Search Results - "Ruda, Alessandro"

PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides by Rush, Jeffrey S., Parajuli, Prakash, Ruda, Alessandro, Li, Jian, Pohane, Amol Arunrao, Zamakhaeva, Svetlana, Rahman, Mohammad M., Chang, Jennifer C., Gogos, Artemis, Kenner, Cameron W., Lambeau, Gérard, Federle, Michael J., Korotkov, Konstantin V., Widmalm, Göran, Korotkova, Natalia

“…The cell wall of the human bacterial pathogen Group A Streptococcus (GAS) consists of peptidoglycan decorated with the Lancefield group A carbohydrate (GAC)…”
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An OregonGreen488-labelled d-amino acid for visualizing peptidoglycan by super-resolution STED nanoscopy by Söderström, Bill, Ruda, Alessandro, Widmalm, Göran, Daley, Daniel O

“…Fluorescent d-amino acids (FDAAs) are molecular probes that are widely used for labelling the peptidoglycan layer of bacteria. When added to growing cells they…”
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Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview by Riu, Federico, Ruda, Alessandro, Ibba, Roberta, Sestito, Simona, Lupinu, Ilenia, Piras, Sandra, Widmalm, Göran, Carta, Antonio

“…Certain bacteria constitute a threat to humans due to their ability to escape host defenses as they easily develop drug resistance. Bacteria are classified…”
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Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides by Edgar, Rebecca J., van Hensbergen, Vincent P., Ruda, Alessandro, Turner, Andrew G., Deng, Pan, Le Breton, Yoann, El-Sayed, Najib M., Belew, Ashton T., McIver, Kevin S., McEwan, Alastair G., Morris, Andrew J., Lambeau, Gérard, Walker, Mark J., Rush, Jeffrey S., Korotkov, Konstantin V., Widmalm, Göran, van Sorge, Nina M., Korotkova, Natalia

“…Cell wall glycopolymers on the surface of Gram-positive bacteria are fundamental to bacterial physiology and infection biology. Here we identify gacH , a gene…”
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A Lead-Based Fragment Library Screening of the Glycosyltransferase WaaG from Escherichia coli by Riu, Federico, Ruda, Alessandro, Engström, Olof, Muheim, Claudio, Mobarak, Hani, Ståhle, Jonas, Kosma, Paul, Carta, Antonio, Daley, Daniel O, Widmalm, Göran

“…Glucosyl transferase I (WaaG) in catalyzes the transfer of an α-d-glucosyl group to the inner core of the lipopolysaccharide (LPS) and plays an important role…”
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O‑Methylation in Carbohydrates: An NMR and MD Simulation Study with Application to Methylcellulose by Ruda, Alessandro, Widmalm, Göran, Wohlert, Jakob

“…Methylated carbohydrates are important from both biological and technical perspectives. Specifically, methylcellulose is an interesting cellulose derivative…”
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Nonreducing Sugar Scaffold Enables the Development of Immunomodulatory TLR4‐specific LPS Mimetics with Picomolar Potency by Strobl, Sebastian, Zucchetta, Daniele, Vašíček, Tomáš, Monti, Alessandro, Ruda, Alessandro, Widmalm, Göran, Heine, Holger, Zamyatina, Alla

“…Innate immune defense mechanisms against infection and cancer encompass the modulation of pattern recognition receptor (PRR)‐mediated inflammation, including…”
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A detailed picture of a protein–carbohydrate hydrogen-bonding network revealed by NMR and MD simulations by Nestor, Gustav, Ruda, Alessandro, Anderson, Taigh, Oscarson, Stefan, Widmalm, Göran, Gronenborn, Angela M

“…Abstract Cyanovirin-N (CV-N) is a cyanobacterial lectin with antiviral activity towards HIV and several other viruses. Here, we identify mannoside hydroxyl…”
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Complete 1H and 13C NMR chemical shift assignments of mono-to tetrasaccharides as basis for NMR chemical shift predictions of oligo- and polysaccharides using the computer program CASPER by Furevi, Axel, Ruda, Alessandro, Angles d’Ortoli, Thibault, Mobarak, Hani, Ståhle, Jonas, Hamark, Christoffer, Fontana, Carolina, Engström, Olof, Apostolica, Patricia, Widmalm, Göran

“…Carbohydrate structure can be elucidated or confirmed by using NMR spectroscopy as the prime technique. Prediction of 1H and 13C NMR chemical shifts by…”
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Glycosidic α-linked mannopyranose disaccharides: an NMR spectroscopy and molecular dynamics simulation study employing additive and Drude polarizable force fields by Ruda, Alessandro, Aytenfisu, Asaminew H, Angles d'Ortoli, Thibault, MacKerell, Jr, Alexander D, Widmalm, Göran

“…D-Mannose is a structural component in N-linked glycoproteins from viruses and mammals as well as in polysaccharides from fungi and bacteria. Structural…”
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Glycan Stability and Flexibility: Thermodynamic and Kinetic Characterization of Nonconventional Hydrogen Bonding in Lewis Antigens by Kwon, Jeahoo, Ruda, Alessandro, Azurmendi, Hugo F., Zarb, Jasmin, Battistel, Marcos D., Liao, Liang, Asnani, Ari, Auzanneau, France-Isabelle, Widmalm, Göran, Freedberg, Darón I.

“…We provide evidence for CH-based nonconventional hydrogen bonds (H-bonds) for 10 Lewis antigens and two of their rhamnose analogues. We also characterize the…”
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Nonreducing Sugar Scaffold Enables the Development of Immunomodulatory TLR4‐specific LPS Mimetics with Picomolar Potency by Strobl, Sebastian, Zucchetta, Daniele, Vašíček, Tomáš, Monti, Alessandro, Ruda, Alessandro, Widmalm, Göran, Heine, Holger, Zamyatina, Alla

“…Innate immune defense mechanisms against infection and cancer encompass the modulation of pattern recognition receptor (PRR)‐mediated inflammation, including…”
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Complete 1 H and 13 C NMR chemical shift assignments of mono-to tetrasaccharides as basis for NMR chemical shift predictions of oligo- and polysaccharides using the computer program CASPER by Furevi, Axel, Ruda, Alessandro, Angles d'Ortoli, Thibault, Mobarak, Hani, Ståhle, Jonas, Hamark, Christoffer, Fontana, Carolina, Engström, Olof, Apostolica, Patricia, Widmalm, Göran

“…Carbohydrate structure can be elucidated or confirmed by using NMR spectroscopy as the prime technique. Prediction of H and C NMR chemical shifts by…”
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PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides by Rush, Jeffrey, Parajuli, Prakash, Ruda, Alessandro, Li, Jian, Pohane, Amol, Zamakhaeva, Svetlana, Rahman, Mohammad, Chang, Jennifer, Gogos, Artemis, Kenner, Cameron, Lambeau, Gérard, Federle, Michael, Korotkov, Konstantin, Widmalm, Göran, Korotkova, Natalia

“…Abstract The cell wall of the human bacterial pathogen Group A Streptococcus (GAS) consists of peptidoglycan decorated with the Lancefield group A carbohydrate…”
Get full text