Search Results - "Rufino, Ana Teresa"
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Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis
Published in European journal of pharmacology (05-03-2015)“…Osteoarthritis is a progressive joint disease and a major cause of disability for which no curative therapies are yet available. To identify compounds with…”
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2-Styrylchromones Prevent IL-1β-Induced Pro-Inflammatory Activation of Fibroblast-like Synoviocytes while Increasing COX-2 Expression
Published in Pharmaceutics (26-02-2023)“…Rheumatoid arthritis (RA) is characterized by systemic immune and chronic inflammatory features, leading to the destruction of the joints. Presently, there are…”
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Gossypetin Is a Novel Modulator of Inflammatory Cytokine Production and a Suppressor of Osteosarcoma Cell Growth
Published in Antioxidants (01-09-2023)“…Osteosarcoma (OS) is a common childhood sarcoma, and its treatment is hindered by adverse effects, chemoresistance, and recurrence. Interleukin (IL)-6…”
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2-Styrylchromones Inhibit IL-1β-Induced Inflammatory Mediators’ Production in Human Fibroblast-like Synoviocytes
Published in Medical sciences forum (01-11-2022)“…Rheumatoid arthritis (RA) is a progressive and chronic autoimmune disease that is characterized by persistent synovial inflammation and irreversible cartilage…”
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Chalcones as Potential Inhibitors of Pancreatic Lipase
Published in Medical sciences forum (01-11-2022)“…Obesity is a global disease that has been escalating to epidemic proportions over the past years. A recent report from World Obesity Federation predicts that,…”
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Assessment of cell line competence for studies of pharmacological GPR30 modulation
Published in Journal of receptors and signal transduction (04-03-2017)“…Context/objective: Cell lines used to study the role of the G protein-coupled receptor 30 (GPR30) or G protein-coupled estrogen receptor (GPER) as a mediator…”
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Glucose Sensing and Modulation of Human Chondrocyte Functions by Hyperglycemia: Relevance as Pharmacological Targets for Diabetes – Associated OA
Published 01-01-2014“…Osteoarthritis (OA) and Diabetes Mellitus (DM), especially type 2, are age-related diseases with increasing prevalence. Several epidemiological and…”
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Dissertation -
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Tissue Engineered Cartilage in Unconfined Compression: Biomechanical Analysis
Published in Materials today : proceedings (2015)“…In this work we analyzed the mechanical properties of agarose and related the changes in those properties occurring in agarose-chondrocyte constructs cultured…”
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Journal Article