Search Results - "Ruiz, Jeronimo Conceição"

Microfluidics and organ-on-a-chip technologies: A systematic review of the methods used to mimic bone marrow by Santos Rosalem, Gabriel, Gonzáles Torres, Libardo Andrés, de Las Casas, Estevam Barbosa, Mathias, Fernando Augusto Siqueira, Ruiz, Jeronimo Conceição, Carvalho, Maria Gabriela Reis

“…Bone marrow (BM) is an organ responsible for crucial processes in living organs, e. g., hematopoiesis. In recent years, Organ-on-a-Chip (OoC) devices have been…”
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A chimeric vaccine combined with adjuvant system induces immunogenicity and protection against visceral leishmaniasis in BALB/c mice by Ostolin, Thais Lopes Valentim Di Paschoale, Gusmão, Miriã Rodrigues, Mathias, Fernando Augusto Siqueira, Cardoso, Jamille Mirelle de Oliveira, Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Ruiz, Jeronimo Conceição, Resende, Daniela de Melo, de Brito, Rory Cristiane Fortes, Reis, Alexandre Barbosa

“…In Brazil, canine visceral leishmaniasis is an important public health problem due to its alarming growth. The high prevalence of infected dogs reinforces the…”
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Transcriptomic analysis of benznidazole-resistant and susceptible Trypanosoma cruzi populations by Lima, Davi Alvarenga, Gonçalves, Leilane Oliveira, Reis-Cunha, João Luís, Guimarães, Paul Anderson Souza, Ruiz, Jeronimo Conceição, Liarte, Daniel Barbosa, Murta, Silvane Maria Fonseca

“…Chagas disease (CD), caused by the parasite Trypanosoma cruzi, is a serious public health concern in Latin America. Nifurtimox and benznidazole (BZ), the only…”
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Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles by Bayer-Santos, Ethel, Lima, Fábio Mitsuo, Ruiz, Jeronimo Conceição, Almeida, Igor C., da Silveira, José Franco

“…•The small RNAs contained in vesicles originate from multiple sources.•Results revealed differences in the variety of small RNAs between parasite stages.•The…”
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Perspectives From Systems Biology to Improve Knowledge of Leishmania Drug Resistance by Horácio, Elvira Cynthia Alves, Hickson, Jéssica, Murta, Silvane Maria Fonseca, Ruiz, Jeronimo Conceição, Nahum, Laila Alves

“…Neglected Tropical Diseases include a broad range of pathogens, hosts, and vectors, which represent evolving complex systems. Leishmaniasis, caused by…”
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TriatoKey: a web and mobile tool for biodiversity identification of Brazilian triatomine species by Márcia de Oliveira, Luciana, Nogueira de Brito, Raissa, Anderson Souza Guimarães, Paul, Vitor Mastrângelo Amaro dos Santos, Rômulo, Gonçalves Diotaiuti, Liléia, de Cássia Moreira de Souza, Rita, Conceição Ruiz, Jeronimo

“…Abstract Triatomines are blood-sucking insects that transmit the causative agent of Chagas disease, Trypanosoma cruzi. Despite being recognized as a difficult…”
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Hypervirulence and cross-resistance to a clinical antifungal are induced by an environmental fungicide in Cryptococcus gattii by Carneiro, Hellem Cristina Silva, Bastos, Rafael Wesley, Ribeiro, Noelly Queiroz, Gouveia-Eufrasio, Ludmila, Costa, Marliete Carvalho, Magalhães, Thais Furtado Ferreira, Oliveira, Lorena Vívien Neves, Paixão, Tatiane Alves, Joffe, Luna Sobrino, Rodrigues, Marcio L., Araújo, Glauber Ribeiro de Sousa, Frases, Susana, Ruiz, Jeronimo Conceição, Marinho, Paula, Abrahão, Jônatas Santos, Resende-Stoianoff, Maria Aparecida, Carter, Dee, Santos, Daniel Assis

“…The increasing human population requires ongoing efforts in food production. This is frequently associated with an increased use of agrochemicals, leading to…”
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Proteomic analysis reveals differentially abundant proteins probably involved in the virulence of amastigote and promastigote forms of Leishmania infantum by Fialho Junior, Luiz, da Fonseca Pires, Simone, Burchmore, Richard, McGill, Suzanne, Weidt, Stefan, Ruiz, Jeronimo Conceição, Guimarães, Frederico Goncalves, Chapeourouge, Alexander, Perales, Jonas, de Andrade, Hélida Monteiro

“…Owing to the importance and clinical diversity of Leishmania infantum , studying its virulence factors is promising for understanding the relationship between…”
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A specific Leishmania infantum polyepitope vaccine triggers Th1-type immune response and protects against experimental visceral leishmaniasis by Lopes Valentim Di Paschoale Ostolin, Thais, Rodrigues Gusmão, Miriã, Augusto Siqueira Mathias, Fernando, Mirelle de Oliveira Cardoso, Jamille, Mendes Roatt, Bruno, Dian de Oliveira Aguiar-Soares, Rodrigo, Conceição Ruiz, Jeronimo, de Melo Resende, Daniela, Cristiane Fortes de Brito, Rory, Barbosa Reis, Alexandre

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Diversity and genome mapping assessment of disordered and functional domains in trypanosomatids by Avelar, Grace Santos Tavares, Gonçalves, Leilane Oliveira, Guimarães, Frederico Gonçalves, Guimarães, Paul Anderson Souza, do Nascimento Rocha, Luiz Gustavo, Carvalho, Maria Gabriela Reis, de Melo Resende, Daniela, Ruiz, Jeronimo Conceição

