Search Results - "Rueda, S"
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Live cell imaging of single RNA molecules with fluorogenic Mango II arrays
Published in Nature communications (09-03-2020)“…RNA molecules play vital roles in many cellular processes. Visualising their dynamics in live cells at single-molecule resolution is essential to elucidate…”
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Illicit drug use in sexual settings ('chemsex') and HIV/STI transmission risk behaviour among gay men in South London: findings from a qualitative study
Published in Sexually transmitted infections (01-12-2015)“…'Chemsex' is a colloquial term used in the UK that describes sex under the influence of psychoactive substances (typically crystal methamphetamine, mephedrone…”
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Motivations and values associated with combining sex and illicit drugs ('chemsex') among gay men in South London: findings from a qualitative study
Published in Sexually transmitted infections (01-05-2017)“…There is considerable public health concern about the combining of sex and illicit drugs (chemsex) among gay men. With a view to inform supportive therapeutic…”
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The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle
Published in PLoS pathogens (01-07-2023)“…Infections by Human T cell Leukaemia Virus type 1 (HTLV-1) persist for the lifetime of the host by integrating into the genome of CD4+ T cells. Proviral gene…”
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DNA stretching induces Cas9 off-target activity
Published in Nature structural & molecular biology (01-03-2019)“…CRISPR/Cas9 is a powerful genome-editing tool, but spurious off-target edits present a barrier to therapeutic applications. To understand how CRISPR/Cas9…”
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6
Structure and dynamics of the yeast SWR1-nucleosome complex
Published in Science (American Association for the Advancement of Science) (12-10-2018)“…The yeast SWR1 complex exchanges histone H2A in nucleosomes with Htz1 (H2A.Z in humans). The cryo-electron microscopy structure of the SWR1 complex bound to a…”
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Feasible integration in asphalt of piezoelectric cymbals for vibration energy harvesting
Published in Energy conversion and management (01-03-2016)“…A system based on piezoelectric cymbals embedded in asphalt for the first time is used as harvester for wasted vibrational energy produced by traffic. Energy…”
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Search and processing of Holliday junctions within long DNA by junction-resolving enzymes
Published in Nature communications (07-10-2022)“…Resolution of Holliday junctions is a critical intermediate step of homologous recombination in which junctions are processed by junction-resolving…”
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9
Optimal molecular crowding accelerates group II intron folding and maximizes catalysis
Published in Proceedings of the National Academy of Sciences - PNAS (20-11-2018)“…Unlike in vivo conditions, group II intron ribozymes are known to require high magnesium(II) concentrations ([Mg2+]) and high temperatures (42 °C) for folding…”
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10
Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer
Published in Nature communications (13-09-2019)“…Retroviral integrase can efficiently utilise nucleosomes for insertion of the reverse-transcribed viral DNA. In face of the structural constraints imposed by…”
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Kinetics of HTLV-1 reactivation from latency quantified by single-molecule RNA FISH and stochastic modelling
Published in PLoS pathogens (18-11-2019)“…The human T cell leukemia virus HTLV-1 establishes a persistent infection in vivo in which the viral sense-strand transcription is usually silent at a given…”
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Randomized Controlled Trial of Bovine Lactoferrin for Prevention of Sepsis and Neurodevelopment Impairment in Infants Weighing Less Than 2000 Grams
Published in The Journal of pediatrics (01-04-2020)“…To determine the effect of bovine lactoferrin on prevention of late-onset sepsis (LOS) and neurodevelopment delay. Randomized, double-blind, controlled trial…”
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The potential for quality assurance systems to save costs and lives: the case of early infant diagnosis of HIV
Published in Tropical medicine & international health (01-10-2020)“…Objectives Scaling up of point‐of‐care testing (POCT) for early infant diagnosis of HIV (EID) could reduce the large gap in infant testing. However, suboptimal…”
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Are allergic diseases and internalizing and externalizing behaviours in children related? A cross-sectional study
Published in European psychiatry (01-06-2022)“…Introduction The prevalence of allergies in children has grown in last few decades. Allergies are very often associated with physical, mental, and emotional…”
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Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC
Published in Cell communication and signaling (20-10-2023)“…When ectopically overexpressed, anticancer genes, such as TRAIL, PAR4 and ORCTL3, specifically destroy tumour cells without harming untransformed cells…”
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A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules
Published in Science advances (01-11-2019)“…Sister chromatid cohesion requires cohesin to act as a protein linker to hold chromatids together. How cohesin tethers chromatids remains poorly understood. We…”
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Effect of Phytase Level and Form on Broiler Performance, Tibia Characteristics, and Residual Fecal Phytate Phosphorus in Broilers from 1 to 21 Days of Age
Published in Animals (Basel) (01-08-2022)“…The present study evaluated the individual and combined effects of coated and uncoated phytase on broiler performance, tibia characteristics, and residual…”
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Conceptual design of BabyIAXO, the intermediate stage towards the International Axion Observatory
Published in The journal of high energy physics (01-05-2021)“…A bstract This article describes BabyIAXO, an intermediate experimental stage of the International Axion Observatory (IAXO), proposed to be sited at DESY. IAXO…”
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Lactoferrin concentration in breast milk of mothers of low-birth-weight newborns
Published in Journal of perinatology (01-05-2017)“…Objectives: Lactoferrin (LF) is a breast milk glycoprotein with protective effects against neonatal infections, mainly in premature and low-birth-weight (LBW)…”
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Health inequalities among the elderly in western Europe
Published in Journal of epidemiology and community health (1979) (01-06-2008)“…Background:This paper analyses gender inequalities in health status and in social determinants of health among the elderly in western Europe.Methods:Data came…”
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