Search Results - "Rudnick, Jeremy"

A Phase I Study of Autologous Dendritic Cell Vaccine Pulsed with Allogeneic Stem-like Cell Line Lysate in Patients with Newly Diagnosed or Recurrent Glioblastoma by Hu, Jethro L, Omofoye, Oluwaseun A, Rudnick, Jeremy D, Kim, Sungjin, Tighiouart, Mourad, Phuphanich, Surasak, Wang, Hongqiang, Mazer, Mia, Ganaway, Toni, Chu, Ray M, Patil, Chirag G, Black, Keith L, Shiao, Stephen L, Wang, Rongfu, Yu, John S

“…Glioblastoma (GBM) is a heterogeneous malignancy with multiple subpopulations of cancer cells present within any tumor. We present the results of a phase I…”
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EGFR/ErbB2-Targeting Lapatinib Therapy for Aggressive Prolactinomas by Cooper, Odelia, Bonert, Vivien S, Rudnick, Jeremy, Pressman, Barry D, Lo, Janet, Salvatori, Roberto, Yuen, Kevin C J, Fleseriu, Maria, Melmed, Shlomo

“…Abstract Context Approximately 10% to 20% of prolactinomas are resistant to dopamine agonist therapy. The ErbB signaling pathway may drive aggressive…”
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Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma by Phuphanich, Surasak, Wheeler, Christopher J., Rudnick, Jeremy D., Mazer, Mia, Wang, HongQian, Nuño, Miriam A., Richardson, Jaime E., Fan, Xuemo, Ji, Jianfei, Chu, Ray M., Bender, James G., Hawkins, Elma S., Patil, Chirag G., Black, Keith L., Yu, John S.

“…Background This study evaluated the safety and immune responses to an autologous dendritic cell vaccine pulsed with class I peptides from tumor-associated…”
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Atypical and anaplastic meningiomas treated with bevacizumab by Nayak, Lakshmi, Iwamoto, Fabio M., Rudnick, Jeremy D., Norden, Andrew D., Lee, Eudocia Quant, Drappatz, Jan, Omuro, Antonio, Kaley, Thomas J.

“…Atypical and anaplastic (WHO Grades II and III) meningiomas are aggressive tumors, and patients often progress despite surgery and radiation. There is no known…”
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Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk by Sun, Tao, Patil, Rameshwar, Galstyan, Anna, Klymyshyn, Dmytro, Ding, Hui, Chesnokova, Alexandra, Cavenee, Webster K, Furnari, Frank B, Ljubimov, Vladimir A, Shatalova, Ekaterina S, Wagner, Shawn, Li, Debiao, Mamelak, Adam N, Bannykh, Serguei I, Patil, Chirag G, Rudnick, Jeremy D, Hu, Jethro, Grodzinski, Zachary B, Rekechenetskiy, Arthur, Falahatian, Vida, Lyubimov, Alexander V, Chen, Yongmei L, Leoh, Lai S, Daniels-Wells, Tracy R, Penichet, Manuel L, Holler, Eggehard, Ljubimov, Alexander V, Black, Keith L, Ljubimova, Julia Y

“…There is an unmet need for the treatment of glioblastoma multiforme (GBM). The extracellular matrix, including laminins, in the tumor microenvironment is…”
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ZEB1 loss increases glioma stem cell tumorigenicity and resistance to chemoradiation by Hanna, George K, Madany, Mecca, Tay, Angelique Sao-Mai Sy, Edwards, Lincoln A, Kim, Sungjin, Michael, Justin S, Nuno, Miriam, Thomas, Tom, Li, Aiguo, Berel, Dror, Black, Keith L, Fan, Xuemo, Zhang, Wei, Rudnick, Jeremy D, Wang, Rongfu, Yu, John S

“…Glioblastoma has been known to be resistant to chemotherapy and radiation, whereas the underlying mechanisms of resistance have not been fully elucidated. The…”
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A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant glioma by Rudnick, Jeremy D., Sarmiento, J. Manuel, Uy, Benjamin, Nuno, Miriam, Wheeler, Christopher J., Mazer, Mia J., Wang, Hongqiang, Hu, Jethro L., Chu, Ray M., Phuphanich, Surasak, Black, Keith L., Yu, John S.

“…•High grade gliomas are associated with a poor prognosis, even with surgery followed by radiation therapy and chemotherapy.•Gliadel Wafer treatments have shown…”
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Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era by Carico, Christine, Nuño, Miriam, Mukherjee, Debraj, Elramsisy, Adam, Dantis, Jocelynn, Hu, Jethro, Rudnick, Jeremy, Yu, John S, Black, Keith L, Bannykh, Serguei I, Patil, Chirag G

“…Pre-temozolomide studies demonstrated that loss of the tumor suppressor gene PTEN held independent prognostic significance in GBM patients. We investigated…”
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Clinical response to pazopanib in a patient with endolymphatic sac tumor not associated with von Hippel-Lindau syndrome by Nelson, Thomas, Hu, Jethro, Bannykh, Serguei, Fan, Xuemo, Rudnick, Jeremy, Vail, Eric

