BioNSi: A Discrete Biological Network Simulator Tool

Modeling and simulation of biological networks is an effective and widely used research methodology. The Biological Network Simulator (BioNSi) is a tool for modeling biological networks and simulating their discrete-time dynamics, implemented as a Cytoscape App. BioNSi includes a visual representati...

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Bibliographic Details
Published in:	Journal of proteome research Vol. 15; no. 8; pp. 2871 - 2880
Main Authors:	Rubinstein, Amir, Bracha, Noga, Rudner, Liat, Zucker, Noga, Sloin, Hadas E, Chor, Benny
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 05-08-2016
Subjects:	Computer Simulation Internet Models, Biological Software discrete models modeling simulation biological networks
Online Access:	Get full text
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Summary:	Modeling and simulation of biological networks is an effective and widely used research methodology. The Biological Network Simulator (BioNSi) is a tool for modeling biological networks and simulating their discrete-time dynamics, implemented as a Cytoscape App. BioNSi includes a visual representation of the network that enables researchers to construct, set the parameters, and observe network behavior under various conditions. To construct a network instance in BioNSi, only partial, qualitative biological data suffices. The tool is aimed for use by experimental biologists and requires no prior computational or mathematical expertise. BioNSi is freely available at http://bionsi.wix.com/bionsi, where a complete user guide and a step-by-step manual can also be found.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1535-3893 1535-3907
DOI:	10.1021/acs.jproteome.6b00278