Search Results - "Ruge, Maximilian"

Applications of radiomics and machine learning for radiotherapy of malignant brain tumors by Kocher, Martin, Ruge, Maximilian I., Galldiks, Norbert, Lohmann, Philipp

“…Background Magnetic resonance imaging (MRI) and amino acid positron-emission tomography (PET) of the brain contain a vast amount of structural and functional…”
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Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO resect group by Karschnia, Philipp, Young, Jacob S, Dono, Antonio, Häni, Levin, Sciortino, Tommaso, Bruno, Francesco, Juenger, Stephanie T, Teske, Nico, Morshed, Ramin A, Haddad, Alexander F, Zhang, Yalan, Stoecklein, Sophia, Weller, Michael, Vogelbaum, Michael A, Beck, Juergen, Tandon, Nitin, Hervey-Jumper, Shawn, Molinaro, Annette M, Rudà, Roberta, Bello, Lorenzo, Schnell, Oliver, Esquenazi, Yoshua, Ruge, Maximilian I, Grau, Stefan J, Berger, Mitchel S, Chang, Susan M, van den Bent, Martin, Tonn, Joerg-Christian

“…Abstract Background Terminology to describe extent of resection in glioblastoma is inconsistent across clinical trials. A surgical classification system was…”
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Update on the diagnostic value and safety of stereotactic biopsy for pediatric brainstem tumors: a systematic review and meta-analysis of 735 cases by Hamisch, Christina, Kickingereder, Philipp, Fischer, Matthias, Simon, Thorsten, Ruge, Maximilian I

“…OBJECTIVE Recent studies have shed light on the molecular makeup of diffuse intrinsic pontine gliomas and led to the identification of potential treatment…”
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Robotic Stereotactic Radiosurgery in Melanoma Patients with Brain Metastases under Simultaneous Anti-PD-1 Treatment by Trommer-Nestler, Maike, Marnitz, Simone, Kocher, Martin, Rueß, Daniel, Schlaak, Max, Theurich, Sebastian, von Bergwelt-Baildon, Michael, Morgenthaler, Janis, Jablonska, Karolina, Celik, Eren, Ruge, Maximilian I, Baues, Christian

“…Combination concepts of radiotherapy and immune checkpoint inhibition are currently of high interest. We examined imaging findings, acute toxicity, and local…”
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Diagnostic Value and Safety of Stereotactic Biopsy for Brainstem Tumors: A Systematic Review and Meta-analysis of 1480 Cases by Kickingereder, Philipp, Willeit, Peter, Simon, Thorsten, Ruge, Maximilian I.

“…Abstract BACKGROUND: The feasibility and safety of stereotactic biopsy for brainstem tumors (BSTs) are controversial. Although magnetic resonance imaging (MRI)…”
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Radiomics for the noninvasive prediction of the BRAF mutation status in patients with melanoma brain metastases by Meißner, Anna-Katharina, Gutsche, Robin, Galldiks, Norbert, Kocher, Martin, Jünger, Stephanie T, Eich, Marie-Lisa, Montesinos-Rongen, Manuel, Brunn, Anna, Deckert, Martina, Wendl, Christina, Dietmaier, Wolfgang, Goldbrunner, Roland, Ruge, Maximilian I, Mauch, Cornelia, Schmidt, Nils-Ole, Proescholdt, Martin, Grau, Stefan, Lohmann, Philipp

“…Abstract Background The BRAF V600E mutation is present in approximately 50% of patients with melanoma brain metastases and an important prerequisite for…”
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Radiomics for the non-invasive prediction of PD-L1 expression in patients with brain metastases secondary to non-small cell lung cancer by Meißner, Anna-Katharina, Gutsche, Robin, Galldiks, Norbert, Kocher, Martin, Jünger, Stephanie T., Eich, Marie-Lisa, Nogova, Lucia, Araceli, Tommaso, Schmidt, Nils Ole, Ruge, Maximilian I., Goldbrunner, Roland, Proescholdt, Martin, Grau, Stefan, Lohmann, Philipp

