Search Results - "Ruijter, Hester M Den"

Sex-dependent gene co-expression in the human body by Hartman, Robin J. G., Mokry, Michal, Pasterkamp, Gerard, den Ruijter, Hester M.

“…Many pathophysiological mechanisms in human health and disease are dependent on sex. Systems biology approaches are successfully used to decipher human disease…”
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X chromosome inactivation skewing is common in advanced carotid atherosclerotic lesions in females and predicts secondary peripheral artery events by Buono, Michele F, Benavente, Ernest Diez, Daniels, Mark, Mol, Barend M, Mekke, Joost M, de Borst, Gert J, de Kleijn, Dominique P V, van der Laan, Sander W, Pasterkamp, Gerard, Onland-Moret, Charlotte, Mokry, Michal, den Ruijter, Hester M

“…Sex differences in atherosclerosis have been described with female plaques being mostly perceived as stable and fibrous. Sex-specific mechanisms such as mosaic…”
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Improvements in risk stratification for the occurrence of cardiovascular disease by imaging subclinical atherosclerosis: a systematic review by Peters, Sanne A E, den Ruijter, Hester M, Bots, Michiel L, Moons, Karel G M

“…Imaging for subclinical atherosclerosis on top of conventional risk factor assessment may improve risk prediction for the occurrence of cardiovascular disease…”
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Intrinsic transcriptomic sex differences in human endothelial cells at birth and in adults are associated with coronary artery disease targets by Hartman, Robin J. G., Kapteijn, Daniek M. C., Haitjema, Saskia, Bekker, Mireille N., Mokry, Michal, Pasterkamp, Gerard, Civelek, Mete, den Ruijter, Hester M.

“…Sex differences in endothelial cell (EC) biology may reflect intrinsic differences driven by chromosomes or sex steroid exposure and gender differences…”
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High reproducibility of histological characterization by whole virtual slide quantification; an example using carotid plaque specimens by Vrijenhoek, Joyce E P, Nelissen, Bastiaan G L, Velema, Evelyn, Vons, Kristy, de Vries, Jean-Paul P M, Eijkemans, Marinus J C, den Ruijter, Hester M, de Borst, Gert Jan, Moll, Frans L, Pasterkamp, Gerard

“…Tissue biobanks are an important source for discovery and validation studies aiming for new proteins that are causally related with disease development. There…”
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Simplification of a registry-based algorithm for ejection fraction prediction in heart failure patients: Applicability in cardiology centres of the Netherlands by Canto, Elisa Dal, Uijl, Alicia, Onland-Moret, N. Charlotte, Bots, Sophie H, Hofstra, Leonard, Tulevski, Igor, Asselbergs, Folkert W, van der Harst, Pim, Somsen, G. Aernout, den Ruijter, Hester M

“…Background Left ventricular ejection fraction (EF) is used to categorize heart failure (HF) into phenotypes but this information is often missing in electronic…”
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Cardiac Magnetic Resonance Imaging Findings and the Risk of Cardiovascular Events in Patients With Recent Myocardial Infarction or Suspected or Known Coronary Artery Disease by El Aidi, Hamza, MD, Adams, Arthur, MD, Moons, Karel G.M., MD, PhD, Den Ruijter, Hester M., PhD, Mali, Willem P.Th.M., MD, PhD, Doevendans, Pieter A., MD, PhD, Nagel, Eike, PhD, Schalla, Simon, MD, PhD, Bots, Michiel L., MD, PhD, Leiner, Tim, MD, PhD

“…The goal of this study was to review the prognostic value of cardiac magnetic resonance (CMR) imaging findings for future cardiovascular events in patients…”
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Estrogen and Cardiovascular Health by den Ruijter, Hester M, Kararigas, Georgios

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Editor's Choice – Predictors of New Ischaemic Brain Lesions on Diffusion Weighted Imaging After Carotid Stenting and Endarterectomy: A Systematic Review by Rots, Marjolijn L., Meershoek, Armelle J.A., Bonati, Leo H., den Ruijter, Hester M., de Borst, Gert J.

“…Peri-procedural ischaemic brain lesions on diffusion weighted imaging (DWI) after carotid endarterectomy (CEA) and carotid artery stenting (CAS) have been…”
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Diabetes and risk of acute coronary syndrome in callers with chest discomfort: Cross-sectional study in out-of-hours primary care by Spek, Michelle, Erkelens, Daphne C.A., van het Goor – van Wezep, Coralie, van Smeden, Maarten, Den Ruijter, Hester M., Wouters, Loes T.C.M., Venekamp, Roderick P., Rutten, Frans H., Zwart, Dorien L.

