Search Results - "Rubio, Elena"

Molecular dynamics simulations reveal the impact of NUDT15 R139C and R139H variants in structural conformation and dynamics by Gómez-Rubio, Elena, Garcia-Marin, Javier

“…NUDT15, also known as MTH2, is a member of the NUDIX protein family that catalyzes the hydrolysis of nucleotides and deoxynucleotides, as well as thioguanine…”
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Non-extractable polyphenols, a major dietary antioxidant: occurrence, metabolic fate and health effects by Pérez-Jiménez, Jara, Díaz-Rubio, M. Elena, Saura-Calixto, Fulgencio

“…Current research on dietary antioxidants misses the so-called non-extractable polyphenols (NEPP), which are not significantly released from the food matrix…”
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Incidence, Clinical Presentation, Relapses and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Patients Treated With Anti-CD20 Monoclonal Antibodies by Calderón-Parra, Jorge, Múñez-Rubio, Elena, Fernández-Cruz, Ana, García-Sánchez, María Cristina, Maderuelo-González, Esther, López-Dosil, Marcos, Calvo-Salvador, Marina, Baños-Pérez, Isolina, Valle-Falcones, Manuel, Ramos-Martínez, Antonio

“…Abstract Background Our objective is to describe the presentation and complications, including relapses, of coronavirus disease 2019 (COVID-19) in patients…”
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iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function by Eade, Kevin T, Ansell, Brendan Robert E, Giles, Sarah, Fallon, Regis, Harkins-Perry, Sarah, Nagasaki, Takayuki, Tzaridis, Simone, Wallace, Martina, Mills, Elizabeth A, Farashi, Samaneh, Johnson, Alec, Sauer, Lydia, Hart, Barbara, Diaz-Rubio, M Elena, Bahlo, Melanie, Metallo, Christian, Allikmets, Rando, Gantner, Marin L, Bernstein, Paul S, Friedlander, Martin

“…Patient-derived induced pluripotent stem cells (iPSCs) provide a powerful tool for identifying cellular and molecular mechanisms of disease. Macular…”
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COVID‐19‐associated pulmonary aspergillosis (CAPA): Risk factors and development of a predictive score for critically ill COVID‐19 patients by Calderón‐Parra, Jorge, Mills‐Sanchez, Patricia, Moreno‐Torres, Victor, Tejado‐Bravo, Sandra, Romero‐Sánchez, Isabel, Balandin‐Moreno, Bárbara, Calvo‐Salvador, Marina, Portero‐Azorín, Francisca, García‐Masedo, Sarela, Muñez‐Rubio, Elena, Ramos‐Martinez, Antonio, Fernández‐Cruz, Ana

“…Background COVID‐19‐associated pulmonary aspergillosis (CAPA) is a major complication of critically ill COVID‐19 patients, with a high mortality rate and…”
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Valacyclovir and Acyclovir Are Substrates of the Guanine Deaminase Cytosolic PSD-95 Interactor (Cypin) by Lange, Keith R, Rasheed, Noor, Su, Xiaoyang, Diaz-Rubio, M Elena, Firestein, Bonnie L

“…Valacyclovir, enzymatically hydrolyzed in the body to acyclovir, is a guanine-based nucleoside analog commonly prescribed as an antiviral therapy. Previous…”
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Red blood cell distribution width as prognostic factor in sepsis: A new use for a classical parameter by Moreno-Torres, Víctor, Royuela, Ana, Múñez-Rubio, Elena, Gutierrez-Rojas, Ángela, Mills-Sánchez, Patricia, Ortega, Alfonso, Tejado-Bravo, Sandra, García-Sanz, Javier, Muñoz-Serrano, Alejandro, Calderón-Parra, Jorge, Fernández-Cruz, Ana, Ramos-Martínez, Antonio

“…To evaluate Red blood cell distribution width (RDW) as a sepsis prognostic biomarker. 203 septic patients admitted to the ICU. Analysis of RDW dynamics,…”
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Contribution of Macromolecular Antioxidants to Dietary Antioxidant Capacity: A Study in the Spanish Mediterranean Diet by Pérez-Jiménez, Jara, Elena Díaz-Rubio, M, Saura-Calixto, Fulgencio

“…Epidemiological and clinical studies show that diets with a high antioxidant capacity, such us those rich in plant food and beverages, are associated with…”
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Gender differences in road traffic injury rate using time travelled as a measure of exposure by Santamariña-Rubio, Elena, Pérez, Katherine, Olabarria, Marta, Novoa, Ana M.

