Search Results - "Rubio, L. L."
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Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability
Published in Molecular cell (18-12-2014)“…R-loops, consisting of an RNA-DNA hybrid and displaced single-stranded DNA, are physiological structures that regulate various cellular processes occurring on…”
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The Fanconi Anemia Pathway Protects Genome Integrity from R-loops
Published in PLoS genetics (01-11-2015)“…Co-transcriptional RNA-DNA hybrids (R loops) cause genome instability. To prevent harmful R loop accumulation, cells have evolved specific eukaryotic factors,…”
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3
BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2
Published in Nature (London) (17-07-2014)“…BRCA2, the breast cancer susceptibility gene factor, interacts with TREX-2, a protein complex involved in the biogenesis and export of messenger…”
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Chromospheric Heating due to Cancellation of Quiet Sun Internetwork Fields
Published in The Astrophysical journal (10-04-2018)“…The heating of the solar chromosphere remains one of the most important questions in solar physics. Our current understanding is that small-scale internetwork…”
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THE SOLAR INTERNETWORK. II. FLUX APPEARANCE AND DISAPPEARANCE RATES
Published in The Astrophysical journal (20-03-2016)“…ABSTRACT Small-scale internetwork magnetic fields are important ingredients of the quiet Sun. In this paper we analyze how they appear and disappear on the…”
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Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
Published in The New England journal of medicine (11-02-2021)“…The authors report interim results of the WHO Solidarity trial of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon…”
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FANCD2 Facilitates Replication through Common Fragile Sites
Published in Molecular cell (20-10-2016)“…Common fragile sites (CFSs) are genomic regions that are unstable under conditions of replicative stress. Although the characteristics of CFSs that render them…”
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THE SOLAR INTERNETWORK. I. CONTRIBUTION TO THE NETWORK MAGNETIC FLUX
Published in The Astrophysical journal (10-12-2014)“…The magnetic network (NE) observed on the solar surface harbors a sizable fraction of the total quiet Sun flux. However, its origin and maintenance are not…”
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Histone Mutants Separate R Loop Formation from Genome Instability Induction
Published in Molecular cell (01-06-2017)“…R loops have positive physiological roles, but they can also be deleterious by causing genome instability, and the mechanisms for this are unknown. Here we…”
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The Solar Internetwork. III. Unipolar versus Bipolar Flux Appearance
Published in The Astrophysical journal (01-02-2022)“…Small-scale internetwork (IN) magnetic fields are considered to be the main building blocks of quiet Sun magnetism. For this reason, it is crucial to…”
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CYLD in health and disease
Published in Disease models & mechanisms (01-06-2023)“…CYLD lysine 63 deubiquitinase (CYLD) is a ubiquitin hydrolase with important roles in immunity and cancer. Complete CYLD ablation, truncation and expression of…”
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Emergence of Internetwork Magnetic Fields through the Solar Atmosphere
Published in The Astrophysical journal (01-04-2021)“…Internetwork (IN) magnetic fields are highly dynamic, short-lived magnetic structures that populate the interior of supergranular cells. Since they emerge all…”
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DIFFUSION OF MAGNETIC ELEMENTS IN A SUPERGRANULAR CELL
Published in The Astrophysical journal (20-06-2014)“…Small scale magnetic fields (magnetic elements) are ubiquitous in the solar photosphere. Their interaction can provide energy to the upper atmospheric layers,…”
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A taxonomy for key performance indicators management
Published in Computer standards and interfaces (01-05-2019)“…•We provide a unified taxonomy for KPIs management that gathers any relevant aspect highlighted by the literature.•We rigorously apply a methodology for…”
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Proteomic insights into the effect of Broad bean wilt virus-1 infection in Nicotiana benthamiana plants
Published in European journal of plant pathology (01-05-2024)“…Broad bean wilt virus 1 (BBWV-1, genus Fabavirus , family Secoviridae ) infects many plants species, including important horticultural crops. Since some…”
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WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage
Published in Nature communications (29-06-2022)“…Perturbation in the replication-stress response (RSR) and DNA-damage response (DDR) causes genomic instability. Genomic instability occurs in Wiskott-Aldrich…”
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RNA polymerase II contributes to preventing transcription-mediated replication fork stalls
Published in The EMBO journal (14-01-2015)“…Transcription is a major contributor to genome instability. A main cause of transcription‐associated instability relies on the capacity of transcription to…”
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LATERAL DOWNFLOWS IN SUNSPOT PENUMBRAL FILAMENTS AND THEIR TEMPORAL EVOLUTION
Published in The Astrophysical journal (20-04-2015)“…ABSTRACT We study the temporal evolution of downflows observed at the lateral edges of penumbral filaments in a sunspot located very close to the disk center…”
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SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T‐cell neoplasms
Published in British journal of haematology (01-05-2023)“…Summary Despite the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway being frequently altered in T‐ALL/LBL, no specific…”
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The behaviour of Tenax as food simulant in the migration of polymer additives from food contact materials by means of gas chromatography/mass spectrometry and PARAFAC
Published in Journal of Chromatography A (29-03-2019)“…•Migration of polymer additives from food contact materials into Tenax was studied.•PARAFAC enabled the unequivocal identification in the presence of coeluting…”
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