Search Results - "Rug, Melanie"

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  1. 1

    Cell-Cell Communication between Malaria-Infected Red Blood Cells via Exosome-like Vesicles by Regev-Rudzki, Neta, Wilson, Danny W., Carvalho, Teresa G., Sisquella, Xavier, Coleman, Bradley M., Rug, Melanie, Bursac, Dejan, Angrisano, Fiona, Gee, Michelle, Hill, Andrew F., Baum, Jake, Cowman, Alan F.

    Published in Cell (23-05-2013)
    “…Cell-cell communication is an important mechanism for information exchange promoting cell survival for the control of features such as population density and…”
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  2. 2

    A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts by Gabelich, Julie-Anne, Grützke, Josephine, Kirscht, Florian, Popp, Oliver, Matz, Joachim M, Dittmar, Gunnar, Rug, Melanie, Ingmundson, Alyssa

    Published in PLoS pathogens (20-09-2022)
    “…Protein export and host membrane remodeling are crucial for multiple Plasmodium species to establish a niche in infected hosts. To better understand the…”
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  3. 3

    Targeting Malaria Virulence and Remodeling Proteins to the Host Erythrocyte by Marti, Matthias, Good, Robert T., Rug, Melanie, Knuepfer, Ellen, Cowman, Alan F.

    “…To establish infection in the host, malaria parasites export remodeling and virulence proteins into the erythrocyte. These proteins can traverse a series of…”
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  4. 4

    Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes by Maier, Alexander G., Rug, Melanie, O'Neill, Matthew T., Brown, Monica, Chakravorty, Srabasti, Szestak, Tadge, Chesson, Joanne, Wu, Yang, Hughes, Katie, Coppel, Ross L., Newbold, Chris, Beeson, James G., Craig, Alister, Crabb, Brendan S., Cowman, Alan F.

    Published in Cell (11-07-2008)
    “…A major part of virulence for Plasmodium falciparum malaria infection, the most lethal parasitic disease of humans, results from increased rigidity and…”
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  5. 5

    Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum by Tran, Phuong N, Brown, Simon H J, Rug, Melanie, Ridgway, Melanie C, Mitchell, Todd W, Maier, Alexander G

    Published in Malaria journal (06-02-2016)
    “…The development of differentiated sexual stages (gametocytes) within human red blood cells is essential for the propagation of the malaria parasite, since only…”
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  6. 6

    Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton by Rug, Melanie, Cyrklaff, Marek, Mikkonen, Antti, Lemgruber, Leandro, Kuelzer, Simone, Sanchez, Cecilia P., Thompson, Jennifer, Hanssen, Eric, O’Neill, Matthew, Langer, Christine, Lanzer, Michael, Frischknecht, Friedrich, Maier, Alexander G., Cowman, Alan F.

    Published in Blood (27-11-2014)
    “…Following invasion of human red blood cells (RBCs) by the malaria parasite, Plasmodium falciparum, a remarkable process of remodeling occurs in the host cell…”
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  7. 7

    Automated Fourier space region-recognition filtering for off-axis digital holographic microscopy by He, Xuefei, Nguyen, Chuong Vinh, Pratap, Mrinalini, Zheng, Yujie, Wang, Yi, Nisbet, David R, Williams, Richard J, Rug, Melanie, Maier, Alexander G, Lee, Woei Ming

    Published in Biomedical optics express (01-08-2016)
    “…Automated label-free quantitative imaging of biological samples can greatly benefit high throughput diseases diagnosis. Digital holographic microscopy (DHM) is…”
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  8. 8

    A Conserved Molecular Motor Drives Cell Invasion and Gliding Motility across Malaria Life Cycle Stages and Other Apicomplexan Parasites by Baum, Jake, Richard, Dave, Healer, Julie, Rug, Melanie, Krnajski, Zita, Gilberger, Tim-Wolf, Green, Judith L., Holder, Anthony A., Cowman, Alan F.

    Published in The Journal of biological chemistry (24-02-2006)
    “…Apicomplexan parasites constitute one of the most significant groups of pathogens infecting humans and animals. The liver stage sporozoites of Plasmodium spp…”
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  9. 9

    Characterisation of Hybrid Polymersome Vesicles Containing the Efflux Pumps NaAtm1 or P-Glycoprotein by Rottet, Sarah, Iqbal, Shagufta, Beales, Paul A, Lin, Anran, Lee, Jiwon, Rug, Melanie, Scott, Colin, Callaghan, Richard

    Published in Polymers (03-05-2020)
    “…Investigative systems for purified membrane transporters are almost exclusively reliant on the use of phospholipid vesicles or liposomes. Liposomes provide an…”
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  10. 10

    A Synergistic Genetic Engineering Strategy Induced Triacylglycerol Accumulation in Potato ( Solanum tuberosum ) Leaf by Xu, Xiao-Yu, Akbar, Sehrish, Shrestha, Pushkar, Venugoban, Lauren, Devilla, Rosangela, Hussain, Dawar, Lee, Jiwon, Rug, Melanie, Tian, Lijun, Vanhercke, Thomas, Singh, Surinder P, Li, Zhongyi, Sharp, Peter J, Liu, Qing

    Published in Frontiers in plant science (06-03-2020)
    “…Potato is the 4th largest staple food in the world currently. As a high biomass crop, potato harbors excellent potential to produce energy-rich compounds such…”
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  11. 11

    The role of KAHRP domains in knob formation and cytoadherence of P falciparum-infected human erythrocytes by Rug, Melanie, Prescott, Stuart W., Fernandez, Kate M., Cooke, Brian M., Cowman, Alan F.

