Search Results - "Ruggles, D.I."

Developmental effects of serum from flaxseed-fed rats on cultured rat embryos by Flynn, T.J., Collins, T.F.X., Sprando, R.L., Black, T.N., Ruggles, D.I., Wiesenfeld, P.W., Babu, U.S.

“…Gestation day 9.5 rat embryos were cultured for 45 h in serum obtained from pregnant rats that had been fed throughout gestation with either a control diet…”
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Effects of fumonisin B1 in pregnant rats. Part 2 by COLLINS, T. F. X, SPRANDO, R. L, RUGGLES, D. I, OLEJNIK, N, RORIE, J. I, BLACK, T. N, SHACKELFORD, M. E, LABORDE, J. B, HANSEN, D. K, EPPLEY, R. M, TRUCKSESS, M. W, HOWARD, P. C, BRYANT, M. A

“…The developmental toxicity of purified fumonisin B1 (FB1), a mycotoxin from the common corn fungus Fusarium moniliforme, was examined in Charles River rats…”
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Developmental toxicity of sodium fluoride in rats by Collins, T.F.X., Sprando, R.L., Shackelford, M.E., Black, T.N., Ames, M.J., Welsh, J.J., Balmer, M.F., Olejnik, N., Ruggles, D.I.

“…Despite the chronic exposure of the US population to fluoridated drinking water since the 1940s, existing studies have been judged inadequate to determine any…”
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A study of the teratogenic potential of caffeine ingested in drinking-water by Collins, T F, Welsh, J J, Black, T N, Ruggles, D I

“…Caffeine dissolved in drinking-water was available ad lib. to Osborne-Mendel rats at dose levels of 0, 0.007, 0.018, 0.036, 0.07, 0.10, 0.15 or 0.20% during…”
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Prooxidant activity and toxicity of nordihydroguaiaretic acid in clone-9 rat hepatocyte cultures by Sahu, Saura C., Ruggles, Dennis I., O’Donnell, Michael W.

“…Nordihydroguaiaretic acid (NDGA) is a polyphenol. It is present at high concentrations in the leaves of the evergreen desert shrub, Larrea tridentate (Creosote…”
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Characterization of the effect of deoxynivalenol on selected male reproductive endpoints by Sprando, Robert L., Collins, Thomas F.X., Black, Thomas N., Olejnik, Nicholas, Rorie, James I., Eppley, Robert M., Ruggles, Dennis I.

“…The effect of deoxynivalenol (DON) exposure on male reproductive function was assessed in the rat. Male rats were divided into a control group ( n = 15 rats)…”
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Effects of deoxynivalenol (DON, vomitoxin) on in utero development in rats by Collins, Thomas F.X., Sprando, Robert L., Black, Thomas N., Olejnik, Nicholas, Eppley, Robert M., Hines, Fred A., Rorie, James, Ruggles, Dennis I.

“…Deoxynivalenol (DON, vomitoxin), is one of the most common contaminants of cereal grains world-wide. The effects of DON on fetal development were assessed in…”
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Effects of aminopentol on in utero development in rats by Collins, Thomas F.X., Sprando, Robert L., Black, Thomas N., Olejnik, Nicholas, Eppley, Robert M., Shackelford, Mary E., Howard, Paul C., Rorie, James I., Bryant, Mark, Ruggles, Dennis I.

“…Aminopentol (AP1), the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), is present in corn-based foods which are consumed daily as a…”
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Effects of flaxseed and defatted flaxseed meal on reproduction and development in rats by Collins, Thomas F.X, Sprando, Robert L, Black, Thomas N, Olejnik, Nicholas, Wiesenfeld, Paddy W, Babu, Uma S, Bryant, Mark, Flynn, Thomas J, Ruggles, Dennis I

“…Flaxseed, a rich source of reportedly beneficial n-3 fatty acid and phytoestrogens, has not been thoroughly tested for reproductive effects. High levels of…”
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Maternal exposure to androstenedione does not induce developmental toxicity in the rat by Sprando, Robert L., Collins, Thomas F.X., Black, Thomas N., Olejnik, Nicholas, Sapienza, Philip, Ramos-Valle, Moraima, Ruggles, Dennis I.

