Search Results - "Rudokas, Michael"
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Impossible Decisions
Published in American scientist (01-11-2022)“…Scientific researchers are becoming increasingly dissatisfied with the workplace environment often associated with academic positions. Nature's 2021 Salary and…”
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Role of AMPK pathway inactivation in high fat diet related cardiac electrophysiological remodeling
Published in Biophysical journal (10-02-2023)Get full text
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Mitochondrial network remodeling of the diabetic heart: implications to ischemia related cardiac dysfunction
Published in Cardiovascular diabetology (18-07-2024)“…Mitochondria play a central role in cellular energy metabolism, and their dysfunction is increasingly recognized as a critical factor in the pathogenesis of…”
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The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells
Published in The Journal of physiology (15-07-2017)“…Key points The angiotensin II receptor type 1b (AT1Rb) is the primary sensor of intraluminal pressure in cerebral arteries. Pressure or membrane‐stretch…”
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Advanced Technologies in Radiation Research
Published in Radiation research (01-04-2024)“…The U.S. Government is committed to maintaining a robust research program that supports a portfolio of scientific experts who are investigating the biological…”
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Compartmentation of β2‐adrenoceptor stimulated cAMP responses by phosphodiesterase types 2 and 3 in cardiac ventricular myocytes
Published in British journal of pharmacology (01-04-2021)“…Background and Purpose In cardiac myocytes, cyclic AMP (cAMP) produced by both β1‐ and β2‐adrenoceptors increases L‐type Ca2+ channel activity and myocyte…”
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SPEAR Trial: Smartphone Pediatric ElectrocARdiogram Trial
Published in PloS one (21-08-2015)“…Smartphone-enabled ECG devices have the potential to improve patient care by enabling remote ECG assessment of patients with potential and diagnosed…”
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Compartmentation of β 2 -adrenoceptor stimulated cAMP responses by phosphodiesterase types 2 and 3 in cardiac ventricular myocytes
Published in British journal of pharmacology (01-04-2021)“…In cardiac myocytes, cyclic AMP (cAMP) produced by both β - and β -adrenoceptors increases L-type Ca channel activity and myocyte contraction. However, only…”
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Reveal LINQ Versus Reveal XT Implantable Loop Recorders: Intra- and Post-Procedural Comparison
Published in The Journal of pediatrics (01-08-2017)“…To compare the procedure, recovery, hospitalization times, and costs along with patient/parent satisfaction after newer-generation cardiac implantable loop…”
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Mitochondrial A‐kinase anchoring proteins in cardiac ventricular myocytes
Published in Physiological reports (01-09-2021)“…Compartmentation of cAMP signaling is a critical factor for maintaining the integrity of receptor‐specific responses in cardiac myocytes. This phenomenon…”
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The Xenopus oocyte cut-open vaseline gap voltage-clamp technique with fluorometry
Published in Journal of visualized experiments (11-03-2014)“…The cut-open oocyte Vaseline gap (COVG) voltage clamp technique allows for analysis of electrophysiological and kinetic properties of heterologous ion channels…”
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Alpha-Adrenergic Regulation of Camp in Ventricular Cardiac Myocytes
Published in Biophysical journal (12-02-2021)Get full text
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Impossible Decisions: Institutions should stop making doctoral students choose between work and health
Published in American scientist (01-11-2022)Get full text
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Abstract P3052: Dysregulation Of The Ampk-drp1 Axis Promotes Pathophysiological Remodeling Of Mitochondrial Ultrastructure And Ventricular Electrophysiological Function
Published in Circulation research (05-08-2022)“…AMP-activated protein kinase (AMPK), a master metabolic sensor, plays a central role in the regulation of mitochondrial (mito) function. AMPK activation…”
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Quantitative Assessment of Mitochondrial Morphology and Electrophysiological Function in the Diabetic Heart
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Mitochondria within a cardiomyocyte form a highly dynamic network that undergoes fusion and fission events in response to acute and chronic stressors, such as…”
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Phosphodiesterase 2 and 3 Regulate Compartmentalized Beta2-Adrenergic Receptor Camp Signaling
Published in Biophysical journal (07-02-2020)Get full text
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The Complexities of cAMP Signaling in the Heart
Published 01-01-2021“…The autonomic nervous system regulates heart function to meet the metabolic demands of the body. The sympathetic branch of the autonomic nervous system…”
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Coronary sinus morphology in pediatric patients with supraventricular tachycardia
Published in Journal of interventional cardiac electrophysiology (01-03-2018)“…Purpose The anatomic basis of atrioventricular node reentrant tachycardia (AVNRT) remains incompletely characterized in children. Differences in coronary sinus…”
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