Search Results - "Rudewicz, Justine"

New insights into the molecular genetics of recurrent malignant gliomas by Han, Mingzhi, Rudewicz, Justine

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Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis by Guyon, Joris, Fernandez‐Moncada, Ignacio, Larrieu, Claire M, Bouchez, Cyrielle L, Pagano Zottola, Antonio C, Galvis, Johanna, Chouleur, Tiffanie, Burban, Audrey, Joseph, Kevin, Ravi, Vidhya M, Espedal, Heidi, Røsland, Gro Vatne, Daher, Boutaina, Barre, Aurélien, Dartigues, Benjamin, Karkar, Slim, Rudewicz, Justine, Romero‐Garmendia, Irati, Klink, Barbara, Grützmann, Konrad, Derieppe, Marie‐Alix, Molinié, Thibaut, Obad, Nina, Léon, Céline, Seano, Giorgio, Miletic, Hrvoje, Heiland, Dieter Henrik, Marsicano, Giovanni, Nikolski, Macha, Bjerkvig, Rolf, Bikfalvi, Andreas, Daubon, Thomas

“…Lactate is a central metabolite in brain physiology but also contributes to tumor development. Glioblastoma (GB) is the most common and malignant primary brain…”
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Experimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression by Cooley, Lindsay S, Rudewicz, Justine, Souleyreau, Wilfried, Emanuelli, Andrea, Alvarez-Arenas, Arturo, Clarke, Kim, Falciani, Francesco, Dufies, Maeva, Lambrechts, Diether, Modave, Elodie, Chalopin-Fillot, Domitille, Pineau, Raphael, Ambrosetti, Damien, Bernhard, Jean-Christophe, Ravaud, Alain, Négrier, Sylvie, Ferrero, Jean-Marc, Pagès, Gilles, Benzekry, Sebastien, Nikolski, Macha, Bikfalvi, Andreas

“…Renal Cell Carcinoma (RCC) is difficult to treat with 5-year survival rate of 10% in metastatic patients. Main reasons of therapy failure are lack of validated…”
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MICADo - Looking for Mutations in Targeted PacBio Cancer Data: An Alignment-Free Method by Rudewicz, Justine, Soueidan, Hayssam, Uricaru, Raluca, Bonnefoi, Hervé, Iggo, Richard, Bergh, Jonas, Nikolski, Macha

“…Targeted sequencing is commonly used in clinical application of NGS technology since it enables generation of sufficient sequencing depth in the targeted genes…”
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SLIT2/ROBO signaling in tumor-associated microglia and macrophages drives glioblastoma immunosuppression and vascular dysmorphia by Geraldo, Luiz H, Xu, Yunling, Jacob, Laurent, Pibouin-Fragner, Laurence, Rao, Rohit, Maissa, Nawal, Verreault, Maïté, Lemaire, Nolwenn, Knosp, Camille, Lesaffre, Corinne, Daubon, Thomas, Dejaegher, Joost, Solie, Lien, Rudewicz, Justine, Viel, Thomas, Tavitian, Bertrand, De Vleeschouwer, Steven, Sanson, Marc, Bikfalvi, Andreas, Idbaih, Ahmed, Lu, Q Richard, Lima, Flavia Rs, Thomas, Jean-Leon, Eichmann, Anne, Mathivet, Thomas

“…SLIT2 is a secreted polypeptide that guides migration of cells expressing Roundabout 1 and 2 (ROBO1 and ROBO2) receptors. Herein, we investigated SLIT2/ROBO…”
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A community effort to create standards for evaluating tumor subclonal reconstruction by Salcedo, Adriana, Tarabichi, Maxime, Espiritu, Shadrielle Melijah G., Deshwar, Amit G., David, Matei, Wilson, Nathan M., Dentro, Stefan, Wintersinger, Jeff A., Liu, Lydia Y., Ko, Minjeong, Sivanandan, Srinivasan, Zhang, Hongjiu, Zhu, Kaiyi, Ou Yang, Tai-Hsien, Chilton, John M., Buchanan, Alex, Lalansingh, Christopher M., P’ng, Christine, Anghel, Catalina V., Umar, Imaad, Lo, Bryan, Zou, William, Simpson, Jared T., Stuart, Joshua M., Anastassiou, Dimitris, Guan, Yuanfang, Ewing, Adam D., Ellrott, Kyle, Wedge, David C., Morris, Quaid, Van Loo, Peter, Boutros, Paul C.

