Search Results - "Ruble, Gaye R."
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The effect of commonly used vehicles on canine hematology and clinical chemistry values
Published in Journal of the American Association for Laboratory Animal Science (01-01-2006)“…Drug metabolism and pharmacokinetic (DMPK) studies are an important phase in drug discovery research. Compounds are administered via the intravascular or…”
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Evaluation of Injectable Anesthetics for Major Surgical Procedures in Guinea Pigs
Published in Contemporary topics in laboratory animal science (01-07-1998)“…Anesthetizing guinea pigs is difficult with varying outcomes. The primary purpose of the study reported here was to evaluate six injectable anesthetic regimens…”
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Effects of Buprenorphine on Immunogenicity and Protective Efficacy in the Guinea Pig Keratoconjunctivitis Model (Sereny Test)
Published in Comparative medicine (01-06-2001)“…Shigellosis is a disease of global proportions, with an estimated 164.7 million episodes annually throughout the world as well as an estimated 1.1 million…”
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Evaluation of surrogate markers of impending death in the galactosamine-sensitized murine model of bacterial endotoxemia
Published in Laboratory animal science (Chicago) (01-10-1999)“…When evaluating vaccines for efficacy against gram-negative endotoxemia, the challenge has historically required death of a large percentage of test subjects…”
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Evaluation of objects and food for environmental enrichment of NZW rabbits
Published in Contemporary topics in laboratory animal science (01-01-2001)“…The Guide for the Care and Use of Laboratory Animals states that both structural and social environments should be considered when addressing the husbandry…”
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Comparison of adjuvants with Leishmania antigens in a guinea pig model to induce delayed-type hypersensitivity responses
Published in Laboratory animal science (Chicago) (01-10-1999)“…Guinea pigs have been a traditional model for studies of delayed-type hypersensitivity. They are the natural host of Leishmania enriettii and have been…”
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