    Published in Blood (01-07-2006)
    “…Surface protrusions of Plasmodium falciparum-infected erythrocytes, called knobs, display focal aggregates of P falciparum erythrocyte membrane protein 1…”
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  12. 12

    Skeleton-binding protein 1 functions at the parasitophorous vacuole membrane to traffic PfEMP1 to the Plasmodium falciparum–infected erythrocyte surface by Maier, Alexander G., Rug, Melanie, O'Neill, Matthew T., Beeson, James G., Marti, Matthias, Reeder, John, Cowman, Alan F.

    Published in Blood (01-02-2007)
    “…A key feature of Plasmodium falciparum, the parasite causing the most severe form of malaria in humans, is its ability to export parasite molecules onto the…”
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  13. 13

    Wherever I may roam: Protein and membrane trafficking in P. falciparum-infected red blood cells by Deponte, Marcel, Hoppe, Heinrich C., Lee, Marcus C.S., Maier, Alexander G., Richard, Dave, Rug, Melanie, Spielmann, Tobias, Przyborski, Jude M.

    Published in Molecular and biochemical parasitology (01-12-2012)
    “…P. falciparum is an interesting eukaryotic model system to study protein trafficking. The P. falciparum-infected erythrocyte contains numerous uncommon…”
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  14. 14

    Maurer's cleft protein MAHRP1 is essential for trafficking of PfEMP1 to the surface of Plasmodium falciparum-infected erythrocytes by Spycher, Cornelia, Rug, Melanie, Pachlatko, Esther, Hanssen, Eric, Ferguson, David, Cowman, Alan F, Tilley, Leann, Beck, Hans-Peter

    Published in Molecular microbiology (01-06-2008)
    “…During the intra-erythrocytic development of Plasmodium falciparum, the parasite modifies the host cell surface by exporting proteins that interact with or…”
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  15. 15

    Signal-mediated export of proteins from the malaria parasite to the host erythrocyte by Marti, Matthias, Baum, Jake, Rug, Melanie, Tilley, Leann, Cowman, Alan F

    Published in The Journal of cell biology (21-11-2005)
    “…Intracellular parasites from the genus Plasmodium reside and multiply in a variety of cells during their development. After invasion of human erythrocytes,…”
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  16. 16

    Trafficking of the major virulence factor to the surface of transfected P falciparum–infected erythrocytes by Knuepfer, Ellen, Rug, Melanie, Klonis, Nectarios, Tilley, Leann, Cowman, Alan F.

    Published in Blood (15-05-2005)
    “…After invading human red blood cells (RBCs) the malaria parasite Plasmodium falciparum remodels the host cell by trafficking proteins to the RBC compartment…”
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  17. 17

    Genesis of and Trafficking to the Maurer's Clefts of Plasmodium falciparum-Infected Erythrocytes by Spycher, Cornelia, Rug, Melanie, Klonis, Nectarios, Ferguson, David J. P., Cowman, Alan F., Beck, Hans-Peter, Tilley, Leann

    Published in Molecular and Cellular Biology (01-06-2006)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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  18. 18

    Shigella flexneri infection in Caenorhabditis elegans: cytopathological examination and identification of host responses by George, Divya T, Behm, Carolyn A, Hall, David H, Mathesius, Ulrike, Rug, Melanie, Nguyen, Ken C Q, Verma, Naresh K

    Published in PloS one (04-09-2014)
    “…The Gram-negative bacterium Shigella flexneri is the causative agent of shigellosis, a diarrhoeal disease also known as bacillary dysentery. S. flexneri…”
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  19. 19

    The Signal Sequence of Exported Protein-1 Directs the Green Fluorescent Protein to the Parasitophorous Vacuole of Transfected Malaria Parasites by Adisa, Akinola, Rug, Melanie, Klonis, Nectarios, Foley, Michael, Cowman, Alan F, Tilley, Leann

    Published in The Journal of biological chemistry (21-02-2003)
    “…The malaria parasite, Plasmodium falciparum , spends part of its life cycle inside the erythrocytes of its human host. In the mature stages of…”
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  20. 20

    Trafficking determinants for PfEMP3 export and assembly under the Plasmodium falciparum‐infected red blood cell membrane by Knuepfer, Ellen, Rug, Melanie, Klonis, Nectarios, Tilley, Leann, Cowman, Alan F.

    Published in Molecular microbiology (01-11-2005)
    “…Summary During the maturation of intracellular asexual stages of Plasmodium falciparum parasite‐encoded proteins are exported into the erythrocyte cytosol. A…”
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