Search Results - "Ruey J Sung"

Myocardial ischemia and ventricular fibrillation: Pathophysiology and clinical implications by Luqman, Nazar, Sung, Ruey J, Wang, Chun-Li, Kuo, Chi-Tai

“…Abstract Ventricular fibrillation (VF) and myocardial ischemia are inseparable. The first clinical manifestation of myocardial ischemia or infarction may be…”
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Targeting intracellular calcium cycling in catecholaminergic polymorphic ventricular tachycardia: a theoretical investigation by Sung, Ruey J, Lo, Chu-Pin, Hsiao, Pi Yin, Tien, Hui-Chun

“…Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a malignant arrhythmogenic disorder linked to mutations in the cardiac ryanodine receptor…”
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Electrophysiological mechanisms of ventricular arrhythmias in relation to Andersen-Tawil syndrome under conditions of reduced IK1: a simulation study by Sung, Ruey J, Wu, Sheng-Nan, Wu, Jiun-Shian, Chang, Han-Dong, Luo, Ching-Hsing

“…Patients with Andersen-Tawil syndrome (ATS) mostly have mutations on the KCNJ2 gene, producing loss of function or dominant-negative suppression of the inward…”
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Spatial heterogeneity of calcium transient alternans during the early phase of myocardial ischemia in the blood-perfused rabbit heart by QIAN, You-Wen, CLUSIN, William T, LIN, Shien-Fong, HAN, Jennifer, SUNG, Ruey J

“…Optical mapping of cytosolic calcium transients in intact mammalian hearts is now possible using long-wavelength [Ca(2+)](i) indicators. We propose that…”
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Emerging Role of Cardiac Resynchronization Therapy in Heart Failure by Luqman, Nazar, Wang, Chun-li, Sung, Ruey J, Kuo, Chi-tai

“…Morbidity and mortality due to heart failure remains high in spite of advances in its medical management. During the last decade a new modality has emerged…”
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Unusual Features of an Idiopathic Ventricular Tachycardia Arising from the Left Ventricular Outflow Tract by HSU, JEN-TE, LIN, KUO-HUNG, LUQMAN, NAZAR, SUNG, RUEY J., KUO, CHI-TAI

“…We encountered a 40‐year‐old man with recurrent symptomatic palpitations manifested as monomorphic ventricular tachycardia (VT) of a right bundle branch block…”
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Time-Dependent Block of Ultrarapid-Delayed Rectifier K+ Currents by Aconitine, a Potent Cardiotoxin, in Heart-Derived H9c2 Myoblasts and in Neonatal Rat Ventricular Myocytes by Wang, Ya-Jean, Chen, Bing-Shuo, Lin, Ming-Wei, Lin, An-An, Peng, Hsung, Sung, Ruey J., Wu, Sheng-Nan

“…Aconitine (ACO), a highly toxic diterpenoid alkaloid, is recognized to have effects on cardiac voltage-gated Na+ channels. However, it remains unknown whether…”
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Gene mutations in cardiac arrhythmias: a review of recent evidence in ion channelopathies by Hsiao, Pi-Yin, Tien, Hui-Chun, Lo, Chu-Pin, Juang, Jyh-Ming Jimmy, Wang, Yi-Hsin, Sung, Ruey J

“…Over the past 15 years, molecular genetic studies have linked gene mutations to many inherited arrhythmogenic disorders, in particular, "ion channelopathies",…”
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Beta-adrenergic modulation of arrhythmogenesis and identification of targeted sites of antiarrhythmic therapy in Timothy (LQT8) syndrome: a theoretical study by Sung, Ruey J, Wu, Yung-Han, Lai, Nathan Hsing-Jung, Teng, Chun-Hao, Luo, Ching-Hsing, Tien, Hui-Chun, Lo, Chu-Pin, Wu, Sheng-Nan

“…Timothy syndrome (TS) is a malignant form of congenital long QT syndrome with a mode of arrhythmia onset often triggered by enhanced sympathetic tone. We…”
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Identification of two types of ATP-sensitive K + channels in rat ventricular myocytes by Wu, Sheng-Nan, Wu, Adonis Z., Sung, Ruey J.