“…Background The expression level of the programmed cell death ligand 1 (PD-L1) appears to be a predictor for response to immunotherapy using checkpoint…”
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Diagnosis of pseudoprogression in patients with glioblastoma using O-(2-[18F]fluoroethyl)-l-tyrosine PET by Galldiks, Norbert, Dunkl, Veronika, Stoffels, Gabriele, Hutterer, Markus, Rapp, Marion, Sabel, Michael, Reifenberger, Guido, Kebir, Sied, Dorn, Franziska, Blau, Tobias, Herrlinger, Ulrich, Hau, Peter, Ruge, Maximilian I., Kocher, Martin, Goldbrunner, Roland, Fink, Gereon R., Drzezga, Alexander, Schmidt, Matthias, Langen, Karl-Josef

“…Purpose The follow-up of glioblastoma patients after radiochemotherapy with conventional MRI can be difficult since reactive alterations to the blood–brain…”
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Connectivity in deep brain stimulation for self-injurious behavior: multiple targets for a common network? by Heiden, Petra, Weigel, Daniel Tim, Loução, Ricardo, Hamisch, Christina, Gündüz, Enes M., Ruge, Maximilian I., Kuhn, Jens, Visser-Vandewalle, Veerle, Andrade, Pablo

“…Self-injurious behavior (SIB) is associated with diverse psychiatric conditions. Sometimes (e.g., in patients with autism spectrum disorder or acquired brain…”
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Streamlined Intraoperative Brain Tumor Classification and Molecular Subtyping in Stereotactic Biopsies Using Stimulated Raman Histology and Deep Learning by Reinecke, David, Ruess, Daniel, Meissner, Anna-Katharina, Fürtjes, Gina, von Spreckelsen, Niklas, Ion-Margineanu, Adrian, Khalid, Florian, Blau, Tobias, Stehle, Thomas, Al-Shugri, Abdulkader, Büttner, Reinhard, Goldbrunner, Roland, Ruge, Maximilian I, Neuschmelting, Volker

“…Recent artificial intelligence algorithms aided intraoperative decision-making via stimulated Raman histology (SRH) during craniotomy. This study assesses deep…”
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Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis by Lohmann, Philipp, Kocher, Martin, Ceccon, Garry, Bauer, Elena K., Stoffels, Gabriele, Viswanathan, Shivakumar, Ruge, Maximilian I., Neumaier, Bernd, Shah, Nadim J., Fink, Gereon R., Langen, Karl-Josef, Galldiks, Norbert

“…The aim of this study was to investigate the potential of combined textural feature analysis of contrast-enhanced MRI (CE-MRI) and static…”
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Dynamic O-(2-18F-fluoroethyl)-L-tyrosine positron emission tomography differentiates brain metastasis recurrence from radiation injury after radiotherapy by Ceccon, Garry, Lohmann, Philipp, Stoffels, Gabriele, Judov, Natalie, Filss, Christian P, Rapp, Marion, Bauer, Elena, Hamisch, Christina, Ruge, Maximilian I, Kocher, Martin, Kuchelmeister, Klaus, Sellhaus, Bernd, Sabel, Michael, Fink, Gereon R, Shah, Nadim J, Langen, Karl-Josef, Galldiks, Norbert

“…The aim of this study was to investigate the potential of dynamic O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET) PET for differentiating local recurrent brain…”
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Multimodal imaging findings in patients with glioblastoma with extensive coagulative necrosis related to regorafenib by Werner, Jan-Michael, Wollring, Michael M, Tscherpel, Caroline, Rosen, Elena K, Werr, Lisa, Stetter, Isabelle, Rueß, Daniel, Ruge, Maximilian I, Brunn, Anna, Al Shughri, Abdulkader, Kabbasch, Christoph, Fink, Gereon R, Langen, Karl-Josef, Galldiks, Norbert

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Role of O -(2- 18 F-Fluoroethyl)-l-Tyrosine PET for Differentiation of Local Recurrent Brain Metastasis from Radiation Necrosis by Galldiks, Norbert, Stoffels, Gabriele, Filss, Christian P., Piroth, Marc D., Sabel, Michael, Ruge, Maximilian I., Herzog, Hans, Shah, Nadim J., Fink, Gereon R., Coenen, Heinz H., Langen, Karl-Josef

“…The aim of this study was to investigate the potential of O-(2-18F-fluoroethyl)-L-tyrosine (18F-FET) PET for differentiating local recurrent brain metastasis…”
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Observation after surgery for low grade glioma: long-term outcome in the light of the 2016 WHO classification by Jansen, Elena, Hamisch, Christina, Ruess, Daniel, Heiland, Dieter Henrik, Goldbrunner, Roland, Ruge, Maximilian I., Schnell, Oliver, Grau, Stefan J.

