Search Results - "Rue, Ryan W"

Repurposing Nitazoxanide for Potential Treatment of Rare Disease Lymphangioleiomyomatosis by Bähr, Stella, Rue, Ryan W, Smith, Carly J, Evans, Jillian F, Köster, Hubert, Krymskaya, Vera P, Pleimes, Dirk

“…Lymphangioleiomyomatosis (LAM) is a rare genetic lung disease. Unfortunately, treatment with the mTORC1 inhibitor Rapamycin only slows disease progression, and…”
Get full text

Inhibition of Growth of TSC2-Null Cells by a PI3K/mTOR Inhibitor but Not by a Selective MNK1/2 Inhibitor by Evans, Jilly F, Rue, Ryan W, Mukhitov, Alexander R, Obraztsova, Kseniya, Smith, Carly J, Krymskaya, Vera P

“…Lymphangioleiomyomatosis (LAM) is a rare metastatic cystic lung disease due to a mutation in a TSC tumor suppressor, resulting in hyperactive mTOR growth…”
Get full text

Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex by Kovalenko, Andrii, Sanin, Andres, Kosmas, Kosmas, Zhang, Long, Wang, Ji, Akl, Elie W, Giannikou, Krinio, Probst, Clemens K, Hougard, Thomas R, Rue, Ryan W, Krymskaya, Vera P, Asara, John M, Lam, Hilaire C, Kwiatkowski, David J, Henske, Elizabeth P, Filippakis, Harilaos

“…Lymphangioleiomyomatosis is a rare destructive lung disease affecting primarily women and is the primary lung manifestation of tuberous sclerosis complex…”
Get full text