Search Results - "Rugo, R. E."

Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo by KOTURBASH, I, RUGO, R. E, HENDRICKS, C. A, LOREE, J, THIBAULT, B, KUTANZI, K, POGRIBNY, I, YANCH, J. C, ENGELWARD, B. P, KOVALCHUK, O

“…Irradiated cells induce chromosomal instability in unirradiated bystander cells in vitro. Although bystander effects are thought to be linked to…”
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Methyltransferases mediate cell memory of a genotoxic insult by Rugo, R E, Mutamba, J T, Mohan, K N, Yee, T, Chaillet, J R, Greenberger, J S, Engelward, B P

“…Characterization of the direct effects of DNA-damaging agents shows how DNA lesions lead to specific mutations. Yet, serum from Hiroshima survivors, Chernobyl…”
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X Radiation Causes a Persistent Induction of Reactive Oxygen Species and a Delayed Reinduction of TP53 in Normal Human Diploid Fibroblasts by Rugo, R. E., Secretan, M. B., Schiestl, R. H.

“…Rugo, R. E., Secretan, M. B. and Schiestl, R. H. X Radiation Causes a Persistent Induction of Reactive Oxygen Species and a Delayed Reinduction of TP53 in…”
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A single acute exposure to a chemotherapeutic agent induces hyper-recombination in distantly descendant cells and in their neighbors by RUGO, Rebecca E, ALMEIDA, Karen H, HENDRICKS, Carrie A, JONNALAGADDA, Vidya S, ENGELWARD, Bevin P

“…Homologous recombination can induce tumorigenic sequence rearrangements. Here, we show that persistent hyper-recombination can be induced following exposure to…”
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Spontaneous Mitotic Homologous Recombination at an Enhanced Yellow Fluorescent Protein (EYFP) cDNA Direct Repeat in Transgenic Mice by Hendricks, Carrie A., Almeida, Karen H., Stitt, Molly S., Jonnalagadda, Vidya S., Rugo, Rebecca E., Kerrison, G. Foster, Engelward, Bevin P.

“…A transgenic mouse has been created that provides a powerful tool for revealing genetic and environmental factors that modulate mitotic homologous…”
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Increases in Oxidative Stress in the Progeny of X-Irradiated Cells by Rugo, R E, Schiestl, R H

“…A number of phenotypes persist in the progeny of irradiated cells for many generations including delayed reproductive death, cell transformation, genomic…”
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Tissue-specific differences in the accumulation of sequence rearrangements with age by Wiktor-Brown, Dominika M., Olipitz, Werner, Hendricks, Carrie A., Rugo, Rebecca E., Engelward, Bevin P.

“…Mitotic homologous recombination (HR) is a critical pathway for the accurate repair of DNA double strand breaks (DSBs) and broken replication forks. While…”
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X Radiation Causes a Persistent Induction of Reactive Oxygen Species and a Delayed Reinduction of TP53 in Normal Human Diploid Fibroblasts by Rugo, R E, Secretan, M B, Schiestl, R

“…Multiple genetic changes are required for the development of a malignant cell. The frequency of such changes in cancer cells is higher than can be explained…”
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Increases in Oxidative Stress in the Progeny of X-Irradiated Cells by Rugo, Rebecca E., Schiestl, Robert H.

“…Rugo, R. E. and Schiestl, R. H. Increases in Oxidative Stress in the Progeny of X-Irradiated Cells. Radiat. Res. 162, 416– 425 (2004). A number of phenotypes…”
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