“…Thirty-day old female rats received corn oil or androstenedione (in corn oil) at one of four concentrations (5.0, 10.0, 30.0 or 60.0 mg/kg body weight) by…”
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Developmental toxicity of sodium fluoride measured during multiple generations by Collins, T.F.X, Sprando, R.L, Black, T.N, Shackelford, M.E, Olejnik, N, Ames, M.J, Rorie, J.I, Ruggles, D.I

“…Sodium fluoride (NaF) has been used to fluoridate drinking water in the United States since the mid 1940s. Because of the lack of reliable studies on the…”
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Multigenerational evaluation of sodium fluoride in rats by Collins, T.F.X., Sprando, RL, Black, T.N., Shackelford, M.E., Bryant, M.A., Olejnik, N., Ames, M.J., Rorie, J.I., Ruggles, D.I.

“…Since the mid 1940s, fluoride has been added to tap water in American communities in an effort to reduce the incidence of dental caries in the population. When…”
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Effects of Fumonisin B 1 in Pregnant Rats. Part 2 by Collins, T.F.X., Sprando, R.L., Black, T.N., Shackelford, M.E., Laborde, J.B., Hansen, D.K., Eppley, R.M., Trucksess, M.W., Howard, P.C., Bryant, M.A., Ruggles, D.I., Olejnik, N., Rorie, J.I.

“…The developmental toxicity of purified fumonisin B 1 (FB1), a mycotoxin from the common corn fungus Fusarium moniliforme, was examined in Charles River rats…”
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Effects of Fumonisin B 1 in Pregnant Rats by Collins, T.F.X., Shackelford, M.E., Sprando, R.L., Black, T.N., Láborde, J.B., Hansen, D.K., Eppley, R.M., Trucksess, M.W., Howard, P.C., Bryant, M.A., Ruggles, D.I., Olejnik, N., Rorie, J.I.

“…Fumonisin B 1 (FB1), the major mycotoxin from Fusarium moniliforme, has been implicated as a causative agent in several animal and human diseases. Despite…”
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Effects of fumonisin B1 in pregnant rats by COLLINS, T. F. X, SHACKELFORD, M. E, RUGGLES, D. I, OLEJNIK, N, RORIE, J. I, SPRANDO, R. L, BLACK, T. N, LABORDE, J. B, HANSEN, D. K, EPPLEY, R. M, TRUCKSESS, M. W, HOWARD, P. C, BRYANT, M. A

“…Fumonisin B1 (FB1), the major mycotoxin from Fusarium moniliforme, has been implicated as a causative agent in several animal and human diseases. Despite…”
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Teratogenic potential of FD&C Red No. 3 when given by gavage by Collins, T F, Black, T N, Ruggles, D I

“…FD&C Red No. 3 (erythrosine) is a commonly used food additive. As part of a series of studies on the potential fetal developmental effects of food colors, FD&C…”
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Developmental toxicity of Orange B given to rats in drinking water by Collins, T F, Black, T N, Ruggles, D I

“…Orange B, a pyrazolone dye used to color frankfurter and sausage casings, was given in distilled drinking water to pregnant Osborne-Mendel rats throughout…”
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Developmental toxicity of orange B when given to rats by gavage by Collins, T F, Black, T N, Rorie, J I, Sprando, R L, Ruggles, D I

“…The pyrazolone dye Orange B was given by gavage to pregnant Osborne-Mendel rats throughout gestation. Dose levels of 0, 15, 30, 100, 200, 400, or 700 mg/kg…”
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Intermediate-duration toxicity study of patulin in rats by Dailey, R E, Brouwer, E, Blaschka, A M, Reynaldo, E F, Green, S, Monlux, W S, Ruggles, D I

“…The toxicity of patulin was studied in two generations of Sprague-Dawley rats over a period of approximately 10 months. Patulin in 1 mM citrate buffer was…”
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Teratological evaluation of FD&C Red no. 2-a collaborative government -industry study. V. Combined findings and discussion by Holson, Jr, J F, Gaylor, D W, Schumacher, H J, Collins, T F, Ruggles, D I, Keplinger, M L, Kennedy, Jr, G L

“…Because of recent studies indicating possible embryolethality and teratogenicity of FD&C Red No. 2, anad hoc committee was convened by the Food and Drug…”
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