Search Results - "Ruggeri, Chiara"

Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors by Mistry, Shailesh N, Drinkwater, Nyssa, Ruggeri, Chiara, Sivaraman, Komagal Kannan, Loganathan, Sasdekumar, Fletcher, Sabine, Drag, Marcin, Paiardini, Alessandro, Avery, Vicky M, Scammells, Peter J, McGowan, Sheena

“…Plasmodium parasites, the causative agents of malaria, have developed resistance to most of our current antimalarial therapies, including artemisinin…”
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Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening by Ruggeri, Chiara, Drinkwater, Nyssa, Sivaraman, Komagal Kannan, Bamert, Rebecca S, McGowan, Sheena, Paiardini, Alessandro

“…The Plasmodium falciparum PfA-M1 and PfA-M17 metalloaminopeptidases are validated drug targets for the discovery of antimalarial agents. In order to identify…”
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Ribosome biogenesis factors—from names to functions by Dörner, Kerstin, Ruggeri, Chiara, Zemp, Ivo, Kutay, Ulrike

“…The assembly of ribosomal subunits is a highly orchestrated process that involves a huge cohort of accessory factors. Most eukaryotic ribosome biogenesis…”
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Autophagy Involvement in Non-Neoplastic and Neoplastic Endometrial Pathology: The State of the Art with a Focus on Carcinoma by Pizzimenti, Cristina, Fiorentino, Vincenzo, Ruggeri, Chiara, Franchina, Mariausilia, Ercoli, Alfredo, Tuccari, Giovanni, Ieni, Antonio

“…Autophagy is a cellular process crucial for maintaining homeostasis by degrading damaged proteins and organelles. It is stimulated in response to stress,…”
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Synthesis and Structure–Activity Relationships of Phosphonic Arginine Mimetics as Inhibitors of the M1 and M17 Aminopeptidases from Plasmodium falciparum by Kannan Sivaraman, Komagal, Paiardini, Alessandro, Sieńczyk, Marcin, Ruggeri, Chiara, Oellig, Christine A, Dalton, John P, Scammells, Peter J, Drag, Marcin, McGowan, Sheena

“…The malaria parasite Plasmodium falciparum employs two metallo-aminopeptidases, PfA-M1 and PfA-M17, which are essential for parasite survival. Compounds that…”
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Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions by Drinkwater, Nyssa, Vinh, Natalie B., Mistry, Shailesh N., Bamert, Rebecca S., Ruggeri, Chiara, Holleran, John P., Loganathan, Sasdekumar, Paiardini, Alessandro, Charman, Susan A., Powell, Andrew K., Avery, Vicky M., McGowan, Sheena, Scammells, Peter J.

“…Malaria remains a global health problem, and though international efforts for treatment and eradication have made some headway, the emergence of drug-resistant…”
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Implantable cardioverter-defibrillator deactivation at the end of life: ethical, clinical and communication issues by Romanò, Massimo, Piga, Maria Antonella, Bertona, Roberta, Negro, Roberto, Ruggeri, Chiara, Zorzoli, Federica, Villani, Rosvaldo

“…The number of cardioverter-defibrillator implants is increasing worldwide, with the main indication being primary prevention of sudden cardiac death. During…”
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Real-time assays for detection of Phytophthora spp. and identification of an avr3a gene variant by Tolba, Shimaa R. T., Sialer, Mariella M. Finetti, Rosso, Laura C., Moustafa, Mahmoud M. A., Ruggeri, Chiara, El-Shawaf, Ibrahim I. S., Ciancio, Aurelio

“…A study was carried out for identification and detection of Phytophthora spp. from soil and plant samples, collected from Solanaceous crops in Egypt and Italy…”
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Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening: e0138957 by Ruggeri, Chiara, Drinkwater, Nyssa, Sivaraman, Komagal Kannan, Bamert, Rebecca S, McGowan, Sheena, Paiardini, Alessandro

“…The Plasmodium falciparum PfA-M1 and PfA-M17 metalloaminopeptidases are validated drug targets for the discovery of antimalarial agents. In order to identify…”
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Transient trifascicular block complicating myocardial contusion after blunt chest trauma: a case report by Bortnik, Miriam, Occhetta, Eraldo, Ruggeri, Chiara, Marino, Paolo

“…Cardiac contusion may be frequently found in patients with blunt chest trauma, and it presents clinically as a spectrum of injuries of varying severity,…”
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