Search Results - "Ruby, Norman F."

Suppression of Circadian Timing and Its Impact on the Hippocampus by Ruby, Norman F

“…In this article, I describe the development of the disruptive phase shift (DPS) protocol and its utility for studying how circadian dysfunction impacts memory…”
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Dysrhythmia in the suprachiasmatic nucleus inhibits memory processing by Fernandez, Fabian, Lu, Derek, Ha, Phong, Costacurta, Patricia, Chavez, Renee, Heller, H. Craig, Ruby, Norman F.

“…Chronic circadian dysfunction impairs declarative memory in humans but has little effect in common rodent models of arrhythmia caused by clock gene knockouts…”
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Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice by Tsai, Jessica W, Hannibal, Jens, Hagiwara, Grace, Colas, Damien, Ruppert, Elisabeth, Ruby, Norman F, Heller, H Craig, Franken, Paul, Bourgin, Patrice

“…Light influences sleep and alertness either indirectly through a well-characterized circadian pathway or directly through yet poorly understood mechanisms…”
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Development of Circadian Sleep Regulation in the Rat: A Longitudinal Study Under Constant Conditions by Frank, Marcos G., Ruby, Norman F., Heller, Horace Craig, Franken, Paul

“…Abstract Study Objectives: To better understand the development of sleep, we characterized the development of circadian rhythms in sleep and wakefulness in the…”
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Spatial memory and long-term object recognition are impaired by circadian arrhythmia and restored by the GABAAAntagonist pentylenetetrazole by Ruby, Norman F, Fernandez, Fabian, Garrett, Alex, Klima, Jessy, Zhang, Pei, Sapolsky, Robert, Heller, H Craig

“…Performance on many memory tests varies across the day and is severely impaired by disruptions in circadian timing. We developed a noninvasive method to…”
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Millisecond Flashes of Light Phase Delay the Human Circadian Clock during Sleep by Zeitzer, Jamie M., Fisicaro, Ryan A., Ruby, Norman F., Heller, H. Craig

“…The human circadian timing system is most sensitive to the phase-shifting effects of light during the biological nighttime, a time at which humans are most…”
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Response of the human circadian system to millisecond flashes of light by Zeitzer, Jamie M, Ruby, Norman F, Fisicaro, Ryan A, Heller, H Craig

“…Ocular light sensitivity is the primary mechanism by which the central circadian clock, located in the suprachiasmatic nucleus (SCN), remains synchronized with…”
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BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output by Meredith, Andrea L, Wiler, Steven W, Miller, Brooke H, Takahashi, Joseph S, Fodor, Anthony A, Ruby, Norman F, Aldrich, Richard W

“…Spontaneous action potentials in the suprachiasmatic nucleus (SCN) are necessary for normal circadian timing of behavior in mammals. The SCN exhibits a daily…”
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Reversible Suppression of Fear Memory Recall by Transient Circadian Arrhythmia by Steiger, Athreya, Farfan, Julia, Fisher, Nathan, Heller, H Craig, Fernandez, Fabian-Xosé, Ruby, Norman F

“…We tested the hypothesis that a temporary period of circadian arrhythmia would transiently impair recall of an aversive memory in Siberian hamsters ( ). Unlike…”
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Role of Melanopsin in Circadian Responses to Light by Ruby, Norman F., Brennan, Thomas J., Xie, Xinmin, Cao, Vinh, Franken, Paul, Heller, H. Craig, O'Hara, Bruce F.

“…Melanopsin has been proposed as an important photoreceptive molecule for the mammalian circadian system. Its importance in this role was tested in melanopsin…”
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Scheduled feeding restores memory and modulates c-Fos expression in the suprachiasmatic nucleus and septohippocampal complex by Ruby, Norman F., Fisher, Nathan, Patton, Danica F., Paul, Matthew J., Fernandez, Fabian, Heller, H. Craig

“…Disruptions in circadian timing impair spatial memory in humans and rodents. Circadian-arrhythmic Siberian hamsters ( Phodopus sungorus ) exhibit substantial…”
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Rethinking Temperature Sensitivity of the Suprachiasmatic Nucleus by Ruby, Norman F.

“…A report by Buhr et al. (2010) proposed that the suprachiasmatic nucleus (SCN) is resistant to phase shifts induced by heat pulses and to entrainment by…”
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Loss of Melanopsin Photoreception and Antagonism of the Histamine H3 Receptor by Ciproxifan Inhibit Light-Induced Sleep in Mice by Muindi, Fanuel, Colas, Damien, Ikeme, Jesse, Ruby, Norman F, Heller, H Craig

“…Light has direct effects on sleep and wakefulness causing arousal in diurnal animals and sleep in nocturnal animals. In the present study, we assessed the…”
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Impaired leukocyte trafficking and skin inflammatory responses in hamsters lacking a functional circadian system by Prendergast, Brian J, Cable, Erin J, Patel, Priyesh N, Pyter, Leah M, Onishi, Kenneth G, Stevenson, Tyler J, Ruby, Norman F, Bradley, Sean P

“…Highlight • A circadian clock in the CNS drives rhythms in leukocyte trafficking and the spleen clock; pacemaker amplitude proportionally-enhances immune…”
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Suprachiasmatic lesions restore object recognition in down syndrome model mice by Chuluun, Bayarsaikhan, Pittaras, Elsa, Hong, Hyunseung, Fisher, Nathan, Colas, Damien, Ruby, Norman F., Heller, H. Craig

“…The Ts65Dn mouse is a well-studied model of trisomy 21, Down syndrome. This mouse strain has severe learning disability as measured by several rodent learning…”
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Acute Light Exposure Suppresses Circadian Rhythms in Clock Gene Expression by Grone, Brian P., Chang, Doris, Bourgin, Patrice, Cao, Vinh, Fernald, Russell D., Heller, H. Craig, Ruby, Norman F.

“…Light can induce arrhythmia in circadian systems by several weeks of constant light or by a brief light stimulus given at the transition point of the phase…”
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Loss of Circadian Timing Disrupts Theta Episodes during Object Exploration by Loewke, Adrienne C, Garrett, Alex, Steiger, Athreya, Fisher, Nathan, Heller, H Craig, Colas, Damien, Ruby, Norman F

“…This study examined whether theta oscillations were compromised by the type of circadian disruption that impairs hippocampal-dependent memory processes. In…”
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Sleep and circadian rhythms in mammalian torpor by Heller, H Craig, Ruby, Norman F

“…Sleep and circadian rhythms are the primary determinants of arousal state, and torpor is the most extreme state change that occurs in mammals. The view that…”
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Hibernation: When Good Clocks Go Cold by Ruby, Norman F.

“…Hibernatinganimals have been a successful model system for elucidating fundamental properties of many physiological systems. Over the past 50 years, a diverse…”
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Sleep Deprivation Effects on Growth Factor Expression in Neonatal Rats: A Potential Role for BDNF in the Mediation of Delta Power by Hairston, Ilana S, Peyron, Christelle, Denning, Daniel P, Ruby, Norman F, Flores, Judith, Sapolsky, Robert M, Heller, H. Craig, O'Hara, Bruce F

“…1 Department of Biological Sciences, Stanford University, Stanford, California 94305-5020 2 Centre National de la Recherche Scientifique Unité Mixte de…”
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