“…[Display omitted] •It has been suggested that patients with diabetes who experience an ACS present with a broad variety of symptoms which could hamper the…”
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Loss of Y Chromosome in Blood Is Associated With Major Cardiovascular Events During Follow-Up in Men After Carotid Endarterectomy by Haitjema, Saskia, Kofink, Daniel, van Setten, Jessica, van der Laan, Sander W, Schoneveld, Arjan H, Eales, James, Tomaszewski, Maciej, de Jager, Saskia C.A, Pasterkamp, Gerard, Asselbergs, Folkert W, den Ruijter, Hester M

“…BACKGROUND—Recent studies found an immune regulatory role for Y chromosome and a relationship between loss of Y chromosome (LOY) in blood cells and a higher…”
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Family history and polygenic risk of cardiovascular disease: Independent factors associated with secondary cardiovascular events in patients undergoing carotid endarterectomy by Timmerman, Nathalie, de Kleijn, Dominique P.V., de Borst, Gert J., den Ruijter, Hester M., Asselbergs, Folkert W., Pasterkamp, Gerard, Haitjema, Saskia, van der Laan, Sander W.

“…Family history (FHx) of cardiovascular disease (CVD) is a risk factor for CVD and a proxy for cardiovascular heritability. Polygenic risk scores (PRS)…”
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Fair inclusion of pregnant women in clinical trials: an integrated scientific and ethical approach by van der Graaf, Rieke, van der Zande, Indira S E, den Ruijter, Hester M, Oudijk, Martijn A, van Delden, Johannes J M, Oude Rengerink, Katrien, Groenwold, Rolf H H

“…Since pregnant women are severely underrepresented in clinical research, many take the position that the exclusion of pregnant women from research must be…”
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Sex differences in cardiovascular epigenetics-a systematic review by Hartman, Robin J G, Huisman, Sarah E, den Ruijter, Hester M

“…Differences in cardiovascular diseases are evident in men and women throughout life and are mainly attributed to the presence of sex hormones and chromosomes…”
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Estrogen Contributions to Microvascular Dysfunction Evolving to Heart Failure With Preserved Ejection Fraction by Sickinghe, Ariane A, Korporaal, Suzanne J A, den Ruijter, Hester M, Kessler, Elise L

“…Heart failure with preserved ejection fraction (HFpEF) is a syndrome involving microvascular dysfunction. No treatment is available yet and as the HFpEF…”
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Ten Years of High-Sensitivity Cardiac Troponin Testing: Impact on the Diagnosis of Myocardial Infarction by Kimenai, Dorien M, Appelman, Yolande, den Ruijter, Hester M, Shah, Anoop S V, Mills, Nicholas L, Meex, Steven J R

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Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort by Zhang, Ya-Nan, Vernooij, Flora, Ibrahim, Irwani, Ooi, Shirley, Gijsberts, Crystel M, Schoneveld, Arjan H, Sen, Kuan Win, den Ruijter, Hester M, Timmers, Leo, Richards, Arthur Mark, Jong, Chun Tzen, Mazlan, Ibrahim, Wang, Jiong-Wei, Lam, Carolyn S P, de Kleijn, Dominique P V

“…SerpinF2, SerpinG1, CystatinC and CD14 are involved in inflammatory processes and plasma extracellular vesicle (EV) -levels of these proteins have been…”
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Time-Dependent Changes in Atherosclerotic Plaque Composition in Patients Undergoing Carotid Surgery by van Lammeren, Guus W, den Ruijter, Hester M, Vrijenhoek, Joyce E P, van der Laan, Sander W, Velema, Evelyn, de Vries, Jean-Paul P M, de Kleijn, Dominique P V, Vink, Aryan, de Borst, Gert Jan, Moll, Frans L, Bots, Michiel L, Pasterkamp, Gerard

“…BACKGROUND—Time-dependent trends in the incidence of cardiovascular disease have been reported in high-income countries. Because atherosclerosis underlies the…”
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Effect of Monocyte-to-Lymphocyte Ratio on Heart Failure Characteristics and Hospitalizations in a Coronary Angiography Cohort by Gijsberts, Crystel M., Ellenbroek, Guilielmus H.J.M., ten Berg, Maarten J., Huisman, Albert, van Solinge, Wouter W., Lam, Carolyn S., Asselbergs, Folkert W., den Ruijter, Hester M., Pasterkamp, Gerard, Hoefer, Imo E., de Kleijn, Dominique P.

“…Inflammation is a shared mechanism in coronary artery disease (CAD) and subsequent heart failure (HF), and circulating monocyte and lymphocyte counts predict…”
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Sex-specific microRNAs in women with diabetes and left ventricular diastolic dysfunction or HFpEF associate with microvascular injury by Florijn, Barend W., Valstar, Gideon B., Duijs, Jacques M. G. J., Menken, Roxana, Cramer, Maarten J., Teske, Arco J., Ghossein-Doha, Chahinda, Rutten, Frans H., Spaanderman, Marc E. A., den Ruijter, Hester M., Bijkerk, Roel, van Zonneveld, Anton Jan

“…Left ventricular diastolic dysfunction (LVDD) and heart failure with preserved ejection fraction (HFpEF) are microcirculation defects following diabetes…”
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