Search Results - "Rug, Melanie"
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Cell-Cell Communication between Malaria-Infected Red Blood Cells via Exosome-like Vesicles
Published in Cell (23-05-2013)“…Cell-cell communication is an important mechanism for information exchange promoting cell survival for the control of features such as population density and…”
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A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts
Published in PLoS pathogens (20-09-2022)“…Protein export and host membrane remodeling are crucial for multiple Plasmodium species to establish a niche in infected hosts. To better understand the…”
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Targeting Malaria Virulence and Remodeling Proteins to the Host Erythrocyte
Published in Science (American Association for the Advancement of Science) (10-12-2004)“…To establish infection in the host, malaria parasites export remodeling and virulence proteins into the erythrocyte. These proteins can traverse a series of…”
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Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes
Published in Cell (11-07-2008)“…A major part of virulence for Plasmodium falciparum malaria infection, the most lethal parasitic disease of humans, results from increased rigidity and…”
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Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum
Published in Malaria journal (06-02-2016)“…The development of differentiated sexual stages (gametocytes) within human red blood cells is essential for the propagation of the malaria parasite, since only…”
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Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton
Published in Blood (27-11-2014)“…Following invasion of human red blood cells (RBCs) by the malaria parasite, Plasmodium falciparum, a remarkable process of remodeling occurs in the host cell…”
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Automated Fourier space region-recognition filtering for off-axis digital holographic microscopy
Published in Biomedical optics express (01-08-2016)“…Automated label-free quantitative imaging of biological samples can greatly benefit high throughput diseases diagnosis. Digital holographic microscopy (DHM) is…”
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A Conserved Molecular Motor Drives Cell Invasion and Gliding Motility across Malaria Life Cycle Stages and Other Apicomplexan Parasites
Published in The Journal of biological chemistry (24-02-2006)“…Apicomplexan parasites constitute one of the most significant groups of pathogens infecting humans and animals. The liver stage sporozoites of Plasmodium spp…”
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Characterisation of Hybrid Polymersome Vesicles Containing the Efflux Pumps NaAtm1 or P-Glycoprotein
Published in Polymers (03-05-2020)“…Investigative systems for purified membrane transporters are almost exclusively reliant on the use of phospholipid vesicles or liposomes. Liposomes provide an…”
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A Synergistic Genetic Engineering Strategy Induced Triacylglycerol Accumulation in Potato ( Solanum tuberosum ) Leaf
Published in Frontiers in plant science (06-03-2020)“…Potato is the 4th largest staple food in the world currently. As a high biomass crop, potato harbors excellent potential to produce energy-rich compounds such…”
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The role of KAHRP domains in knob formation and cytoadherence of P falciparum-infected human erythrocytes
Published in Blood (01-07-2006)“…Surface protrusions of Plasmodium falciparum-infected erythrocytes, called knobs, display focal aggregates of P falciparum erythrocyte membrane protein 1…”
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Skeleton-binding protein 1 functions at the parasitophorous vacuole membrane to traffic PfEMP1 to the Plasmodium falciparum–infected erythrocyte surface
Published in Blood (01-02-2007)“…A key feature of Plasmodium falciparum, the parasite causing the most severe form of malaria in humans, is its ability to export parasite molecules onto the…”
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Wherever I may roam: Protein and membrane trafficking in P. falciparum-infected red blood cells
Published in Molecular and biochemical parasitology (01-12-2012)“…P. falciparum is an interesting eukaryotic model system to study protein trafficking. The P. falciparum-infected erythrocyte contains numerous uncommon…”
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Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of Plasmodium falciparum-infected erythrocytes
Published in Molecular microbiology (01-06-2008)“…During the intra-erythrocytic development of Plasmodium falciparum, the parasite modifies the host cell surface by exporting proteins that interact with or…”
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Signal-mediated export of proteins from the malaria parasite to the host erythrocyte
Published in The Journal of cell biology (21-11-2005)“…Intracellular parasites from the genus Plasmodium reside and multiply in a variety of cells during their development. After invasion of human erythrocytes,…”
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Trafficking of the major virulence factor to the surface of transfected P falciparum–infected erythrocytes
Published in Blood (15-05-2005)“…After invading human red blood cells (RBCs) the malaria parasite Plasmodium falciparum remodels the host cell by trafficking proteins to the RBC compartment…”
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Genesis of and Trafficking to the Maurer's Clefts of Plasmodium falciparum-Infected Erythrocytes
Published in Molecular and Cellular Biology (01-06-2006)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Shigella flexneri infection in Caenorhabditis elegans: cytopathological examination and identification of host responses
Published in PloS one (04-09-2014)“…The Gram-negative bacterium Shigella flexneri is the causative agent of shigellosis, a diarrhoeal disease also known as bacillary dysentery. S. flexneri…”
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The Signal Sequence of Exported Protein-1 Directs the Green Fluorescent Protein to the Parasitophorous Vacuole of Transfected Malaria Parasites
Published in The Journal of biological chemistry (21-02-2003)“…The malaria parasite, Plasmodium falciparum , spends part of its life cycle inside the erythrocytes of its human host. In the mature stages of…”
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Trafficking determinants for PfEMP3 export and assembly under the Plasmodium falciparum‐infected red blood cell membrane
Published in Molecular microbiology (01-11-2005)“…Summary During the maturation of intracellular asexual stages of Plasmodium falciparum parasite‐encoded proteins are exported into the erythrocyte cytosol. A…”
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