Search Results - "Rubis, Blazej"
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Vitamin C as a Modulator of the Response to Cancer Therapy
Published in Molecules (Basel, Switzerland) (28-01-2019)“…Ascorbic acid (vitamin C) has been gaining attention as a potential treatment for human malignancies. Various experimental studies have shown the ability of…”
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2
Human Vault RNAs: Exploring Their Potential Role in Cellular Metabolism
Published in International journal of molecular sciences (01-04-2024)“…Non-coding RNAs have been described as crucial regulators of gene expression and guards of cellular homeostasis. Some recent papers focused on vault RNAs, one…”
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3
The Role of Activation of PI3K/AKT/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas-New Potential Therapeutic Approach-A Systematic Review
Published in International journal of molecular sciences (30-06-2023)“…Pituitary tumors (PT) are mostly benign, although occasionally they demonstrate aggressive behavior, invasion of surrounding tissues, rapid growth, resistance…”
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4
Telomerase Inhibitor TMPyP4 Alters Adhesion and Migration of Breast-Cancer Cells MCF7 and MDA-MB-231
Published in International journal of molecular sciences (30-05-2019)“…Human telomeres were one of the first discovered and characterized sequences forming quadruplex structures. Association of these structures with oncogenic and…”
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5
Pacemaker remote monitoring challenges in pediatric population: Single center long term experience
Published in Kardiologia polska (01-01-2024)“…Remote monitoring (RM) of cardiac implantable electronic devices for adults offers improved treatment efficacy and, consequently, better patient clinical…”
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6
Cytotoxic, analgesic and anti-inflammatory activity of colchicine and its C-10 sulfur containing derivatives
Published in Scientific reports (27-04-2021)“…10-Alkylthiocolchicines have been obtained and characterized by spectroscopic methods and their biological activities as: cytotoxic, anti-inflammatory and…”
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7
miRNA Expression Profiling in Human Breast Cancer Diagnostics and Therapy
Published in Current issues in molecular biology (25-11-2023)“…Breast cancer is one of the most commonly diagnosed cancer types worldwide. Regarding molecular characteristics and classification, it is a heterogeneous…”
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8
Proapoptotic and proautophagic activity of 20-hydroxyecdysone in breast cancer cells in vitro
Published in Chemico-biological interactions (01-06-2021)“…The present study was designed to identify the biological activity of three ecdysones, i.e., 20-hydroxyecdysone (20-HE), ajugasterone C, and polypodine B…”
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9
The combination therapy using tyrosine kinase receptors inhibitors and repurposed drugs to target patient-derived glioblastoma stem cells
Published in Biomedicine & pharmacotherapy (01-07-2024)“…The lesson from many studies investigating the efficacy of targeted therapy in glioblastoma (GBM) showed that a future perspective should be focused on…”
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10
Breast Cancer Stem Cells and Tumor Heterogeneity: Characteristics and Therapeutic Strategies
Published in Cancers (07-07-2024)“…Breast cancer is one of the most frequently detected malignancies worldwide. It is responsible for more than 15% of all death cases caused by cancer in women…”
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11
Alternative Therapies in Transplantology as a Promising Perspective in Medicine
Published in Annals of transplantation (04-06-2024)“…Despite continuous and rapid progress in the transplantation of cells, tissues, and organs, many patients die before receiving them. This is because of an…”
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12
Resveratrol delays replicative senescence of human mesothelial cells via mobilization of antioxidative and DNA repair mechanisms
Published in Free radical biology & medicine (01-06-2012)“…Resveratrol (3,4′,5-trihydroxy-trans-stilbene; RVT) is a natural phytoestrogen known to modulate the rate of senescence in cultured cells. The mechanism by…”
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13
Rosmarinic acid 4′-O-β-glucoside – A compound with prospective medicinal and cosmetological applications - its isolation from callus and root cultures of Eryngium species and biological activity
Published in Industrial crops and products (01-03-2023)“…The goal of the studies was to check if biomass from in vitro cultures of certain Eryngium species could be a source of rosmarinic acid glucoside, which is…”
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14
Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents
Published in Aging cell (01-06-2023)“…Despite the growing interest by researchers into cellular senescence, a hallmark of cellular aging, its role in human skin remains equivocal. The skin is the…”
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15
LEP (−2548G>A LEP) and LEPR (223Gln>Arg, 109Lys>Arg) polymorphisms as breast cancer risk factors in the Polish female population
Published in Molecular biology reports (01-04-2021)“…On a global scale, breast cancer is the most common type of cancer in women, and it is still a growing problem. Therefore, new prognostic or diagnostic markers…”
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Biological Activity of Oleanolic Acid Derivatives HIMOXOL and Br-HIMOLID in Breast Cancer Cells Is Mediated by ER and EGFR
Published in International journal of molecular sciences (01-03-2023)“…Breast cancer is one of the most frequently observed malignancies worldwide and represents a heterogeneous group of cancers. For this reason, it is crucial to…”
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Oleanolic Acid's Semisynthetic Derivatives HIMOXOL and Br-HIMOLID Show Proautophagic Potential and Inhibit Migration of HER2-Positive Breast Cancer Cells In Vitro
Published in International journal of molecular sciences (19-10-2021)“…Approximately 20-30% of the diagnosed breast cancers overexpress the human epidermal growth factor receptor 2 (HER2). This type of cancer is associated with a…”
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18
Serum from patients with chronic obstructive pulmonary disease induces senescence-related phenotype in bronchial epithelial cells
Published in Scientific reports (28-08-2018)“…Chronic obstructive pulmonary disease (COPD) is a risk factor for the development of lung cancer (LC). The mechanism of interplay between both diseases remains…”
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Early Smartphone App-Based Remote Diagnosis of Silent Atrial Fibrillation and Ventricular Fibrillation in a Patient with Cardiac Resynchronization Therapy Defibrillator
Published in Journal of cardiovascular development and disease (01-01-2023)“…Due to distressing statistics concerning cardiovascular diseases, remote monitoring of cardiac implantable electronic devices (CIED) has received a priority…”
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20
The influence of genetic polymorphism of Cyp2c19 isoenzyme on the pharmacokinetics of clopidogrel and its metabolites in patients with cardiovascular diseases
Published in Journal of clinical pharmacology (01-08-2014)“…An extensive investigation on pharmacokinetics of clopidogrel and its metabolites as well as pharmacodynamics of the drug was performed in patients with…”
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