Search Results - "Rubio, Julio M."
-
1
Regulation of Phagocytosis in Macrophages by Membrane Ethanolamine Plasmalogens
Published in Frontiers in immunology (24-07-2018)“…Macrophages, as professional phagocytes of the immune system, possess the ability to detect and clear invading pathogens and apoptotic cells through…”
Get full text
Journal Article -
2
Group V secreted phospholipase A2 is upregulated by IL-4 in human macrophages and mediates phagocytosis via hydrolysis of ethanolamine phospholipids
Published in The Journal of immunology (1950) (01-04-2015)“…Studies on the heterogeneity and plasticity of macrophage populations led to the identification of two major polarization states: classically activated…”
Get full text
Journal Article -
3
Sequestration of 9-Hydroxystearic Acid in FAHFA (Fatty Acid Esters of Hydroxy Fatty Acids) as a Protective Mechanism for Colon Carcinoma Cells to Avoid Apoptotic Cell Death
Published in Cancers (12-04-2019)“…Hydroxy fatty acids are known to cause cell cycle arrest and apoptosis. The best studied of them, 9-hydroxystearic acid (9-HSA), induces apoptosis in cell…”
Get full text
Journal Article -
4
Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes
Published in Journal of lipid research (01-11-2012)“…Exposure of human peripheral blood monocytes to free arachidonic acid (AA) results in the rapid induction of lipid droplet (LD) formation by these cells. This…”
Get full text
Journal Article -
5
Differential Mobilization of the Phospholipid and Triacylglycerol Pools of Arachidonic Acid in Murine Macrophages
Published in Biomolecules (Basel, Switzerland) (01-12-2022)“…Innate immune cells such as monocytes and macrophages contain high levels of arachidonic acid (AA), part of which can be mobilized during cellular activation…”
Get full text
Journal Article -
6
The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s to Adrenic Acid Mobilization in Murine Macrophages
Published in Biomolecules (Basel, Switzerland) (03-04-2020)“…Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal…”
Get full text
Journal Article -
7
Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A2γ in Phospholipid Remodeling
Published in Cells (Basel, Switzerland) (31-07-2019)“…Availability of free arachidonic acid (AA) constitutes a rate limiting factor for cellular eicosanoid synthesis. AA distributes differentially across membrane…”
Get full text
Journal Article -
8
A phosphatidylinositol species acutely generated by activated macrophages regulates innate immune responses
Published in The Journal of immunology (1950) (15-05-2013)“…Activation of macrophages with stimuli of the innate immune response results in the intense remodeling of arachidonate-containing phospholipids, leading to the…”
Get full text
Journal Article -
9
Choline Glycerophospholipid-Derived Prostaglandins Attenuate TNFα Gene Expression in Macrophages via a cPLA2α/COX-1 Pathway
Published in Cells (Basel, Switzerland) (19-02-2021)“…Macrophages are professional antigen presenting cells with intense phagocytic activity, strategically distributed in tissues and cavities. These cells are…”
Get full text
Journal Article -
10
Phospholipase A2 regulation of lipid droplet formation
Published in Biochimica et biophysica acta (01-12-2014)“…The classical regard of lipid droplets as mere static energy-storage organelles has evolved dramatically. Nowadays these organelles are known to participate in…”
Get full text
Journal Article -
11
The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase [A.sub.2]s to Adrenic Acid Mobilization in Murine Macrophages
Published in Biomolecules (Basel, Switzerland) (01-04-2020)“…Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal…”
Get full text
Journal Article -
12
Phospholipid sources for adrenic acid mobilization in RAW 264.7 macrophages. Comparison with arachidonic acid
Published in Biochimica et biophysica acta (01-11-2012)“…Cells metabolize arachidonic acid (AA) to adrenic acid (AdA) via 2-carbon elongation reactions. Like AA, AdA can be converted into multiple oxygenated…”
Get full text
Journal Article -
13
Choline Glycerophospholipid-Derived Prostaglandins Attenuate TNFα Gene Expression in Macrophages via a cPLA 2 α/COX-1 Pathway
Published in Cells (Basel, Switzerland) (19-02-2021)“…Macrophages are professional antigen presenting cells with intense phagocytic activity, strategically distributed in tissues and cavities. These cells are…”
Get full text
Journal Article -
14
The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A 2 s to Adrenic Acid Mobilization in Murine Macrophages
Published in Biomolecules (Basel, Switzerland) (03-04-2020)“…Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal…”
Get full text
Journal Article -
15
Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A 2 γ in Phospholipid Remodeling
Published in Cells (Basel, Switzerland) (31-07-2019)“…Availability of free arachidonic acid (AA) constitutes a rate limiting factor for cellular eicosanoid synthesis. AA distributes differentially across membrane…”
Get full text
Journal Article