“…Endolymphatic sac tumors (ELSTs) are rare, locally invasive, vascular tumors of the temporal bone. These lesions are associated with von Hippel-Lindau syndrome…”
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Retrospective analysis of the tolerability and activity of lacosamide in patients with brain tumors: clinical article by Saria, Marlon G, Corle, Courtney, Hu, Jethro, Rudnick, Jeremy D, Phuphanich, Surasak, Mrugala, Maciej M, Crew, Laura K, Bota, Daniela A, Dan Fu, Beverly, Kim, Ryan Y, Brown, Tiffany, Feely, Homira, Brechlin, Joanne, Brown, Bradley D, Drappatz, Jan, Wen, Patrick Y, Chen, Clark C, Carter, Bob, Lee, Jong Woo, Kesari, Santosh

“…The object of this study was to determine the tolerability and activity of lacosamide in patients with brain tumors. The authors reviewed the medical records…”
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Adult Brainstem Glioblastoma Multiforme: Long-term Survivor by Barnard, Zachary R, Drazin, Doniel, Bannykh, Serguei I, Rudnick, Jeremy D, Chu, Ray M

“…Adult, malignant brainstem gliomas are rare entities that often cause treatment conundrums due to the difficulty of surgical resection and, therefore, the…”
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BIOM-42. RESPONSE TO DABRAFENIB/TRAMETINIB IN A PATIENT WITH WHO-CNS GRADE 3 BRAF V600E-MUTATED PLEOMORPHIC XANTHOASTROCYTOMA by Alalami, Huda, Bannykh, Serguei, Vail, Eric, Patil, Chirag, Rudnick, Jeremy, Hu, Jethro

“…Abstract BACKGROUND Pleomorphic xanthoastrocytoma (PXA) is a rare central nervous system tumor. Mutations in BRAF V600E are present in 60-80% of cases. While…”
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RARE-17. LENALIDOMIDE AS TREATMENT FOR RELAPSED OR REFRACTORY PRIMARY CNS LYMPHOMA: A SINGLE INSTITUTIONAL EXPERIENCE by Molaie, Donna, Hu, Jethro, Rudnick, Jeremy

“…Abstract BACKGROUND Primary CNS Lymphoma (PCNSL) is an aggressive form of diffuse large B-cell lymphoma (DLBCL). Lenalidomide is an immunomodulatory agent…”
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Isolated bilateral globus pallidus infarcts in a patient with aortic dissection and Nitroprusside-induced hypotension: A case report (P5.043) by Esch, Megan, Diaz, Frank, Rudnick, Jeremy

“…Abstract only…”
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Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial by Chiocca, E Antonio, Yu, John S, Lukas, Rimas V, Solomon, Isaac H, Ligon, Keith L, Nakashima, Hiroshi, Triggs, Daniel A, Reardon, David A, Wen, Patrick, Stopa, Brittany M, Naik, Ajay, Rudnick, Jeremy, Hu, Jethro L, Kumthekar, Priya, Yamini, Bakhtiar, Buck, Jill Y, Demars, Nathan, Barrett, John A, Gelb, Arnold B, Zhou, John, Lebel, Francois, Cooper, Laurence J N

“…Human interleukin-12 (hIL-12) is a cytokine with anticancer activity, but its systemic application is limited by toxic inflammatory responses. We assessed the…”
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Clinical Response to Pazopanib in a Patient with Endolymphatic Sac Tumor Not Associated with von Hippel-Lindau Syndrome (63) by Nelson, Thomas, Bannykh, Serguei, Fan, Xuemo, Rudnick, Jeremy, Vail, Eric, Hu, Jethro

“…Abstract only…”
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Lenalidomide as treatment for relapsed or refractory primary CNS lymphoma: A single institutional experience by Molaie, Donna M, Hu, Jethro Lisien, Rudnick, Jeremy David

“…Abstract only…”
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The ketogenic diet plus standard of care for adults with recently diagnosed glioblastoma: Results from a phase 1 trial by Amaral, Lj, Gresham, Gillian, Kim, Sungjin, Tighiouart, Mourad, Nelson, Thomas, Welborn, Amelia, Lockshon, Laura, Noorvash, Brandon, Rudnick, Jeremy David, Irwin, Scott A, Freedland, Stephen J., Hu, Jethro Lisien

“…2076 Background: Facing limited treatment options, brain tumor patients are often highly motivated to use complementary therapies, including diet, to help…”
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DIET2TREAT: A randomized, multi-center, phase 2 trial of a ketogenic diet vs standard dietary guidance in combination with standard-of-care treatment for patients with newly diagnosed glioblastoma by Amaral, LJ, Gresham, Gillian, Butowski, Nicholas A., Peters, Katherine B., Sharma, Akanksha, Fonkem, Ekokobe, Chi, Jen-Tsan, Kesari, Santosh, Lin, Pao-hwa, Shiao, Stephen Lawrence, Tighiouart, Mourad, You, Sungyong, Rudnick, Jeremy David, Freedland, Stephen J., Hu, Jethro Lisien

“…TPS2103 Background: Presented with a dismal prognosis and limited treatment options, many glioblastoma (GBM) patients seek complementary interventions. Of…”
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Remote monitoring of sleep activity in patients diagnosed with glioblastoma by Noorvash, Brandon, Amaral, L J, Nelson, Thomas, Rudnick, Jeremy David, Irwin, Scott A, Freedland, Stephen J., Gresham, Gillian, Hu, Jethro Lisien

“…e14036 Background: Sleep disturbance is a common symptom experienced in patients diagnosed with glioblastoma (GBM) and has been correlated with poor physical…”
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