“…•The risk of traffic injuries is higher for men than for women only in some age groups.•There is interaction between gender and age among different type of…”
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Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a randomised controlled trial by Caballero Bermejo, Antonio F, Ruiz-Antorán, Belén, Fernández Cruz, Ana, Diago Sempere, Elena, Callejas Díaz, Alejandro, Múñez Rubio, Elena, Avendaño-Solá, Cristina, Ramos Martínez, Antonio, Sancho López, Aránzazu

“…In some patients, acute, life-threatening respiratory injury produced by viruses such as SARS-CoV and other viral pneumonia are associated with an…”
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Effects of grape antioxidant dietary fiber in cardiovascular disease risk factors by Jiménez, Jara Pérez, Ph.D, Serrano, Jose, Ph.D, Tabernero, Maria, Ph.D, Arranz, Sara, M.D, Díaz-Rubio, M. Elena, Ph.D, García-Diz, Luis, Ph.D, Goñi, Isabel, Ph.D, Saura-Calixto, Fulgencio, Ph.D

“…Abstract Objective The objective of the study was to evaluate the effects of a grape product rich in dietary fiber and natural antioxidants on cardiovascular…”
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Ocular Drug Delivery: A Special Focus on the Thermosensitive Approach by Sapino, Simona, Chirio, Daniela, Peira, Elena, Abellán Rubio, Elena, Brunella, Valentina, Jadhav, Sushilkumar A, Chindamo, Giulia, Gallarate, Marina

“…The bioavailability of ophthalmic therapeutics is reduced because of the presence of physiological barriers whose primary function is to hinder the entry of…”
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Efficacy and safety of antiviral plus anti-spike monoclonal antibody combination therapy vs. monotherapy for high-risk immunocompromised patients with mild-to-moderate SARS-CoV2 infection during the Omicron era: A prospective cohort study by Calderón-Parra, Jorge, Gutiérrez-Villanueva, Andrea, Ronda-Roca, Gerard, Jimenez, Maria Luisa Martín, de la Torre, Helena, Ródenas-Baquero, María, Paniura-Pinedo, María, Lozano-Llano, Carla, Pintos-Pascual, Ilduara, Fernández-Cruz, Ana, Ramos-Martínez, Antonio, Muñez-Rubio, Elena

“…•Prospective cohort study to compare monotherapy vs. combination therapy in immunocompromised patients with COVID-19.•Sotrovimab plus a direct-acting antiviral…”
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Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases by Martin Merinero, Héctor, Subías, Marta, Pereda, Amaia, Gómez-Rubio, Elena, Juana Lopez, Lucia, Fernandez, Constantino, Goicoechea de Jorge, Elena, Martin-Santamaria, Sonsoles, Cañada, Francisco Javier, Rodríguez de Córdoba, Santiago

“…Factor H (FH)–related proteins are a group of partly characterized complement proteins thought to promote complement activation by competing with FH in binding…”
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One-year follow-up of changes in refraction and aberrations induced by corneal incision by Villegas, Eloy A, Alcón, Encarna, Rubio, Elena, Marín, José María, Artal, Pablo

“…To evaluate the surgically induced changes in refraction (sphere and astigmatism) and higher order aberrations by corneal incision for one year. University…”
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A retrospective validation of different scores of guideline adherence and infectious diseases consultation on candidaemia: The higher, the better by Calderón‐Parra, Jorge, Herraiz‐Jiménez, Jesus, Ramos‐Martínez, Antonio, Muñez‐Rubio, Elena, Callejas‐Diaz, Alejandro, Diaz de Santiago, Alberto, Sánchez‐Romero, Isabel, López‐Dosil, Marcos, Fernández‐Cruz, Ana

“…Background Recently, several scores to quantify compliance with the guidelines in candidaemia management (EQUAL, GEMICOMED, Valerio) have been developed…”
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The Right Time for Steroids in COVID-19 by Fernández-Cruz, Ana, Ruiz-Antorán, Belén, Múñez-Rubio, Elena, Sancho-López, Aránzazu, Callejas-Díaz, Alejandro, Avendaño-Solá, Cristina, Ramos-Martínez, Antonio

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COVID-19 in hospitalized solid organ transplant recipients in a nationwide registry study by Moreno-Torres, Víctor, Martínez-Urbistondo, María, Calderón-Parra, Jorge, Mills, Patricia, Muñoz-Serrano, Alejandro, Arias-Milla, Ana, Benítez, Laura, Aguilar-Pérez, Myriam, Múñez-Rubio, Elena, Ramos-Martínez, Antonio, Fernández-Cruz, Ana, Cuervas-Mons, Valentín, de Mendoza, Carmen

“…•Solid organ transplant recipients had similar mortality to other patients.•Age, male gender, and lymphoma were risk factors for mortality among solid organ…”
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Untargeted metabolomic profiles reveal widespread metabolic perturbations and identify candidate biomarkers in aminoaciduric canine hypoaminoacidemic hepatopathy syndrome by Loftus, John P., Rubio, M. Elena Diaz, Yant, Jillian, Bichoupan, Allison, Zhang, Sheng, Miller, Adam J., Center, Sharon A., Ruiz, Maria D. R., Macho, Luis P.

“…OBJECTIVETo identify metabolites and metabolic pathways affected in dogs with aminoaciduric canine hypoaminoacidemic hepatopathy syndrome (ACHES) compared to…”
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Updated methodology to determine antioxidant capacity in plant foods, oils and beverages: Extraction, measurement and expression of results by Pérez-Jiménez, Jara, Arranz, Sara, Tabernero, Maria, Díaz- Rubio, M. Elena, Serrano, José, Goñi, Isabel, Saura-Calixto, Fulgencio

“…The comparison between antioxidant capacity values reported by different laboratories is quite difficult because of substantial differences in sample…”
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