Search Results - "Rudolf, Jana"

The DNA Repair Helicases XPD and FancJ Have Essential Iron-Sulfur Domains by Rudolf, Jana, Makrantoni, Vasso, Ingledew, W. John, Stark, Michael J.R., White, Malcolm F.

“…DNA helicases are essential components of the cellular machinery for DNA replication, recombination, repair, and transcription. The XPD and FancJ proteins are…”
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Crystal structure of a Trypanosoma brucei metacaspase by McLuskey, Karen, Rudolf, Jana, Proto, William R, Isaacs, Neil W, Coombs, Graham H, Moss, Catherine X, Mottram, Jeremy C

“…Metacaspases are distantly related caspase-family cysteine peptidases implicated in programmed cell death in plants and lower eukaryotes. They differ…”
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Proteolytic processing of QSOX1A ensures efficient secretion of a potent disulfide catalyst by Rudolf, Jana, Pringle, Marie A, Bulleid, Neil J

“…QSOX1 (quiescin sulfhydryl oxidase 1) efficiently catalyses the insertion of disulfide bonds into a wide range of proteins. The enzyme is mechanistically well…”
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NADPH Oxidases and Their Roles in Skin Homeostasis and Carcinogenesis by Rudolf, Jana, Raad, Houssam, Taieb, Alain, Rezvani, Hamid Reza

“…Skin protects the body from dehydration, pathogens, and external mutagens. NADPH oxidases are central components for regulating the cellular redox balance…”
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ERp18 regulates activation of ATF6α during unfolded protein response by Oka, Ojore Bv, van Lith, Marcel, Rudolf, Jana, Tungkum, Wanida, Pringle, Marie Anne, Bulleid, Neil J

“…Activation of the ATF6α signaling pathway is initiated by trafficking of ATF6α from the ER to the Golgi apparatus. Its subsequent proteolysis releases a…”
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The production of preconditioned freeze-dried Oenococcus oeni primes its metabolism to withstand environmental stresses encountered upon inoculation into wine by Matsumoto, Sayoko, Breniaux, Marion, Claisse, Olivier, Gotti, Clarisse, Bourassa, Sylvie, Droit, Arnaud, Deleris-Bou, Magali, Krieger, Sibylle, Weidmann, Stéphanie, Rudolf, Jana, Lucas, Patrick

“…Oenococcus oeni is the most resistant lactic acid bacteria species to the environmental stresses encountered in wine, particularly the acidity, presence of…”
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ER p18 regulates activation of ATF 6α during unfolded protein response by Oka, Ojore BV, van Lith, Marcel, Rudolf, Jana, Tungkum, Wanida, Pringle, Marie Anne, Bulleid, Neil J

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Loss of Epidermal HIF-1α Blocks UVB-Induced Tumorigenesis by Affecting DNA Repair Capacity and Oxidative Stress by Mahfouf, Walid, Hosseini, Mohsen, Muzotte, Elodie, Serrano-Sanchez, Martin, Dousset, Lea, Moisan, François, Rachidi, Walid, Taieb, Alain, Rudolf, Jana, Rezvani, Hamid Reza

“…HIF-1α is constitutively expressed in mouse and human epidermis. It plays a crucial role in skin physiology, including the response of keratinocytes to UVR…”
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Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium by Mardaryev, Andrei N, Liu, Bo, Rapisarda, Valentina, Poterlowicz, Krzysztof, Malashchuk, Igor, Rudolf, Jana, Sharov, Andrey A, Jahoda, Colin A, Fessing, Michael Y, Benitah, Salvador A, Xu, Guo-Liang, Botchkarev, Vladimir A

“…During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into…”
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helicase XPD unwinds bubble structures and is not stalled by DNA lesions removed by the nucleotide excision repair pathway by Rudolf, Jana, Rouillon, Christophe, Schwarz-Linek, Ulrich, White, Malcolm F

“…Xeroderma pigmentosum factor D (XPD) is a 5'-3' superfamily 2 helicase and the founding member of a family of DNA helicases with iron-sulphur cluster domains…”
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ERp18 regulates activation of ATF6α during unfolded protein response by Oka, Ojore BV, van Lith, Marcel, Rudolf, Jana, Tungkum, Wanida, Pringle, Marie Anne, Bulleid, Neil J

“…Activation of the ATF6α signaling pathway is initiated by trafficking of ATF6α from the ER to the Golgi apparatus. Its subsequent proteolysis releases a…”
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Structure of the DNA Repair Helicase XPD by Liu, Huanting, Rudolf, Jana, Johnson, Kenneth A., McMahon, Stephen A., Oke, Muse, Carter, Lester, McRobbie, Anne-Marie, Brown, Sara E., Naismith, James H., White, Malcolm F.

“…The XPD helicase (Rad3 in Saccharomyces cerevisiae) is a component of transcription factor IIH (TFIIH), which functions in transcription initiation and…”
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Structure of an XPF endonuclease with and without DNA suggests a model for substrate recognition by Newman, Matthew, Murray-Rust, Judith, Lally, John, Rudolf, Jana, Fadden, Andrew, Knowles, Philip P, White, Malcolm F, McDonald, Neil Q

“…The XPF/Mus81 structure‐specific endonucleases cleave double‐stranded DNA (dsDNA) within asymmetric branched DNA substrates and play an essential role in…”
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Design and evaluation of Trypanosoma brucei metacaspase inhibitors by Berg, Maya, Veken, Pieter Van der, Joossens, Jurgen, Muthusamy, Venkatraj, Breugelmans, Matthias, Moss, Catherine X., Rudolf, Jana, Cos, Paul, Coombs, Graham H., Maes, Louis, Haemers, Achiel, Mottram, Jeremy C., Augustyns, Koen

“…We present the first inhibitors of metacaspase 2 of Trypanosoma brucei with low micromolar enzymatic activity. These compounds possess modest antiparasitic…”
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Structure of the heterotrimeric PCNA from Sulfolobus solfataricus by Williams, Gareth J., Johnson, Kenneth, Rudolf, Jana, McMahon, Stephen A., Carter, Lester, Oke, Muse, Liu, Huanting, Taylor, Garry L., White, Malcolm F., Naismith, James H.

“…PCNA is a ring‐shaped protein that encircles DNA, providing a platform for the association of a wide variety of DNA‐processing enzymes that utilize the PCNA…”
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Characterisation of xpd from sulfolobus acidocaldarius: an iron-sulphur cluster containing dna repair helicase by Rudolf, Jana

“…DNA is constantly damaged by a variety of exogenous and endogenous sources. To maintain the integrity of the genome, different DNA repair mechanisms have…”
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Pancreatic exocrine insufficiency, diabetes mellitus and serum nutritional markers after acute pancreatitis by Vujasinovic, Miroslav, Tepes, Bojan, Makuc, Jana, Rudolf, Sasa, Zaletel, Jelka, Vidmar, Tjasa, Seruga, Maja, Birsa, Bostjan

“…AIM:To investigate impairment and clinical significance of exocrine and endocrine pancreatic function in patients after acute pancreatitis(AP).METHODS:Patients…”
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The Professor March and Rag by Rudolf, Jana, Lamb, Marvin

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The Idea Bank: Contemporary Choral Works That Work by Rudolf, Jana, Zumbrunn, Karen Fanta, Sollom, Ralph D., Whittemore, Joan M.

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