“…Tumor DNA sequencing data can be interpreted by computational methods that analyze genomic heterogeneity to infer evolutionary dynamics. A growing number of…”
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TGF-β promotes microtube formation in glioblastoma through thrombospondin 1 by Joseph, Justin V, Magaut, Capucine R, Storevik, Simon, Geraldo, Luiz H, Mathivet, Thomas, Latif, Md Abdul, Rudewicz, Justine, Guyon, Joris, Gambaretti, Matteo, Haukas, Frida, Trones, Amalie, Rømo Ystaas, Lars A, Hossain, Jubayer A, Ninzima, Sandra, Cuvellier, Sylvain, Zhou, Wenjing, Tomar, Tushar, Klink, Barbara, Rane, Lalit, Irving, Bronwyn K, Marrison, Joanne, O’Toole, Peter, Wurdak, Heiko, Wang, Jian, Di, Zhang, Birkeland, Even, Berven, Frode S, Winkler, Frank, Kruyt, Frank A E, Bikfalvi, Andreas, Bjerkvig, Rolf, Daubon, Thomas, Miletic, Hrvoje

“…Abstract Background Microtubes (MTs), cytoplasmic extensions of glioma cells, are important cell communication structures promoting invasion and treatment…”
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SLIT2/ROBO signaling in tumor-associated microglia and macrophages drives glioblastoma immunosuppression and vascular dysmorphia by Geraldo, Luiz H, Xu, Yunling, Jacob, Laurent, Pibouin-Fragner, Laurence, Rao, Rohit, Maissa, Nawal, Verreault, Marté, Lemaire, Nolwenn, Knosp, Camille, Lesaffre, Corinne, Daubon, Thomas, Dejaegher, Joost, Solie, Lien, Rudewicz, Justine, Viel, Thomas, Tavitian, Bertrand, De Vleeschouwer, Steven, Sanson, Marc, Bikfalvi, Andreas, Idbaih, Ahmed, Lu, Q Richard, Lima, Flavia R S, Thomas, Jean-Leon, Eichmann, Anne, Mathivet, Thomas

“…SLIT2 is a secreted polypeptide that guides migration of cells expressing Roundabout 1 and 2 (ROBO1 and ROBO2) receptors. Herein, we investigated SLIT2/ROBO…”
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Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis by Guyon, Joris, Fernandez-Moncada, Ignacio, Larrieu, Claire, Bouchez, Cyrielle, Pagano Zottola, Antonio, Galvis, Johanna, Chouleur, Tiffanie, Burban, Audrey, Joseph, Kevin, Ravi, Vidhya, Espedal, Heidi, Røsland, Gro Vatne, Daher, Boutaina, Barre, Aurélien, Dartigues, Benjamin, Karkar, Slim, Rudewicz, Justine, Romero-Garmendia, Irati, Klink, Barbara, Grützmann, Konrad, Derieppe, Marie‐alix, Molinié, Thibaut, Obad, Nina, Léon, Céline, Seano, Giorgio, Miletic, Hrvoje, Heiland, Dieter Henrik, Marsicano, Giovanni, Nikolski, Macha, Bjerkvig, Rolf, Bikfalvi, Andreas, Daubon, Thomas

