Search Results - "Rudloff, Ina"

Clinical associations of IL-10 and IL-37 in systemic lupus erythematosus by Godsell, Jack, Rudloff, Ina, Kandane-Rathnayake, Rangi, Hoi, Alberta, Nold, Marcel F., Morand, Eric F., Harris, James

“…Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the development of autoantibodies to nuclear antigens and inflammatory…”
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Monocytes and dendritic cells are the primary sources of interleukin 37 in human immune cells by Rudloff, Ina, Cho, Steven X., Lao, Jason C., Ngo, Devi, McKenzie, Matthew, Nold‐Petry, Claudia A., Nold, Marcel F.

“…IL‐37 is produced and secreted by antigen‐presenting cells, including monocytes and DCs, where IL‐37 may act as an alarmin. The interleukin (IL)‐1 family…”
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Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities by Cho, Steven X., Rudloff, Ina, Lao, Jason C., Pang, Merrin A., Goldberg, Rimma, Bui, Christine B., McLean, Catriona A., Stock, Magdalena, Klassert, Tilman E., Slevogt, Hortense, Mangan, Niamh E., Cheng, Wei, Fischer, Doris, Gfroerer, Stefan, Sandhu, Manjeet K., Ngo, Devi, Bujotzek, Alexander, Lariviere, Laurent, Schumacher, Felix, Tiefenthaler, Georg, Beker, Friederike, Collins, Clare, Kamlin, C. Omar F., König, Kai, Malhotra, Atul, Tan, Kenneth, Theda, Christiane, Veldman, Alex, Ellisdon, Andrew M., Whisstock, James C., Berger, Philip J., Nold-Petry, Claudia A., Nold, Marcel F.

“…Necrotizing enterocolitis (NEC) is a severe, currently untreatable intestinal disease that predominantly affects preterm infants and is driven by poorly…”
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Interleukin-1 receptor antagonist prevents murine bronchopulmonary dysplasia induced by perinatal inflammation and hyperoxia by Nold, Marcel F., Mangan, Niamh E., Rudioff, Ina, Cho, Steven X., Shariatian, Nikeh, Samarasinghe, Thilini D., Skuza, Elizabeth M., Pedersen, John, Veldman, Alex, Berger, Philip J., Nold-Petry, Claudia A.

“…Bronchopulmonary dysplasia (BPD) is a common lung disease of premature infants, with devastating short-and long-term consequences. The pathogenesis of BPD is…”
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Circulating Interleukin-37 Levels in Healthy Adult Humans - Establishing a Reference Range by Santarelli, Danielle M, Vincent, Fabien B, Rudloff, Ina, Nold-Petry, Claudia A, Nold, Marcel F, Russo, Marc A

“…Interleukin (IL)-37 has an important function in limiting excessive inflammation. Its expression is increased in numerous inflammatory and autoimmune…”
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Interleukin-1 Receptor Antagonist Protects Newborn Mice Against Pulmonary Hypertension by Bui, Christine B, Kolodziej, Magdalena, Lamanna, Emma, Elgass, Kirstin, Sehgal, Arvind, Rudloff, Ina, Schwenke, Daryl O, Tsuchimochi, Hirotsugu, Kroon, Maurice A G M, Cho, Steven X, Maksimenko, Anton, Cholewa, Marian, Berger, Philip J, Young, Morag J, Bourke, Jane E, Pearson, James T, Nold, Marcel F, Nold-Petry, Claudia A

“…Pulmonary hypertension secondary to bronchopulmonary dysplasia (BPD-PH) represents a major complication of BPD in extremely preterm infants for which there are…”
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Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study by Kronenberger, Bernd, Rudloff, Ina, Bachmann, Malte, Brunner, Friederike, Kapper, Lisa, Filmann, Natalie, Waidmann, Oliver, Herrmann, Eva, Pfeilschifter, Josef, Zeuzem, Stefan, Piiper, Albrecht, Mühl, Heiko

“…Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage…”
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Parsing the IL-37-Mediated Suppression of Inflammasome Function by Rudloff, Ina, Ung, Holly K, Dowling, Jennifer K, Mansell, Ashley, D'Andrea, Laura, Ellisdon, Andrew M, Whisstock, James C, Berger, Philip J, Nold-Petry, Claudia A, Nold, Marcel F

“…Interleukin (IL)-37 is a member of the IL-1 family of cytokines. Although its broad anti-inflammatory properties are well described, the effects of IL-37 on…”
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Remifentanil ameliorates intestinal ischemia-reperfusion injury by Cho, Steven S C, Rudloff, Ina, Berger, Philip J, Irwin, Michael G, Nold, Marcel F, Cheng, Wei, Nold-Petry, Claudia A

“…Intestinal ischemia-reperfusion injury (IRI) can occur in clinical scenarios such as organ transplantation, trauma and cardio-pulmonary bypass, as well as in…”
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Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 by Bachmann, Malte, Horn, Katharina, Rudloff, Ina, Goren, Itamar, Holdener, Martin, Christen, Urs, Darsow, Nicole, Hunfeld, Klaus-Peter, Koehl, Ulrike, Kind, Peter, Pfeilschifter, Josef, Kraiczy, Peter, Mühl, Heiko

