Search Results - "Ruediger, H."

8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures by Pilger, A, Rüdiger, H W

“…Oxidative DNA damage is considered to play an important role in pathophysiological processes, ageing and cancer. So far major interest has been on measuring…”
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With age spontaneous baroreflex sensitivity diminishes after acute fat ingestion by Wright, C.I., Ruediger, H., Draijer, R.

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Hepatitis C Virus NS5A Replication Complex Inhibitors: The Discovery of Daclatasvir by Belema, Makonen, Nguyen, Van N., Bachand, Carol, Deon, Dan H., Goodrich, Jason T., James, Clint A., Lavoie, Rico, Lopez, Omar D., Martel, Alain, Romine, Jeffrey L., Ruediger, Edward H., Snyder, Lawrence B., Laurent, Denis R. St, Yang, Fukang, Zhu, Juliang, Wong, Henry S., Langley, David R., Adams, Stephen P., Cantor, Glenn H., Chimalakonda, Anjaneya, Fura, Aberra, Johnson, Benjamin M., Knipe, Jay O., Parker, Dawn D., Santone, Kenneth S., Fridell, Robert A., Lemm, Julie A., O’Boyle, Donald R., Colonno, Richard J., Gao, Min, Meanwell, Nicholas A., Hamann, Lawrence G.

“…The biphenyl derivatives 2 and 3 are prototypes of a novel class of NS5A replication complex inhibitors that demonstrate high inhibitory potency toward a panel…”
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Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues by Toulouse, Jacynthe L, Yachnin, Brahm J, Ruediger, Edward H, Deon, Daniel, Gagnon, Marc, Saint-Jacques, Kévin, Ebert, Maximilian C. C. J. C, Forge, Delphine, Bastien, Dominic, Colin, Damien Y, Vanden Eynde, Jean Jacques, Marinier, Anne, Berghuis, Albert M, Pelletier, Joelle N

“…The worldwide use of the broad-spectrum antimicrobial trimethoprim (TMP) has induced the rise of TMP-resistant microorganisms. In addition to…”
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Baroreflex sensitivity and power spectral analysis in different extrapyramidal syndromes by Friedrich, C., Rüdiger, H., Schmidt, C., Herting, B., Prieur, S., Junghanns, S., Schweitzer, K., Globas, C., Schöls, L., Berg, D., Reichmann, H., Ziemssen, T.

“…Cardiac autonomic abnormalities have been described in Parkinson’s disease and other extrapyramidal syndromes. To investigate baroreflex sensitivity as an…”
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MR-lymphangiography at 3.0T—a feasibility study by Notohamiprodjo, Mike, Baumeister, Ruediger G. H., Jakobs, Tobias F., Bauner, Kerstin U., Boehm, Holger F., Horng, Annie, Reiser, Maximilian F., Glaser, Christian, Herrmann, Karin A.

“…The purpose of this study was to establish and evaluate contrast-enhanced MR-lymphangiography (MRL) at 3.0T for detection and visualization of abnormalities of…”
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Sympathetic and parasympathetic activation in heart rate variability in male hypertensive patients under mental stress by RUEDIGER, H, SEIBT, R, SCHEUCH, K, KRAUSE, M, ALAM, S

“…Disturbed sympathetic and also parasympathetic activity of the autonomic nervous system points to pathological alterations in the cardiovascular system…”
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Acute autonomic effects of vitamins and fats in male smokers by Wright, C.I, Ruediger, H, Kroner, C.I, Janssen, B.J.A, Draijer, R

“…Background/Objectives: Vitamins can help improve cardiovascular control. In contrast, smoking works in the opposite fashion, reducing the baroreflex control of…”
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Microsurgical Lymphatic Vessel Transplantation by Baumeister, Ruediger G H, Mayo, Weiss, Notohamiprodjo, Mike, Wallmichrath, Jens, Springer, Stephanie, Frick, Andreas

“…Lymphedema often arises after a regional interruption during cancer treatment, for example after lymph node resection the axilla or the groin. Lymphatic…”
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Hard metal particles and lung disease: coincidence or causality? by Ruediger, H W

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High-Level, but Not Low-Level, Occupational Exposure to Inhaled Anesthetics Is Associated with Genotoxicity in the Micronucleus Assay by Wiesner, Gunther, Hoerauf, Klaus, Schroegendorfer, Klaus, Sobczynski, Pawel, Harth, Marion, Ruediger, Hugo W.

