer-aided molecular design. Two series of…”
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Local Cuban bentonite clay: composition, structure and textural characterization by Quero-Jiménez, Pedro César, Arias Felipe, Lester Alejandro, Prieto García, Julio Omar, Jorge Rodríguez, María Elisa, De la Torre López, Jorge Basilio, Montenegro, Osvaldo Norman, Molina Ruíz, Reinaldo, Tiscornia, Inés Silvia

“…The physic and chemical characterization of the bentonite clay from the Chiqui Gómez deposit, central Cuba, (Cuban bentonite clay) shows that it is mainly…”
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A Novel Automated Framework for QSAR Modeling of Highly Imbalanced Leishmania High-Throughput Screening Data by Casanova-Alvarez, Omar, Morales-Helguera, Aliuska, Cabrera-Pérez, Miguel Ángel, Molina-Ruiz, Reinaldo, Molina, Christophe

“…In silico prediction of antileishmanial activity using quantitative structure–activity relationship (QSAR) models has been developed on limited and small…”
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The Harderian gland transcriptomes of Caraiba andreae, Cubophis cantherigerus and Tretanorhinus variabilis, three colubroid snakes from Cuba by Domínguez-Pérez, Dany, Durban, Jordi, Agüero-Chapin, Guillermin, López, Javier Torres, Molina-Ruiz, Reinaldo, Almeida, Daniela, Calvete, Juan J., Vasconcelos, Vítor, Antunes, Agostinho

“…The Harderian gland is a cephalic structure, widely distributed among vertebrates. In snakes, the Harderian gland is anatomically connected to the vomeronasal…”
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Development and validation of a gas chromatography with a flame ionization detector method for quantitative analysis of four major fatty acids extracted shark liver oil by Quero-Jiménez, Pedro C., Arias Felipe, Lester A., Jorge Rodríguez, María E., Molina Ruiz, Reinaldo, Prieto García, Julio O., de la Torre López, Jorge B., Montenegro, Osvaldo N.

“…Context: The shark liver of the species Ginglimostoma cirratun, Carcharhinus longimanus, and Carcharhinus falciformis, captured in the north-central coast of…”
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Desirability-Based Methods of Multiobjective Optimization and Ranking for Global QSAR Studies. Filtering Safe and Potent Drug Candidates from Combinatorial Libraries by Cruz-Monteagudo, Maykel, Borges, Fernanda, Cordeiro, M. Natália D. S, Cagide Fajin, J. Luis, Morell, Carlos, Ruiz, Reinaldo Molina, Cañizares-Carmenate, Yudith, Dominguez, Elena Rosa

“…Up to now, very few applications of multiobjective optimization (MOOP) techniques to quantitative structure−activity relationship (QSAR) studies have been…”
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Predicting the affinity of A2A adenosine receptor antagonists using decision trees by Adonis Huici Corrales, Aliuska Morales Helguera, Evys Ancede Gallardo Ancede Gallardo, Reinaldo Molina Ruiz, Marta Teijeira Bautista, Guillermo Abreu Stincer, Eugenio Martínez Albelo

“…Neurodegenerative diseases are being treated by modulating adenosine receptors with more effective, safe and selective antagonists. The objective of the study…”
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TI2BioP: Topological Indices to BioPolymers. Its practical use to unravel cryptic bacteriocin-like domains by Agüero-Chapin, Guillermín, Pérez-Machado, Gisselle, Molina-Ruiz, Reinaldo, Pérez-Castillo, Yunierkis, Morales-Helguera, Aliuska, Vasconcelos, Vítor, Antunes, Agostinho

“…Bacteriocins are proteinaceous toxins produced and exported by both gram-negative and gram-positive bacteria as a defense mechanism. The bacteriocin protein…”
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Non-linear models based on simple topological indices to identify RNase III protein members by Agüero-Chapin, Guillermin, de la Riva, Gustavo A, Molina-Ruiz, Reinaldo, Sánchez-Rodríguez, Aminael, Pérez-Machado, Gisselle, Vasconcelos, Vítor, Antunes, Agostinho

“…Alignment-free classifiers are especially useful in the functional classification of protein classes with variable homology and different domain structures…”
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Theoretical Prediction of Antiproliferative Activity against Murine Leukemia Tumor Cell Line (L1210). 3D‐Morse Descriptor and its Application in Computational Chemistry by Saíz‐Urra, Liane, Pérez‐Castillo, Yunierkis, Pérez González, Maykel, Molina Ruiz, Reinaldo, Cordeiro, M. Natália D. S., Rodríguez‐Borges, J. Enrique, García‐Mera, Xerardo

“…Cancer is among the top ten causes of death in the world but in spite of the efforts of the pharmaceutical companies and many governmental organizations, new…”
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A TOPological Sub-structural Molecular Design (TOPS-MODE)-QSAR approach for modeling the antiproliferative activity against murine leukemia tumor cell line (L1210) by Molina-Ruiz, Reinaldo, Saíz-Urra, Liane, Rodríguez-Borges, J.E., Pérez-Castillo, Yunierkis, González, Maykel Pérez, García-Mera, Xerardo, Cordeiro, M. Natália D.S.

“…Lately, Quantitative Structure–Activity Relationship (QSAR) studies have been afar used to predict anticancer activity taking into account different molecular…”
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