Search Results - "Ruddy, Shaun"

Modulation of C3b Hemolytic Activity by a Plasma Protein Distinct from C3b Inactivator by Whaley, Keith, Ruddy, Shaun

“…A human plasma protein binds to cell-bound C3b, the major cleavage product of the third component of complement. Consequent upon this binding, C3b no longer…”
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Association of activated properdin with complexes of properdin with C3 by Whiteman, LY, Purkall, DB, Ruddy, S

“…An ELISA using antibody to properdin (P), followed by antibody to C3 to detect complexes of P with C3 (P-C3), detected low levels of P-C3 complexes in human…”
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Formation of a hemolytically active cellular intermediate by the interaction between properdin factors B and D and the activated third component of complement by Fearon, D T, Austen, K F, Ruddy, S

“…The present studies demonstrate that the factor B-dependent C3 convertase can be affixed to an erythrocyte by use of an intermediate bearing C3b and that this…”
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Properdin factor D: characterization of its active site and isolation of the precursor form by Fearon, D T, Austen, K F, Ruddy, S

“…The activity of properdin factor D was measured by the generation of the hemolytically active cellular intermediate, EAC43B(D), bearing the C3b-dependent…”
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C3b Inactivator of Man by Ruddy, Shaun, Austen, K. Frank

“…Abstract C3b inactivator (C3bINA), a normal serum protein that destroys the ability of cells bearing C3b to participate in immune adherence, to undergo…”
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C3 Inactivator of Man by Ruddy, Shaun, Austen, K. Frank

“…Summary C3 Inactivator (C3INA) purified from human serum has been measured by its ability to block the reactivity of the cellular intermediate EAC143 in immune…”
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Elevated plasma C3 anaphylatoxin levels in rheumatoid arthritis patients by Moxley, G, Ruddy, S

“…Because synovial fluid levels of the C3 anaphylatoxins, C3a and C3a desArg, are more than 7 times higher in patients with rheumatoid arthritis (RA) than in…”
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Neutrophil Chemotaxis and Superoxide Production Are Induced by Cross-linking FcγRII Receptors by Scott-Zaki, Patricia, Purkall, Donald, Ruddy, Shaun

“…Neutrophils express two types of receptor for the Fc region of IgG, FcγRII and FcγRIIIB. Via these receptors, neutrophils bind IgG complexes that contain more…”
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Rheumatic diseases and inherited complement deficiencies by Ruddy, S

“…Deficiencies of individual complement proteins may be accompanied by SLE or related syndromes. Deficiencies of the classic activation pathway are often…”
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Hemolytic assay of the ninth complement component: elevation and depletion in rheumatic diseases by Ruddy, S, Everson, L K, Schur, P H, Austen, K F

“…An effective molecule titration for the ninth component of complement in the biologic fluids of man was developed using EAC1-8 cells produced by treating EAC14…”
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Chimpanzee-associated viral hepatitis in 1963 by Ruddy, S J, Mosley, J W, Held, J R

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An Epidemic of Clam-Associated Hepatitis by Ruddy, Shaun J, Johnson, Ronald F, Mosley, James W, Atwater, John B, Rossetti, Michael A, Hart, James C

“…During a 32-week period from November 1963 through June 1964, an epidemic of 123 cases of viral hepatitis following ingestion of raw clams occurred in…”
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Effect of Allotype on Activation of Neutrophils by FcγRIIIB Cross-Linking by Scott-Zaki, Patricia, Purkall, Donald, Ruddy, Shaun

“…Human neutrophils constitutively synthesize two receptors for the constant region of IgG, FcγRII, and FcγRIIIB. Fluo-3-loaded neutrophils were treated with…”
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Successful cyclophosphamide treatment of cryoglobulinemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection by Quigg, R J, Brathwaite, M, Gardner, D F, Gretch, D R, Ruddy, S

“…A 54-year-old man with cryoglobulinemia and chronic hepatitis C infection presented with progressive renal insufficiency caused by membranoproliferative…”
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Myelinated dorsal root ganglion cultures activate both the alternative and classical pathways of complement by Scott-Zaki, Patricia, Purkall, Donald, Bigbee, John, Ruddy, Shaun, Yu, Robert K

“…We used rat myelinated dorsal root ganglion (MDRG) cultures to study antibody and complement-mediated mechanisms of peripheral demyelinating diseases. Heat…”
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Covalent linkage of C3 to properdin during complement activation by Whiteman, L Y, Purkall, D B, Ruddy, S

“…Activation of the alternative complement pathway of serum produces complexes of properdin (P) and C3 as measured in a double antibody enzyme-linked…”
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Conjoint versus separate boards by Shearer, William T., Ruddy, Shaun G., Anderson, John A.

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Effects of thrombospondin purified by heparin affinity or ion-exchange chromatography on the alternative complement pathway by Scott, Patricia E, Purkall, Donald B, Ruddy, Shaun

“…Thrombospondin (TSP), a platelet glycoprotein, was purified from platelet supernatants applied sequentially to Sepharose 4B and heparin-agarose affinity…”
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Conjoint versus separate boards by Shearer, William T., Ruddy, Shaun G., Anderson, John A.

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The American College of Rheumatology as a "professional" society: an oxymoron? by Ruddy, S

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