“…The proteins that have structural disorder exemplify a class of proteins which is part of a new frontier in structural biology that demands a new understanding…”
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Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines by Andrade, Juvana Moreira, Gonçalves, Leilane Oliveira, Liarte, Daniel Barbosa, Lima, Davi Alvarenga, Guimarães, Frederico Gonçalves, de Melo Resende, Daniela, Santi, Ana Maria Murta, de Oliveira, Luciana Marcia, Velloso, João Paulo Linhares, Delfino, Renato Guimarães, Pescher, Pascale, Späth, Gerald F, Ruiz, Jeronimo Conceição, Murta, Silvane Maria Fonseca, Velloso, Joao Paulo, Delfino, Renato Guimaraes, Spath, Gerald F, Ruiz, Jeronimo Conceicao

“…One of the major challenges to leishmaniasis treatment is the emergence of parasites resistant to antimony. To study differentially expressed genes associated…”
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Tumor Neoepitope-Based Vaccines: A Scoping Review on Current Predictive Computational Strategies by Rocha, Luiz Gustavo do Nascimento, Guimarães, Paul Anderson Souza, Carvalho, Maria Gabriela Reis, Ruiz, Jeronimo Conceição

“…Therapeutic cancer vaccines have been considered in recent decades as important immunotherapeutic strategies capable of leading to tumor regression. In the…”
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Identification and characterization of microsatellite markers for population genetic studies of Panstrongylus megistus (Burmeister, 1835) (Triatominae: Reduviidae) by Ferreira, Flávio Campos, Gonçalves, Leilane Oliveira, Ruiz, Jeronimo Conceição, Koerich, Leonardo Barbosa, Pais, Fabiano Sviatopolk Mirsky, Diotaiuti, Lileia Gonçalves, Belisário, Carlota Josefovicz

“…Panstrongylus megistus is the most important vector of Chagas disease in Brazil. Studies show that the principal factor hindering the control of triatomines is…”
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Genome size, karyotype polymorphism and chromosomal evolution in Trypanosoma cruzi by Souza, Renata T, Lima, Fábio M, Barros, Roberto Moraes, Cortez, Danielle R, Santos, Michele F, Cordero, Esteban M, Ruiz, Jeronimo Conceiçao, Goldenberg, Samuel, Teixeira, Marta M G, da Silveira, José Franco

“…The Trypanosoma cruzi genome was sequenced from a hybrid strain (CL Brener). However, high allelic variation and the repetitive nature of the genome have…”
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Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T Cells That Trigger Protection against Experimental Visceral Leishmaniasis by Brito, Rory Cristiane Fortes De, Ruiz, Jeronimo Conceição, Cardoso, Jamille Mirelle de Oliveira, Ostolin, Thais Lopes Valentim Di Paschoale, Reis, Levi Eduardo Soares, Mathias, Fernando Augusto Siqueira, Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Corrêa-Oliveira, Rodrigo, Resende, Daniela de Melo, Reis, Alexandre Barbosa

“…Many vaccine candidates against visceral leishmaniasis (VL) have been proposed; however, to date, none of them have been efficacious for the human or canine…”
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Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice by De Brito, Rory Cristiane Fortes, Cardoso, Jamille Mirelle de Oliveira, Reis, Levi Eduardo Soares, Mathias, Fernando Augusto Siqueira, Aguiar-Soares, Rodrigo Dian de Oliveira, Teixeira-Carvalho, Andréa, Roatt, Bruno Mendes, Corrêa-Oliveira, Rodrigo, Ruiz, Jeronimo Conceição, Resende, Daniela de Melo, Reis, Alexandre Barbosa

“…Reverse vaccinology or immunoinformatics is a computational methodology which integrates data from in silico epitope prediction, associated to other important…”
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Identification and characterization of expressed retrotransposons in the genome of the Paracoccidioides species complex by Soares, Marco Aurélio, de Carvalho Araújo, Roberta Amália, Marini, Marjorie Mendes, de Oliveira, Luciana Márcia, de Lima, Leonardo Gomes, de Souza Alves, Viviane, Felipe, Maria Sueli Soares, Brigido, Marcelo Macedo, de Almeida Soares, Celia Maria, da Silveira, Jose Franco, Ruiz, Jeronimo Conceição, Cisalpino, Patrícia Silva

“…Species from the Paracoccidioides complex are thermally dimorphic fungi and the causative agents of paracoccidioidomycosis, a deep fungal infection that is the…”
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The level of ascorbate peroxidase is enhanced in benznidazole-resistant populations of Trypanosoma cruzi and its expression is modulated by stress generated by hydrogen peroxide by Nogueira, Fernanda Barbosa, Rodrigues, Joyce Fernanda A, Correa, Marcos Messias S, Ruiz, Jerônimo Conceição, Romanha, Alvaro José, Murta, Silvane Maria Fonseca

“…Ascorbate peroxidases (APX) are class I heme-containing enzymes that convert hydrogen peroxide into water molecules. The gene encoding APX has been…”
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In silico analysis of putative dormancy genes in Plasmodium vivax by de Souza Ribeiro, Ricardo, de Melo Resende, Daniela, Ruiz, Jerônimo Conceição, Ferreira Alves de Brito, Cristiana

“…[Display omitted] •Mauritanian I and North Korean are the highest diverse P. vivax genomes.•Selected putative dormancy genes are conserved and under purifying…”
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Intrinsically disordered proteins (IDPs) in trypanosomatids by de Cássia Ruy, Patrícia, Torrieri, Raul, Toledo, Juliano Simões, de Souza Alves, Viviane, Cruz, Angela Kaysel, Ruiz, Jeronimo Conceição

“…Proteins are composed of one or more amino acid chains and exhibit several structure levels. IDPs (intrinsically disordered proteins) represent a class of…”
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