“…The ATP-sensitive K + (K ATP) channels are known to provide a functional linkage between the electrical activity of the cell membrane and metabolism. Two types…”
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Contribution of BKCa-Channel Activity in Human Cardiac Fibroblasts to Electrical Coupling of Cardiomyocytes-Fibroblasts by Wang, Ya-Jean, Sung, Ruey J, Lin, Ming-Wei, Wu, Sheng-Nan

“…Cardiac fibroblasts are involved in the maintenance of myocardial tissue structure. However, little is known about ion currents in human cardiac fibroblasts…”
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The activation by estrogen receptor agonists of the BKCa-channel in human cardiac fibroblasts by Wang, Ya-Jean, Lin, Ming-Wei, Wu, Sheng-Nan, Sung, Ruey J.

“…The agonists selective for estrogen receptor (ER)-α (4,4′,4′′-(4-propyl-[1H]-pyrazole-1,3,5-triyl) tris-phenol, PPT) and ER-β…”
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Is Electrode Catheter Ablation-Induced Phrenic Nerve Injury Really a Benign Condition? by SUNG, RUEY J., LAUER, MICHAEL R.

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Demonstration of a Posterior Atrial Input to the Atrioventricular Node During Sustained Anterograde Slow Pathway Conduction by Young, Charlie, Lauer, Michael R, Liem, L.Bing, Chun, Hingson, Sung, Ruey J

“…Objectives. This study sought to demonstrate electrophysiologic evidence for the existence of different anatomic atrial input sites of fast and slow conduction…”
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Cocaine‐Induced Inhibition of ATP‐Sensitive K+ Channels in Rat Ventricular Myocytes and in Heart‐Derived H9c2 Cells by Wu, Sheng‐Nan, Chang, Hang‐Dong, Sung, Ruey J.

“…: Cocaine use may cause coronary artery spasm and acute myocardial ischaemia/infarction. However, its effects on ATP‐sensitive K+ (KATP) channel, an ion…”
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Atrial Fibrillation: Can We Cure It If We Can't Explain It? by SUNG, RUEY J., LAUER, MICHAEL R.

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Electrophysiologic mechanisms of the long QT interval syndromes and torsade de pointes by TAN, H. L, HOU, C. J. Y, LAUER, M. R, SUNG, R. J

“…To review the current understanding of the mechanisms and treatment of the long QT interval syndromes and torsade de pointes. Personal databases of the authors…”
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Comparison of a novel rectilinear biphasic waveform with a damped sine wave monophasic waveform for transthoracic ventricular defibrillation by Mittal, Suneet, Ayati, Shervin, Stein, Kenneth M., Knight, Bradley P., Morady, Fred, Schwartzman, David, Cavlovich, Doris, Platia, Edward V., Calkins, Hugh, Tchou, Patrick J., Miller, John M., Wharton, J.Marcus, Sung, Ruey J., Slotwiner, David J., Markowitz, Steven M., Lerman, Bruce B.

“…OBJECTIVES We compared the efficacy of a novel rectilinear biphasic waveform, consisting of a constant current first phase, with a damped sine wave monophasic…”
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Spatial heterogeneity of action potential alternans during global ischemia in the rabbit heart by Qian, You-Wen, Sung, Ruey J, Lin, Shien-Fong, Province, Rose, Clusin, William T

“…Cardiac ischemia causes beat-to-beat fluctuation in action potential duration (APD) alternans, which leads to T wave alternans and arrhythmias. Occurrence of…”
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Intravenous diltiazem for termination of reentrant supraventricular tachycardia: a placebo-controlled, randomized, double-blind, multicenter study by Huycke, Edward C, Sung, Ruey J, Dias, Virgil C, Milstein, Simon, Hariman, Robert J, Platia, Edward V

“…To assess the efficacy and safety of intravenous diltiazem, 54 patients with inducible sustained supraventricular tachycardia received diltiazem, 0.25 mg/kg or…”
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