Search Results - "Ruiz, Amalia"
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A Biodegradable Multifunctional Graphene Oxide Platform for Targeted Cancer Therapy
Published in Advanced functional materials (01-09-2019)“…The design of multifunctional materials able to both selectively deliver a drug into cells in a targeted manner and display an enhanced propensity for…”
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Co-Loading of Black Phosphorus Nanoflakes and Doxorubicin in Lysolipid Temperature-Sensitive Liposomes for Combination Therapy in Prostate Cancer
Published in International journal of molecular sciences (21-12-2023)“…Black phosphorus (BP) is one of the most promising nanomaterials for cancer therapy. This 2D material is biocompatible and has strong photocatalytic activity,…”
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3
Giant Cell Tumor of the Triquetrum: Clinical Case and Literature Review
Published in Hand (New York, N.Y.) (01-11-2022)“…Giant cell tumor (GCT) is a benign, locally aggressive neoplasm with little incidence at the carpal bone level. We present a case of pyramidal bone GCT that…”
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The Deubiquitinase OTUB1 Is a Key Regulator of Energy Metabolism
Published in International journal of molecular sciences (28-01-2022)“…Dysregulated energy metabolism is a major contributor to a multitude of pathologies, including obesity and diabetes. Understanding the regulation of metabolic…”
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Understanding the Influence of a Bifunctional Polyethylene Glycol Derivative in Protein Corona Formation around Iron Oxide Nanoparticles
Published in Materials (10-07-2019)“…Superparamagnetic iron oxide nanoparticles are one of the most prominent agents used in theranostic applications, with MRI imaging the main application…”
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Encapsulation and Delivery of Mitoxantrone Using Zirconium-Based Metal–Organic Frameworks (MOFs) and Their Cytotoxic Potential in Breast Cancer Cells
Published in Applied sciences (01-02-2024)“…Mitoxantrone (MTX) is a drug employed in breast cancer treatment, but its application is largely limited due to side effects. A controlled delivery approach…”
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7
Anomalous insertion of the pectoralis minor tendon at the greater tuberosity
Published in Journal of ultrasound (01-09-2020)“…We present a case of ectopic insertion of the whole tendon of the pectoralis minor muscle associated with impingement syndrome. Based on this case, we…”
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Light-Responsive and Antibacterial Graphenic Materials as a Holistic Approach to Tissue Engineering
Published in ACS Nanoscience Au (21-08-2024)“…While the continuous development of advanced bioprinting technologies is under fervent study, enhancing the regenerative potential of hydrogel-based constructs…”
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Oxygen-dependent bond formation with FIH regulates the activity of the client protein OTUB1
Published in Redox biology (01-09-2019)“…Protein:protein interactions are the basis of molecular communication and are usually of transient non-covalent nature, while covalent interactions other than…”
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OTUB1 regulates lung development, adult lung tissue homeostasis, and respiratory control
Published in The FASEB journal (01-12-2021)“…OTUB1 is one of the most highly expressed deubiquitinases, counter‐regulating the two most abundant ubiquitin chain types. OTUB1 expression is linked to the…”
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“Ultramixing”: A Simple and Effective Method To Obtain Controlled and Stable Dispersions of Graphene Oxide in Cell Culture Media
Published in ACS applied materials & interfaces (27-02-2019)“…The last decade has seen an increase in the application of graphene oxide (GO) in the biomedical field. GO has been successfully exploited for its ability to…”
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Toxicological evaluation of highly water dispersible few-layer graphene in vivo
Published in Carbon (New York) (01-12-2020)“…In the last decade, graphene-based materials have received increasing attention for both academic research and industrial uses. However, products containing…”
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Oriented Attachment of Recombinant Proteins to Agarose-Coated Magnetic Nanoparticles by Means of a β‑Trefoil Lectin Domain
Published in Bioconjugate chemistry (16-11-2016)“…Design of generic methods aimed at the oriented attachment of proteins at the interfacial environment of magnetic nanoparticles currently represents an active…”
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Genetically-engineered anti-PSMA exosome mimetics targeting advanced prostate cancer in vitro and in vivo
Published in Journal of controlled release (10-02-2021)“…The present work describes the engineering of anti-PSMA peptide-decorated exosome mimetics (EMs) targeting advanced prostate cancer (PC). The targeted EMs were…”
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Encapsulated doxorubicin crystals influence lysolipid temperature-sensitive liposomes release and therapeutic efficacy in vitro and in vivo
Published in Journal of controlled release (10-12-2020)“…Doxorubicin (DOX)-loaded lysolipid temperature-sensitive liposomes (LTSLs) are a promising stimuli-responsive drug delivery system that rapidly releases DOX in…”
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Hypoxia-targeted cupric-tirapazamine liposomes potentiate radiotherapy in prostate cancer spheroids
Published in International journal of pharmaceutics (25-09-2021)“…[Display omitted] In this study, novel cupric-tirapazamine [Cu(TPZ)2]-liposomes were developed as an effective hypoxia-targeted therapeutic, which potentiated…”
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Oligo(styryl)benzenes liposomal AIE-dots for bioimaging and phototherapy in an in vitro model of prostate cancer
Published in Journal of colloid and interface science (15-09-2024)“…[Display omitted] Whilst the development of advanced organic dots with aggregation-induced emission characteristics (AIE-dots) is being intensively studied,…”
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EGFR-targeted immunoliposomes efficiently deliver docetaxel to prostate cancer cells
Published in Colloids and surfaces, B, Biointerfaces (01-10-2020)“…[Display omitted] •Docetaxel was encapsulated into anti-EGFR immunoliposomes.•The formulation was nanosized, with high drug encapsulation and controlled…”
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Does black phosphorus hold potential to overcome graphene oxide? A comparative review of their promising application for cancer therapy
Published in Nanoscale advances (13-07-2021)“…Although graphene oxide (GO) is leading the way in the biomedical field of 2D materials, nanosized black phosphorus (NBP) has recently come to attention for…”
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Engineering PSMA-targeted nanoparticles co-encapsulating mitoxantrone and indocyanine green for precise combinatory therapy in prostate cancer
Published in Journal of drug delivery science and technology (01-12-2024)“…Prostate cancer is the 2nd most common cancer in men worldwide. Chemotherapeutic treatment of prostate cancer with mitoxantrone (MTX) has limited efficacy due…”
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