Search Results - "Rubio, Julio M."

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  1. 1

    Regulation of Phagocytosis in Macrophages by Membrane Ethanolamine Plasmalogens by Rubio, Julio M, Astudillo, Alma M, Casas, Javier, Balboa, María A, Balsinde, Jesús

    Published in Frontiers in immunology (24-07-2018)
    “…Macrophages, as professional phagocytes of the immune system, possess the ability to detect and clear invading pathogens and apoptotic cells through…”
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    Journal Article
  2. 2

    Group V secreted phospholipase A2 is upregulated by IL-4 in human macrophages and mediates phagocytosis via hydrolysis of ethanolamine phospholipids by Rubio, Julio M, Rodríguez, Juan P, Gil-de-Gómez, Luis, Guijas, Carlos, Balboa, María A, Balsinde, Jesús

    Published in The Journal of immunology (1950) (01-04-2015)
    “…Studies on the heterogeneity and plasticity of macrophage populations led to the identification of two major polarization states: classically activated…”
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  3. 3

    Sequestration of 9-Hydroxystearic Acid in FAHFA (Fatty Acid Esters of Hydroxy Fatty Acids) as a Protective Mechanism for Colon Carcinoma Cells to Avoid Apoptotic Cell Death by Rodríguez, Juan P, Guijas, Carlos, Astudillo, Alma M, Rubio, Julio M, Balboa, María A, Balsinde, Jesús

    Published in Cancers (12-04-2019)
    “…Hydroxy fatty acids are known to cause cell cycle arrest and apoptosis. The best studied of them, 9-hydroxystearic acid (9-HSA), induces apoptosis in cell…”
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  4. 4

    Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes by Guijas, Carlos, Pérez-Chacón, Gema, Astudillo, Alma M., Rubio, Julio M., Gil-de-Gómez, Luis, Balboa, María A., Balsinde, Jesús

    Published in Journal of lipid research (01-11-2012)
    “…Exposure of human peripheral blood monocytes to free arachidonic acid (AA) results in the rapid induction of lipid droplet (LD) formation by these cells. This…”
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  5. 5

    Differential Mobilization of the Phospholipid and Triacylglycerol Pools of Arachidonic Acid in Murine Macrophages by Bermúdez, Miguel A, Rubio, Julio M, Balboa, María A, Balsinde, Jesús

    Published in Biomolecules (Basel, Switzerland) (01-12-2022)
    “…Innate immune cells such as monocytes and macrophages contain high levels of arachidonic acid (AA), part of which can be mobilized during cellular activation…”
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  6. 6

    The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s to Adrenic Acid Mobilization in Murine Macrophages by Monge, Patricia, Garrido, Alvaro, Rubio, Julio M., Magrioti, Victoria, Kokotos, George, Balboa, María A., Balsinde, Jesús

    Published in Biomolecules (Basel, Switzerland) (03-04-2020)
    “…Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal…”
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  7. 7

    Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A2γ in Phospholipid Remodeling by Lebrero, Patricia, Astudillo, Alma M., Rubio, Julio M., Fernández-Caballero, Lidia, Kokotos, George, Balboa, María A., Balsinde, Jesús

    Published in Cells (Basel, Switzerland) (31-07-2019)
    “…Availability of free arachidonic acid (AA) constitutes a rate limiting factor for cellular eicosanoid synthesis. AA distributes differentially across membrane…”
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  8. 8

    A phosphatidylinositol species acutely generated by activated macrophages regulates innate immune responses by Gil-de-Gómez, Luis, Astudillo, Alma M, Meana, Clara, Rubio, Julio M, Guijas, Carlos, Balboa, María A, Balsinde, Jesús

    Published in The Journal of immunology (1950) (15-05-2013)
    “…Activation of macrophages with stimuli of the innate immune response results in the intense remodeling of arachidonate-containing phospholipids, leading to the…”
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  9. 9

    Choline Glycerophospholipid-Derived Prostaglandins Attenuate TNFα Gene Expression in Macrophages via a cPLA2α/COX-1 Pathway by Astudillo, Alma M., Rodríguez, Juan P., Guijas, Carlos, Rubio, Julio M., Balboa, María A., Balsinde, Jesús

    Published in Cells (Basel, Switzerland) (19-02-2021)
    “…Macrophages are professional antigen presenting cells with intense phagocytic activity, strategically distributed in tissues and cavities. These cells are…”
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    Journal Article
  10. 10

    Phospholipase A2 regulation of lipid droplet formation by Guijas, Carlos, Rodríguez, Juan P., Rubio, Julio M., Balboa, María A., Balsinde, Jesús

    Published in Biochimica et biophysica acta (01-12-2014)
    “…The classical regard of lipid droplets as mere static energy-storage organelles has evolved dramatically. Nowadays these organelles are known to participate in…”
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  11. 11

    The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase [A.sub.2]s to Adrenic Acid Mobilization in Murine Macrophages by Monge, Patricia, Garrido, Alvaro, Rubio, Julio M, Magrioti, Victoria, Kokotos, George, Balboa, Maria A, Balsinde, Jesus

    Published in Biomolecules (Basel, Switzerland) (01-04-2020)
    “…Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal…”
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    Journal Article
  12. 12

    Phospholipid sources for adrenic acid mobilization in RAW 264.7 macrophages. Comparison with arachidonic acid by Guijas, Carlos, Astudillo, Alma M., Gil-de-Gómez, Luis, Rubio, Julio M., Balboa, María A., Balsinde, Jesús

    Published in Biochimica et biophysica acta (01-11-2012)
    “…Cells metabolize arachidonic acid (AA) to adrenic acid (AdA) via 2-carbon elongation reactions. Like AA, AdA can be converted into multiple oxygenated…”
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  13. 13

    Choline Glycerophospholipid-Derived Prostaglandins Attenuate TNFα Gene Expression in Macrophages via a cPLA 2 α/COX-1 Pathway by Astudillo, Alma M, Rodríguez, Juan P, Guijas, Carlos, Rubio, Julio M, Balboa, María A, Balsinde, Jesús

    Published in Cells (Basel, Switzerland) (19-02-2021)
    “…Macrophages are professional antigen presenting cells with intense phagocytic activity, strategically distributed in tissues and cavities. These cells are…”
    Get full text
    Journal Article
  14. 14

    The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A 2 s to Adrenic Acid Mobilization in Murine Macrophages by Monge, Patricia, Garrido, Alvaro, Rubio, Julio M, Magrioti, Victoria, Kokotos, George, Balboa, María A, Balsinde, Jesús

    Published in Biomolecules (Basel, Switzerland) (03-04-2020)
    “…Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal…”
    Get full text
    Journal Article
  15. 15

    Cellular Plasmalogen Content Does Not Influence Arachidonic Acid Levels or Distribution in Macrophages: A Role for Cytosolic Phospholipase A 2 γ in Phospholipid Remodeling by Lebrero, Patricia, Astudillo, Alma M, Rubio, Julio M, Fernández-Caballero, Lidia, Kokotos, George, Balboa, María A, Balsinde, Jesús

    Published in Cells (Basel, Switzerland) (31-07-2019)
    “…Availability of free arachidonic acid (AA) constitutes a rate limiting factor for cellular eicosanoid synthesis. AA distributes differentially across membrane…”
    Get full text
    Journal Article