Search Results - "Ruby, J. J."
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1
Naked Mole-Rat mortality rates defy gompertzian laws by not increasing with age
Published in eLife (24-01-2018)“…The longest-lived rodent, the naked mole-rat ( , has a reported maximum lifespan of >30 years and exhibits delayed and/or attenuated age-associated…”
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2
Guidelines and definitions for research on epithelial–mesenchymal transition
Published in Nature reviews. Molecular cell biology (01-06-2020)“…Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to…”
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3
Acoel genome reveals the regulatory landscape of whole-body regeneration
Published in Science (American Association for the Advancement of Science) (15-03-2019)“…Whole-body regeneration is accompanied by complex transcriptomic changes, yet the chromatin regulatory landscapes that mediate this dynamic response remain…”
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4
How self-generated thought shapes mood--the relation between mind-wandering and mood depends on the socio-temporal content of thoughts
Published in PloS one (23-10-2013)“…Recent work has highlighted that the generation of thoughts unrelated to the current environment may be both a cause and a consequence of unhappiness. The…”
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Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating
Published in Genetics (Austin) (01-11-2018)“…Human life span is a phenotype that integrates many aspects of health and environment into a single ultimate quantity: the elapsed time between birth and…”
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6
Quenching time-scales of galaxies in the eagle simulations
Published in Monthly notices of the Royal Astronomical Society (11-08-2019)“…ABSTRACT We use the eagle simulations to study the connection between the quenching time-scale, τQ, and the physical mechanisms that transform star-forming…”
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7
Intronic microRNA precursors that bypass Drosha processing
Published in Nature (05-07-2007)“…MicroRNAs (miRNAs) are ∼22-nucleotide endogenous RNAs that often repress the expression of complementary messenger RNAs. In animals, miRNAs derive from…”
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8
Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia
Published in PloS one (07-06-2011)“…Honey bees (Apis mellifera) play a critical role in global food production as pollinators of numerous crops. Recently, honey bee populations in the United…”
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The impact of stellar and AGN feedback on halo-scale baryonic and dark matter accretion in the eagle simulations
Published in Monthly notices of the Royal Astronomical Society (01-10-2020)“…ABSTRACT We use the eagle suite of hydrodynamical simulations to analyse accretion rates (and the breakdown of their constituent channels) on to haloes over…”
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10
Revealing the physical properties of gas accreting to haloes in the EAGLE simulations
Published in Monthly notices of the Royal Astronomical Society (01-07-2021)“…ABSTRACT The inflow of cosmological gas on to haloes, while challenging to directly observe and quantify, plays a fundamental role in the baryon cycle of…”
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Transcriptome Sequencing Demonstrates that Human Papillomavirus Is Not Active in Cutaneous Squamous Cell Carcinoma
Published in Journal of investigative dermatology (01-08-2011)“…β-Human papillomavirus (β-HPV) DNA is present in some cutaneous squamous cell carcinomas (cuSCCs), but no mechanism of carcinogenesis has been determined. We…”
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12
A novel rhabdovirus associated with acute hemorrhagic fever in central Africa
Published in PLoS pathogens (01-09-2012)“…Deep sequencing was used to discover a novel rhabdovirus (Bas-Congo virus, or BASV) associated with a 2009 outbreak of 3 human cases of acute hemorrhagic fever…”
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13
Interferon-stimulated GTPases in autoimmune and inflammatory diseases: promising role for the guanylate-binding protein (GBP) family
Published in Rheumatology (Oxford, England) (01-02-2021)“…Abstract Human IFNs are secreted cytokines shown to stimulate the expression of over one thousand genes. These IFN-inducible genes primarily encode four major…”
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14
Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs
Published in Genes & development (15-10-2008)“…Canonical microRNAs (miRNAs) require two processing steps: the first by the Microprocessor, a complex of DGCR8 and Drosha, and the second by a complex of TRBP…”
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15
Energy Flow in Thin Shell Implosions and Explosions
Published in Physical review letters (18-11-2020)“…Energy flow and balance in convergent systems beyond petapascal energy densities controls the fate of late-stage stars and the potential for controlling…”
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16
Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution
Published in Genome biology (30-01-2013)“…BACKGROUND: Centromeres are essential for chromosome segregation, yet their DNA sequences evolve rapidly. In most animals and plants that have been studied,…”
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17
Formation, regulation and evolution of Caenorhabditis elegans 3'UTRs
Published in Nature (London) (06-01-2011)“…Post-transcriptional gene regulation frequently occurs through elements in mRNA 3' untranslated regions (UTRs). Although crucial roles for 3'UTR-mediated gene…”
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The diverse nature and formation paths of slow rotator galaxies in the eagle simulations
Published in Monthly notices of the Royal Astronomical Society (01-01-2022)“…ABSTRACT We use a sample of z = 0 galaxies visually classified as slow rotators (SRs) in the eagle hydrodynamical simulations to explore the effect of galaxy…”
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PRICE: software for the targeted assembly of components of (Meta) genomic sequence data
Published in G3 : genes - genomes - genetics (01-05-2013)“…Low-cost DNA sequencing technologies have expanded the role for direct nucleic acid sequencing in the analysis of genomes, transcriptomes, and the metagenomes…”
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An orbital perspective on the starvation, stripping, and quenching of satellite galaxies in the eagle simulations
Published in Monthly notices of the Royal Astronomical Society (14-09-2022)“…ABSTRACT Using the eagle (Evolution and Assembly of GaLaxies and their Environments) suite of simulations, we demonstrate that both cold gas stripping and…”
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