Search Results - "Ruiter, Floor A.A."
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Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition
Published in Biomaterials (01-08-2021)“…Differentiated kidney organoids from induced pluripotent stem cells hold promise as a treatment for patients with kidney diseases. Before these organoids can…”
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Molecular Tuning of a Benzene‐1,3,5‐Tricarboxamide Supramolecular Fibrous Hydrogel Enables Control over Viscoelasticity and Creates Tunable ECM‐Mimetic Hydrogels and Bioinks
Published in Advanced materials (Weinheim) (01-06-2023)“…Traditional synthetic covalent hydrogels lack the native tissue dynamics and hierarchical fibrous structure found in the extracellular matrix (ECM). These…”
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In Situ Covalent Reinforcement of a Benzene‐1,3,5‐Tricarboxamide Supramolecular Polymer Enables Biomimetic, Tough, and Fibrous Hydrogels and Bioinks
Published in Advanced materials (Weinheim) (01-09-2023)“…Synthetic hydrogels often lack the load‐bearing capacity and mechanical properties of native biopolymers found in tissue, such as cartilage. In natural…”
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Optimization of Media Change Intervals through Hydrogels Using Mathematical Models
Published in Biomacromolecules (13-02-2023)“…Three-dimensional cell culture in engineered hydrogels is increasingly used in tissue engineering and regenerative medicine. The transfer of nutrients, gases,…”
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Soft, Dynamic Hydrogel Confinement Improves Kidney Organoid Lumen Morphology and Reduces Epithelial–Mesenchymal Transition in Culture
Published in Advanced science (01-07-2022)“…Pluripotent stem cell‐derived kidney organoids offer a promising solution to renal failure, yet current organoid protocols often lead to off‐target cells and…”
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Modular mixing of benzene-1,3,5-tricarboxamide supramolecular hydrogelators allows tunable biomimetic hydrogels for control of cell aggregation in 3D
Published in Biomaterials science (24-08-2022)“…Few synthetic hydrogels can mimic both the viscoelasticity and supramolecular fibrous structure found in the naturally occurring extracellular matrix (ECM)…”
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