“…Purpose To provide detailed long-term data after initial observation for patients after histological confirmation of low grade (WHO II) gliomas according to…”
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Deep convolutional neural networks for automated segmentation of brain metastases trained on clinical data by Bousabarah, Khaled, Ruge, Maximilian, Brand, Julia-Sarita, Hoevels, Mauritius, Rueß, Daniel, Borggrefe, Jan, Große Hokamp, Nils, Visser-Vandewalle, Veerle, Maintz, David, Treuer, Harald, Kocher, Martin

“…Deep learning-based algorithms have demonstrated enormous performance in segmentation of medical images. We collected a dataset of multiparametric MRI and…”
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Novel rapid intraoperative qualitative tumor detection by a residual convolutional neural network using label-free stimulated Raman scattering microscopy by Reinecke, David, von Spreckelsen, Niklas, Mawrin, Christian, Ion-Margineanu, Adrian, Fürtjes, Gina, Jünger, Stephanie T, Khalid, Florian, Freudiger, Christian W, Timmer, Marco, Ruge, Maximilian I, Goldbrunner, Roland, Neuschmelting, Volker

“…Determining the presence of tumor in biopsies and the decision-making during resections is often dependent on intraoperative rapid frozen-section…”
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Entirely noninvasive outcome prediction in central nervous system lymphomas using circulating tumor DNA by Heger, Jan-Michel, Mattlener, Julia, Schneider, Jessica, Gödel, Philipp, Sieg, Noëlle, Ullrich, Fabian, Lewis, Richard, Bucaciuc-Mracica, Teodora, Schwarz, Roland F., Rueß, Daniel, Ruge, Maximilian I., Montesinos-Rongen, Manuel, Deckert, Martina, Blau, Tobias, Kutsch, Nadine, Balke-Want, Hyatt, Weiss, Jonathan, Becker, Kerstin, Reinhardt, H. Christian, Hallek, Michael, Borchmann, Peter, von Tresckow, Bastian, Borchmann, Sven

“…•Tumor-agnostic ctDNA sequencing in CNSL is feasible and allows for detection of PRD.•We propose the molecular prognostic index for CNSL, a model integrating…”
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Analysis of Driver Mutational Hot Spots in Blood-Derived Cell-Free DNA of Patients with Primary Central Nervous System Lymphoma Obtained before Intracerebral Biopsy by Montesinos-Rongen, Manuel, Brunn, Anna, Tuchscherer, Armin, Borchmann, Peter, Schorb, Elisabeth, Kasenda, Benjamin, Altmüller, Janine, Illerhaus, Gerald, Ruge, Maximilian I., Maarouf, Mohammad, Büttner, Reinhard, Hansmann, Martin-Leo, Hallek, Michael, Prinz, Marco, Siebert, Reiner, Deckert, Martina

“…In newly diagnosed systemic diffuse large B-cell lymphoma, next-generation sequencing of plasma-derived cell-free DNA (cfDNA) detects somatic mutations as…”
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Stereotactic radiosurgery and radiotherapy for brainstem metastases: An international multicenter analysis by Ehret, Felix, Rueß, Daniel, Blanck, Oliver, Fichte, Susanne, Chatzikonstantinou, Georgios, Wolff, Robert, Mose, Lucas, Mose, Stephan, Fortmann, Thomas, Lehrke, Ralph, Turna, Menekse, Caglar, Hale Basak, Mortasawi, Farshin, Bleif, Martin, Krug, David, Ruge, Maximilian I., Fürweger, Christoph, Muacevic, Alexander

“…Brainstem metastases (BSM) present a significant neuro‐oncological challenge, resulting in profound neurological deficits and poor survival outcomes…”
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