“…Abstract Lactate is a central metabolite in brain physiology but also contributes to tumor development. Glioblastoma (GB) is the most common and malignant…”
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Clinical and genomic analysis of a randomised phase II study evaluating anastrozole and fulvestrant in postmenopausal patients treated for large operable or locally advanced hormone-receptor-positive breast cancer by Quenel-Tueux, Nathalie, Debled, Marc, Rudewicz, Justine, MacGrogan, Gaetan, Pulido, Marina, Mauriac, Louis, Dalenc, Florence, Bachelot, Thomas, Lortal, Barbara, Breton-Callu, Christelle, Madranges, Nicolas, de Lara, Christine Tunon, Fournier, Marion, Bonnefoi, Hervé, Soueidan, Hayssam, Nikolski, Macha, Gros, Audrey, Daly, Catherine, Wood, Henry, Rabbitts, Pamela, Iggo, Richard

“…Background: The aim of this study was to assess the efficacy of neoadjuvant anastrozole and fulvestrant treatment of large operable or locally advanced…”
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The hexosamine pathway and coat complex II promote malignant adaptation to nutrient scarcity by Dragic, Helena, Barthelaix, Audrey, Duret, Cédric, Le Goupil, Simon, Laprade, Hadrien, Martin, Sophie, Brugière, Sabine, Couté, Yohann, Machon, Christelle, Guitton, Jerome, Rudewicz, Justine, Hofman, Paul, Lebecque, Serge, Chaveroux, Cedric, Ferraro-Peyret, Carole, Renno, Toufic, Manié, Serge N

“…The glucose-requiring hexosamine biosynthetic pathway (HBP), which produces UDP-N-acetylglucosamine for glycosylation reactions, promotes lung adenocarcinoma…”
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Validation of a yeast functional assay for p53 mutations using clonal sequencing by Iggo, Richard, Rudewicz, Justine, Monceau, Elodie, Sevenet, Nicolas, Bergh, Jonas, Sjoblom, Tobias, Bonnefoi, Hervé

“…We have previously tested biopsies from 1469 breast tumours with a p53 functional assay in the context of a prospective clinical trial (EORTC 10994/BIG 1–00)…”
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OTME-14. TGF-beta signaling in microtube formation of glioblastoma by Storevik, Simon, Joseph, Justin, Magaut, Capucine, Henrique, Luiz, Mathivet, Thomas, Latif, Md Abdul, Rudewicz, Justine, Guyon, Joris, Gambaretti, Matteo, Haukås, Frida, Trones, Amalie, Ystaas, Lars Andreas Rømo, Hossain, Jubayer, Ninzima, Sandra, Zhou, Wenjing, Tomar, Tushar, Winkler, Frank, Kruyt, Frank, Bikfalvi, Andreas, Bjerkvig, Rolf, Daubon, Thomas, Miletic, Hrvoje

“…Abstract Microtubes (MTs) are cytoplasmic extensions of glioma cells serving as important cell communication structures while also promoting invasion and…”
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The invasive proteome of glioblastoma revealed by laser-capture microdissection by Daubon, Thomas, Guyon, Joris, Raymond, Anne-Aurélie, Dartigues, Benjamin, Rudewicz, Justine, Ezzoukhry, Zakaria, Dupuy, Jean-William, Herbert, John M J, Saltel, Frédéric, Bjerkvig, Rolf, Nikolski, Macha, Bikfalvi, Andreas

“…Glioblastomas are heterogeneous tumors composed of a necrotic and tumor core and an invasive periphery. Here, we performed a proteomics analysis of…”
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Antioxydation And Cell Migration Genes Are Identified as Potential Therapeutic Targets in Basal-Like and BRCA1 Mutated Breast Cancer Cell Lines by Privat, Maud, Rudewicz, Justine, Sonnier, Nicolas, Tamisier, Christelle, Ponelle-Chachuat, Flora, Bignon, Yves-Jean

“…Basal-like breast cancers are among the most aggressive cancers and effective targeted therapies are still missing. In order to identify new therapeutic…”
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