Search Results - "Ruggeri, Jeanine M"

Discoidin Domain Receptor 1 (DDR1) Is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma by Ruggeri, Jeanine M., Franco-Barraza, Janusz, Sohail, Anjum, Zhang, Yaqing, Long, Daniel, Pasca di Magliano, Marina, Cukierman, Edna, Fridman, Rafael, Crawford, Howard C.

“…Pancreatic ductal adenocarcinoma (PDA) and chronic pancreatitis are characterized by a dense collagen-rich desmoplastic reaction. Discoidin domain receptor 1…”
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PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance by Roy, Nilotpal, Takeuchi, Kenneth K, Ruggeri, Jeanine M, Bailey, Peter, Chang, David, Li, Joey, Leonhardt, Laura, Puri, Sapna, Hoffman, Megan T, Gao, Shan, Halbrook, Christopher J, Song, Yan, Ljungman, Mats, Malik, Shivani, Wright, Christopher V E, Dawson, David W, Biankin, Andrew V, Hebrok, Matthias, Crawford, Howard C

“…Aberrant activation of embryonic signaling pathways is frequent in pancreatic ductal adenocarcinoma (PDA), making developmental regulators therapeutically…”
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Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis by Halbrook, Christopher J, Wen, Hui-Ju, Ruggeri, Jeanine M, Takeuchi, Kenneth K, Zhang, Yaqing, Pasca di Magliano, Marina, Crawford, Howard C

“…Background & Aims Mitogen-activated protein kinase (MAPK) signaling in the exocrine pancreas has been extensively studied in the context of pancreatic cancer,…”
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BRCA1 R71K missense mutation contributes to cancer predisposition by increasing alternative transcript levels by Zhang, Liying, Chen, Lishi, Bacares, Ruben, Ruggeri, Jeanine M., Somar, Joshua, Kemel, Yelena, Stadler, Zsofia K., Offit, Kenneth

“…Mutation screening of the breast and ovarian cancer predisposition genes BRCA1 and BRCA2 is becoming an increasingly important part of clinical practice…”
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Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in PancreatitisSummary by Christopher J. Halbrook, Hui-Ju Wen, Jeanine M. Ruggeri, Kenneth K. Takeuchi, Yaqing Zhang, Marina Pasca di Magliano, Howard C. Crawford

“…Background & Aims: Mitogen-activated protein kinase (MAPK) signaling in the exocrine pancreas has been extensively studied in the context of pancreatic cancer,…”
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