Search Results - "Rudikoff, S"

Immune System Impairment and Hepatic Fibrosis in Mice Lacking the Dioxin- Binding Ah Receptor by Fernandez-Salguero, Pedro, Pineau, Thierry, Hilbert, David M., McPhail, Timothy, Susanna S. T. Lee, Kimura, Shioko, Nebert, Daniel W., Rudikoff, Stuart, Ward, Jerrold M., Gonzalez, Frank J.

“…The aryl hydrocarbon (Ah) receptor (AHR) mediates many carcinogenic and teratogenic effects of environmentally toxic chemicals such as dioxin. An AHR-deficient…”
Get full text

Interleukin 6 is essential for in vivo development of B lineage neoplasms by Hilbert, D M, Kopf, M, Mock, B A, Köhler, G, Rudikoff, S

“…Interleukin (IL) 6 has been suggested to be the major cytokine responsible for proliferation of neoplastic plasma cells in both human myeloma and mouse…”
Get full text

Purification and Characterization of a Newly Identified Growth Factor Specific for Epithelial Cells by Rubin, Jeffrey S., Osada, Hiroyuki, Finch, Paul W., Taylor, William G., Rudikoff, Stuart, Aaronson, Stuart A.

“…A growth factor specific for epithelial cells was identified in conditioned medium of a human embryonic lung fibroblast cell line, The factor, provisionally…”
Get full text

Expression of PTEN in PTEN-deficient multiple myeloma cells abolishes tumor growth in vivo by GE, N.-L, RUDIKOFF, S

“…Biochemical abnormalities associated with the development of multiple myeloma have been difficult to define especially in terms of demonstrating an in vivo…”
Get full text

Sequence and structure of Clp P, the proteolytic component of the ATP-dependent Clp protease of Escherichia coli by Maurizi, M R, Clark, W P, Katayama, Y, Rudikoff, S, Pumphrey, J, Bowers, B, Gottesman, S

“…The ATP-dependent Clp protease of Escherichia coli contains two dissimilar components: the Clp A regulatory polypeptide, with two ATP binding sites and…”
Get full text

The two-component, ATP-dependent Clp protease of Escherichia coli. Purification, cloning, and mutational analysis of the ATP-binding component by Katayama, Y, Gottesman, S, Pumphrey, J, Rudikoff, S, Clark, W P, Maurizi, M R

“…The ATP-binding component (Component II, hereafter referred to as ClpA) of a two-component, ATP-dependent protease from Escherichia coli has been purified to…”
Get full text

VH genes encoding the immune response to beta‐(1,6)‐galactan: somatic mutation in IgM molecules by Hartman, A.B., Rudikoff, S.

“…The immune response to beta‐(1,6)‐galactan in the BALB/c mouse has been well characterized and includes the amino acid sequence determination of 13 monoclonal…”
Get full text

Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate by Simons, S S, Pumphrey, J G, Rudikoff, S, Eisen, H J

“…Recent results using proteases suggest that dexamethasone 21-mesylate (Dex-Mes) labeling of the rat hepatoma tissue culture (HTC) cell glucocorticoid receptor…”
Get full text

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma by Qiang, Ya-Wei, Barlogie, Bart, Rudikoff, Stuart, Shaughnessy, John D

“…Abstract Expression of the Wnt signaling inhibitor, DKK1 by multiple myeloma cells is correlated with lytic bone disease in multiple myeloma. However, the…”
Get full text

Purification and NH2-terminal sequence of a plasmacytoma growth factor derived from the murine macrophage cell line P388D1 by Nordan, RP, Pumphrey, JG, Rudikoff, S

“…Plasmacytoma growth factor (PCT-GF), a putative macrophage-derived lymphokine essential for the in vitro viability and proliferation of early generation…”
Get full text

In vitro Culture of Primary Plasmacytomas Requires Stromal Cell Feeder Layers by Degrassi, Alberto, Hilbert, David M., Rudikoff, Stuart, Anderson, Arthur O., Potter, Michael, Coon, Hayden G.

“…Attempts to grow primary murine plasmacytomas in vitro have, to date, been largely unsuccessful. In this study, we demonstrate that long-term in vitro growth…”
Get full text

T Cells Induce Terminal Differentiation of Transformed B Cells to Mature Plasma Cell Tumors by Hilbert, David M., Shen, Ming-Yan, Rapp, Ulf R., Rudikoff, Stuart

“…Major interest in the analysis of mature plasma cell neoplasias of mice and humans has focused on identification of precursor cells that give rise to mature…”
Get full text

Functional Antibody Lacking a Variable-Region Disulfide Bridge by Rudikoff, Stuart, Pumphrey, Janet G.

“…In 1981, Auffray et al. [Auffray, C., Sikorav, J. L., Ollo, R. & Rougeon, F. (1981) Ann. Immunol. (Inst. Pasteur) 132D, 77-88] reported a partial cDNA sequence…”
Get full text

Insulin-like growth factor I is a dual effector of multiple myeloma cell growth by Ge, Nie-Lin, Rudikoff, Stuart

“…Multiple myeloma (MM) is an invariably fatal disease that accounts for approximately 1% to 2% of all human cancers. Surprisingly little is known about the…”
Get full text

Monoclonal antibodies to DNA and RNA from NZB/NZW F1 mice: antigenic specificities and NH2 terminal amino acid sequences by Eilat, D, Hochberg, M, Pumphrey, J, Rudikoff, S

“…Two anti-DNA hybridoma autoantibodies ( A52 , D42 ) were prepared by fusing spleen cells from unimmunized NZB/NZW F1 female mice with BALB/c myeloma cells. The…”
Get full text

Purification and properties of Gal repressor:pL-galR fusion in pKC31 plasmid vector by Majumdar, A., Rudikoff, S., Adhya, S.

“…The galR gene, which encodes the Gal repressor protein in Escherichia coli, has been fused to the strong pL promoter of bacteriophage lambda in plasmid pKC31…”
Get full text

In vivo induction of IL-6 by administration of exogenous cytokines and detection of de novo serum levels of IL-6 in tumor-bearing mice by McIntosh, JK, Jablons, DM, Mule, JJ, Nordan, RP, Rudikoff, S, Lotze, MT, Rosenberg, SA

“…We investigated the capacity of several recombinant cytokines to induce IL-6 in vivo in both normal and tumor-bearing (TB) mice. Intravenous administration of…”
Get full text

Somatic Diversification of Immunoglobulins by Rudikoff, Stuart, Pawlita, Michael, Pumphrey, Janet, Heller, Mary

“…A series of three IgM, κ monoclonal antibodies arising from a fusion of BALB/c spleen cells from mice immunized with β -(1,6)-galactan-containing antigens have…”
Get full text

T cell derived IL-6 is differentially required for antigen-specific antibody secretion by primary and secondary B cells by Hilbert, DM, Cancro, MP, Scherle, PA, Nordan, RP, Van Snick, J, Gerhard, W, Rudikoff, S

“…IL-6 (formerly PCTGF, HP-1, BSF-2, HGF, IFN-beta 2, 26 kDa) is a recently defined lymphokine demonstrating activity on multiple cell types, including…”
Get full text

Wnt signaling in B-cell neoplasia by QIANG, Ya-Wei, ENDO, Yoshimi, RUBIN, Jeffrey S, RUDIKOFF, Stuart

“…Wnts comprise a family of secreted proteins that interact with receptors consisting of a Frizzled (Fz) family member alone or complexed with LDL…”
Get full text