“…To minimize the possible health risks posed by waste anesthetic gases, the National Institute of Occupational Safety and Health (NIOSH) recommends exposure…”
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Primary lymphedema of the lower limb: the clinical utility of single photon emission computed tomography/CT by Weiss, Mayo, Baumeister, Ruediger G H, Frick, Andreas, Wallmichrath, Jens, Bartenstein, Peter, Rominger, Axel

“…The aim of this prospective study was to determine whether the additional use of the single photon emission computed tomography/CT (SPECT/CT) technique…”
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β-Alanine dipeptides as MC4R agonists by RUEL, Réjean, HERPIN, Timothy F, THIBAULT, Carl, GUIXUE YU, ZIMANYI, Ildiko Antal, POINDEXTER, Graham S, MACOR, John E, IBEN, Lawrence, GUANGLIN LUO, MARTEL, Alain, MASON, Helen, MATTSON, Gail, POIRIER, Brigitte, RUEDIGER, Edward H, SHI, Dan

“…beta-Alanine derivative 2 (IC(50)=16 nM) and related compounds were found to be potent MC4R agonists…”
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Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription by Frischauf, Irene, Litviňuková, Monika, Schober, Romana, Zayats, Vasilina, Svobodová, Barbora, Bonhenry, Daniel, Lunz, Victoria, Cappello, Sabrina, Tociu, Laura, Reha, David, Stallinger, Amrutha, Hochreiter, Anna, Pammer, Teresa, Butorac, Carmen, Muik, Martin, Groschner, Klaus, Bogeski, Ivan, Ettrich, Rüdiger H, Romanin, Christoph, Schindl, Rainer

“…The channel Orai1 requires Ca store depletion in the endoplasmic reticulum and an interaction with the Ca sensor STIM1 to mediate Ca signaling. Alterations in…”
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Variations of p53 in cultured fibroblasts of patients with lung cancer who have a presumed genetic predisposition by AUER, H, WARNCKE, K, NOWAK, D, KOOPS, F, JAEGER, U, KURZBAUER, R, RUEDIGER, H. W

“…The authors studied cultured skin fibroblasts of 64 patients with lung cancer for constitutive mutations of the p53 tumor suppressor gene by using polymerase…”
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Crystal structure of a novel domain of the motor subunit of the Type I restriction enzyme EcoR124 involved in complex assembly and DNA binding by Grinkevich, Pavel, Sinha, Dhiraj, Iermak, Iuliia, Guzanova, Alena, Weiserova, Marie, Ludwig, Jost, Mesters, Jeroen R., Ettrich, Rüdiger H.

“…Although EcoR124 is one of the better-studied Type I restriction-modification enzymes, it still presents many challenges to detailed analyses because of its…”
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Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors by Beaulieu, Francis, Ouellet, Carl, Ruediger, Edward H., Belema, Makonen, Qiu, Yuping, Yang, Xuejie, Banville, Jacques, Burke, James R., Gregor, Kurt R., MacMaster, John F., Martel, Alain, McIntyre, Kim W., Pattoli, Mark A., Zusi, F. Christopher, Vyas, Dolatrai

“…We have recently identified BMS-345541 ( 1) as a highly selective and potent inhibitor of IKK-2 (IC 50 = 0.30 μM), which however was considerably less potent…”
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2-Arylaminothiazoles as high-affinity corticotropin-Releasing factor 1 receptor (CRF 1R) antagonists: synthesis, binding studies and behavioral efficacy by Dubowchik, Gene M., Michne, Jodi A., Zuev, Dmitry, Schwartz, Wendy, Scola, Paul M., James, Clint A., Ruediger, Edward H., Pin, Sokhom S., Burris, Kevin D., Balanda, Lynn A., Gao, Qi, Wu, Dedong, Fung, Lawrence, Fiedler, Tracey, Browman, Kaitlin E., Taber, Matthew T., Zhang, Jie

“…2-Arylamino-4-trifluoromethyl-5-aminomethylthiazoles represent a novel series of high-affinity corticotropin releasing factor-1 receptor (CRF 1R) antagonists…”
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Synthesis and biological activity of the putative metabolites of the atypical antipsychotic agent tiospirone by Cipollina, Joseph A, Ruediger, Edward H, New, James S, Wire, Mary E, Shepherd, Timothy A, Smith, David W, Yevich, Joseph P

“…Putative oxidative metabolites of the lead antipsychotic agent tiospirone (1) were synthesized to assist in the identification of the authentic metabolic…”
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Technique and proof of patency of microsurgical lympho-lymphonodular anastomoses: A study in the rat model by Wallmichrath, Jens, Baumeister, Ruediger G. H., Deglmann, Claus J., Greiner, Axel, Heim, Sibylle, Frick, Andreas

“…Background: Lymphedemas due to local lymphatic blocks can be treated by microsurgical transplantation or transposition of lymphatic vessels. Here, the…”
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