“…If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine…”
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IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction by Nold-Petry, Claudia A, Lo, Camden Y, Rudloff, Ina, Elgass, Kirstin D, Li, Suzhao, Gantier, Michael P, Lotz-Havla, Amelie S, Gersting, Søren W, Cho, Steven X, Lao, Jason C, Ellisdon, Andrew M, Rotter, Björn, Azam, Tania, Mangan, Niamh E, Rossello, Fernando J, Whisstock, James C, Bufler, Philip, Garlanda, Cecilia, Mantovani, Alberto, Dinarello, Charles A, Nold, Marcel F

“…IL-37 is a member of the IL-1 family with profound anti-inflammatory functions. Nold and colleagues identify the receptor for IL-37 and clarify the molecular…”
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Understanding respiratory microbiome-immune system interactions in health and disease by Di Simone, Sara K, Rudloff, Ina, Nold-Petry, Claudia A, Forster, Samuel C, Nold, Marcel F

“…Interactions between the developing microbiome and maturing immune system in early life are critical for establishment of a homeostasis beneficial to both host…”
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Thirteen years to get from b to a: one of the neglected isoforms of IL-37 enters the stage by Cho, Steven X., Rudloff, Ina, Ellisdon, Andrew M., Nold-Petry, Claudia A., Nold, Marcel F.

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Airway Remodeling and Hyperreactivity in a Model of Bronchopulmonary Dysplasia and Their Modulation by IL-1 Receptor Antagonist by Royce, Simon G, Nold, Marcel F, Bui, Christine, Donovan, Chantal, Lam, Maggie, Lamanna, Emma, Rudloff, Ina, Bourke, Jane E, Nold-Petry, Claudia A

“…Bronchopulmonary dysplasia (BPD) is a chronic disease of extreme prematurity that has serious long-term consequences including increased asthma risk. We…”
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Refining anti‐inflammatory therapy strategies for bronchopulmonary dysplasia by Rudloff, Ina, Cho, Steven X., Bui, Christine B., McLean, Catriona, Veldman, Alex, Berger, Philip J., Nold, Marcel F., Nold‐Petry, Claudia A.

“…Bronchopulmonary dysplasia (BPD) is a severe lung disease of preterm infants, which is characterized by fewer, enlarged alveoli and increased inflammation. BPD…”
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Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants by Lao, Jason C, Bui, Christine B, Pang, Merrin A, Cho, Steven X, Rudloff, Ina, Elgass, Kirstin, Schröder, Jan, Maksimenko, Anton, Mangan, Niamh E, Starkey, Malcolm R, Skuza, Elisabeth M, Sun, Yu B Y, Beker, Friederike, Collins, Clare L, Kamlin, Omar F, König, Kai, Malhotra, Atul, Tan, Kenneth, Theda, Christiane, Young, Morag J, McLean, Catriona A, Wilson, Nicholas J, Sehgal, Arvind, Hansbro, Philip M, Pearson, James T, Polo, Jose M, Veldman, Alex, Berger, Philip J, Nold-Petry, Claudia A, Nold, Marcel F

“…Postnatal maturation of the immune system is poorly understood, as is its impact on illnesses afflicting term or preterm infants, such as bronchopulmonary…”
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Rare variants in non-coding regulatory regions of the genome that affect gene expression in systemic lupus erythematosus by Jones, Sarah A., Cantsilieris, Stuart, Fan, Huapeng, Cheng, Qiang, Russ, Brendan E., Tucker, Elena J., Harris, James, Rudloff, Ina, Nold, Marcel, Northcott, Melissa, Dankers, Wendy, Toh, Andrew E. J., White, Stefan J., Morand, Eric F.

“…Personalized medicine approaches are increasingly sought for diseases with a heritable component. Systemic lupus erythematosus (SLE) is the prototypic…”
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IL-32 promotes angiogenesis by Nold-Petry, Claudia A, Rudloff, Ina, Baumer, Yvonne, Ruvo, Menotti, Marasco, Daniela, Botti, Paolo, Farkas, Laszlo, Cho, Steven X, Zepp, Jarod A, Azam, Tania, Dinkel, Hannah, Palmer, Brent E, Boisvert, William A, Cool, Carlyne D, Taraseviciene-Stewart, Laima, Heinhuis, Bas, Joosten, Leo A B, Dinarello, Charles A, Voelkel, Norbert F, Nold, Marcel F

“…IL-32 is a multifaceted cytokine with a role in infections, autoimmune diseases, and cancer, and it exerts diverse functions, including aggravation of…”
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Molecular signature of interleukin-22 in colon carcinoma cells and organoid models by Rudloff, Ina, Jardé, Thierry, Bachmann, Malte, Elgass, Kirstin D., Kerr, Genevieve, Engel, Rebekah, Richards, Elizabeth, Oliva, Karen, Wilkins, Simon, McMurrick, Paul J., Abud, Helen E., Mühl, Heiko, Nold, Marcel F.

“…Interleukin (IL)-22 activates STAT (signal transducer and activator of transcription) 3 and antiapoptotic and proproliferative pathways; but beyond this, the…”
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Mechanisms of Rapid Induction of Interleukin-22 in Activated T Cells and Its Modulation by Cyclosporin A by Rudloff, Ina, Bachmann, Malte, Pfeilschifter, Josef, Mühl, Heiko

“…IL-22 is an immunoregulatory cytokine displaying pathological functions in models of autoimmunity like experimental psoriasis. Understanding molecular…”
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