Search Results - "Rubio, Itziar"
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Molecular mechanism implicated in Pemetrexed-induced apoptosis in human melanoma cells
Published in Molecular cancer (26-04-2012)“…Metastatic melanoma is a lethal skin cancer and its incidence is rising every year. It represents a challenge for oncologist, as the current treatment options…”
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Thymidylate synthase expression determines pemetrexed targets and resistance development in tumour cells
Published in PloS one (13-05-2013)“…Although treatment options for cancer patients are increasing every year, the drug resistance problem remains very present. It is very difficult to find a drug…”
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Concurrent chemoradiation and adjuvant chemotherapy in newly diagnosed glioblastoma multiforme: A retrospective analysis of single center
Published in Journal of clinical oncology (01-06-2023)“…e14053 Background: The standard of care of glioblastoma multiforme (GBM) first line therapy is maximum safe debulking and posterior treatment based in…”
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Glioblastoma in elderly patients: A retrospective analysis of survival and response based on molecular and clinical characteristics—Experience in our centre
Published in Journal of clinical oncology (01-06-2023)“…e14054 Background: Glioblastoma (GBM) is the most lethal and the most common malignant central nervous system tumor in adults. The standard treatment includes…”
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First-line pembrolizumab plus platinum-pemetrexed in metastatic non-small cell lung cancer: Clinical experience in a Spanish tertiary hospital
Published in Journal of clinical oncology (01-06-2023)“…e21142 Background: In the phase III trial KEYNOTE-189 first-line pembrolizumab (pembro) plus platinum-pemetrexed (pem) significantly improved OS and PFS in…”
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The influence of carrying BRCA pathogenic mutations in ovarian cancer and its platinum-sensitivity: 5-year experience of a tertiary center
Published in Journal of clinical oncology (01-06-2022)“…e17572 Background: Platinum-based chemotherapy still remains as the backbone treatment in ovarian cancer (OC) and its homologous tumors (primary peritoneal PP…”
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Final results of a phase II study of bevacizumab, cisplatin and pemetrexed as first-line therapy for patients with advanced non squamous non small cell lung cancer
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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Preoperative chemoradiotherapy (QT-RT) with capecitabine and oxaliplatin (CAPOX) or capecitabine alone (CAP) in patients (PTS) with locally advanced rectal cancer (LARC)
Published in Journal of clinical oncology (20-05-2013)“…Abstract only e14712 Background: Preoperative concomitant QT-RT has shown to improve sphincter preservation and local control in LARC. We analyzed two cohorts…”
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Bevacizumab (BV) plus irinotecan (I) in recurrent glioblastoma multiforme (GBM): A single center experience
Published in Journal of clinical oncology (20-05-2013)“…Abstract only e13000 Background: Glioblastoma multiforme constitutes the most common and malignant form of primary brain tumor. Median survival for recurrent…”
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Bevacizumab (B), cisplatin (C), and pemetrexed (P) plus maintenance B in chemonaive patients (pts) with advanced nonsquamous non-small cell lung cancer (nsNSCLC): A phase II study
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e18031 Background: B in combination with platinum doublets followed by continuation maintenance with B prolongs survival and delays progression…”
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Nivolumab Induced Acute Severe Toxicity in Lung Adenocarcinoma
Published in The Open cancer immunology journal (26-03-2018)Get full text
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Correlation of increased tumor expression of estrogen receptor alpha mRNA and low aromatase protein ratio with prognosis in resected non-small cell lung cancer (NSCLC)
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e21009 Background: Although several studies have shown the presence of estrogen receptors (ERs) in lung tumors, published reports show…”
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Adjuvant chemotherapy with cisplatin and gemcitabine in resected non-small cell lung cancer: A single institutional experience
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e17522 Background: Adjuvant chemotherapy in operable non small cell lung cancer (NSCLC) has been shown to improve overall survival in many…”
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Bevacizumab plus chemotherapy in the treatment of metastatic breast cancer: Hospital of Cruces experience
Published in Journal of clinical oncology (20-05-2012)“…Abstract only e11525 Background: Antiangiogenic therapies such as bevacizumab (BV), have proven to be effective in improving outcomes in metastatic disease…”
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Paclitaxel for progressive basal cell carcinoma
Published in Journal of the American Academy of Dermatology (01-02-2006)Get full text
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Fixed-Dose-Rate Gemcitabine Infusion in Patients with Advanced Pancreatic or Biliary Tree Adenocarcinoma
Published in Tumori (01-05-2010)“…Aims and background Gemcitabine is an effective agent in pancreatic adenocarcinoma. Fixed-dose-rate gemcitabine has an interesting biological and clinical…”
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Oxaliplatin overdosage successfully recovered with mild toxicities
Published in Acta oncologica (2006)Get more information
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Biweekly administration of cisplatin/gemcitabine in advanced nonsmall cell lung cancer
Published in American journal of clinical oncology (01-10-2005)“…In an attempt to increase the dose intensity of cisplatin and gemcitabine given to patients with stage IIIB or IV nonsmall cell lung cancer without increasing…”
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Prognostic factors in cancer of unknown primary site
Published in Clinical & translational oncology (2008)Get full text
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