Search Results - "Rubio, Débora"

VDR, SOD-2, and CYP24A1 Gene Expression in Different Genotypes of BsmI SNP of the Vitamin D Receptor Gene in Individuals with Hypovitaminosis by Retamoso, Vanessa Rosa, Barbisan, Fernanda, Moro, Graziele Meira, Maurer, Patricia, Rubio, Débora Vasquez, Dos Santos, Lauren Flores Viera, Feijóo, Lyana Berro, Frizzo, Matias Nunes, Mânica da Cruz, Ivana Beatrice, Manfredini, Vanusa, Barcelos, Ana Letícia Vargas, Piccoli, Jacqueline da Costa Escobar

“…Hypovitaminosis D is a public health problem due to its implications for various diseases. Vitamin D has numerous functions, such as modulating the metabolism…”
Get full text

Black skin color but not VDR gene represent a risk factor for low serum levels of vitamin D in self-declared black individuals by Retamoso, Vanessa Rosa, Feijóo, Lyana Berro, Vasquez Rubio, Débora Alejandra, dos Santos, Lauren Alicia Flores Viera, Vargas Barcelos, Ana Leticia, Piccoli, Jacqueline da Costa Escobar

“…The absorption of vitamin D occurs via two main pathways: first, through the biosynthesis in the skin under the exposure of UV from sunlight; and second,…”
Get full text

Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae by Lomovskaya, Olga, Sun, Dongxu, Rubio-Aparicio, Debora, Nelson, Kirk, Tsivkovski, Ruslan, Griffith, David C, Dudley, Michael N

“…Vaborbactam (formerly RPX7009) is a new beta-lactamase inhibitor based on a cyclic boronic acid pharmacophore. The spectrum of beta-lactamase inhibition by…”
Get full text

Glomerulonefritis por cambios mínimos post vacuna COVID-19 AstraZeneca by Pérez De Pedro, Fernando, Ernesto Caliva, Belén Faría, Rubio, Débora, Lotti, Alejandro

“…We report a case of a 28-year-old woman with minimal change disease secondary nephrotic syndrome 48 hours after the administration of the AstraZeneca SARS-CoV2…”
Get full text

The Val16Ala MnSOD gene polymorphism is associated with hypertension in self-declared black individuals by Berro, Lyana Feijoó, Maurer, Patricia, Rubio, Debora, Retamoso, Vanessa, Santos, Lauren, Manfredini, Vanusa, Piccoli, Jacqueline da Costa Escobar

“…Hypertension is the leading contributor to cardiovascular disease worldwide; the prevalence of hypertension is higher among black adults than other…”
Get more information

Evolución de la función renal en pacientes con enfermedad renal crónica con dieta restringida en proteínas suplementada con una mezcla de aminoácidos y cetoanálogos by Aimar, María Andrea, Pomiglio, Gabriela, Baccaro, Fernando, Traverso, Mario, Audisio, Jorge, De Feo, Priscila, Crivelli, Adriana, Flores Lazdin, Mariela

“…Introducción: la enfermedad renal crónica (ERC) es un problema de salud pública. Se ha evaluado el uso de dietas con bajo contenido proteico suplementadas con…”
Get full text

Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae by Sun, Dongxu, Rubio-Aparicio, Debora, Nelson, Kirk, Dudley, Michael N, Lomovskaya, Olga

“…Vaborbactam (formerly RPX7009) is a new β-lactamase inhibitor based on a cyclic boronic acid pharmacophore with potent inhibitory activity against…”
Get full text

In Vitro Activity of the Ultrabroad-Spectrum-Beta-Lactamase Inhibitor QPX7728 against Carbapenem-Resistant Enterobacterales with Varying Intrinsic and Acquired Resistance Mechanisms by Nelson, Kirk, Rubio-Aparicio, Debora, Sun, Dongxu, Dudley, Michael, Lomovskaya, Olga

“…QPX7728 is an investigational ultrabroad-spectrum-beta-lactamase inhibitor (BLI) with potent inhibition of key serine and metallo-beta-lactamases. QPX7728…”
Get full text

Intrinsic Antibacterial Activity of Xeruborbactam In Vitro: Assessing Spectrum and Mode of Action by Sun, Dongxu, Tsivkovski, Ruslan, Pogliano, Joe, Tsunemoto, Hannah, Nelson, Kirk, Rubio-Aparicio, Debora, Lomovskaya, Olga

“…Xeruborbactam (formerly QPX7728) is a cyclic boronate inhibitor of numerous serine and metallo-beta-lactamases. At concentrations generally higher than those…”
Get full text

Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases: Enhancement of Activity of Multiple Antibiotics against Isogenic Strains Expressing Single Beta-Lactamases by Lomovskaya, Olga, Tsivkovski, Ruslan, Nelson, Kirk, Rubio-Aparicio, Debora, Sun, Dongxu, Totrov, Maxim, Dudley, Michael N

“…QPX7728 is an ultrabroad-spectrum boronic acid beta-lactamase inhibitor, with potent inhibition of key serine and metallo-beta-lactamases being observed in…”
Get full text

The Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 Restores the Potency of Multiple Oral Beta-Lactam Antibiotics against Beta-Lactamase-Producing Strains of Resistant Enterobacterales by Lomovskaya, Olga, Rubio-Aparicio, Debora, Tsivkovski, Ruslan, Loutit, Jeff, Dudley, Michael

“…QPX7728 is a cyclic boronate ultrabroad-spectrum beta-lactamase inhibitor, with potent activity against both serine beta-lactamases and…”
Get full text

Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases by Hecker, Scott J, Reddy, K. Raja, Lomovskaya, Olga, Griffith, David C, Rubio-Aparicio, Debora, Nelson, Kirk, Tsivkovski, Ruslan, Sun, Dongxu, Sabet, Mojgan, Tarazi, Ziad, Parkinson, Jonathan, Totrov, Maxim, Boyer, Serge H, Glinka, Tomasz W, Pemberton, Orville A, Chen, Yu, Dudley, Michael N

“…Despite major advances in the β-lactamase inhibitor field, certain enzymes remain refractory to inhibition by agents recently introduced. Most important among…”
Get full text

Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases in Enterobacteriaceae , Pseudomonas aeruginosa, and Acinetobacter baumannii by Lomovskaya, Olga, Nelson, Kirk, Rubio-Aparicio, Debora, Tsivkovski, Ruslan, Sun, Dongxu, Dudley, Michael N

“…QPX7728 is an ultrabroad-spectrum boronic acid beta-lactamase inhibitor that demonstrates inhibition of key serine and metallo-beta-lactamases at a nanomolar…”
Get full text

Resistance to Ceftazidime-Avibactam Is Due to Transposition of KPC in a Porin-Deficient Strain of Klebsiella pneumoniae with Increased Efflux Activity by Nelson, Kirk, Hemarajata, Peera, Sun, Dongxu, Rubio-Aparicio, Debora, Tsivkovski, Ruslan, Yang, Shangxin, Sebra, Robert, Kasarskis, Andrew, Nguyen, Hoan, Hanson, Blake M, Leopold, Shana, Weinstock, George, Lomovskaya, Olga, Humphries, Romney M

“…Ceftazidime-avibactam is an antibiotic with activity against serine beta-lactamases, including carbapenemase (KPC). Recently, reports have emerged of…”
Get full text

In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa by Lomovskaya, Olga, Rubio-Aparicio, Debora, Nelson, Kirk, Sun, Dongxu, Tsivkovski, Ruslan, Castanheira, Mariana, Lindley, Jill, Loutit, Jeffery, Dudley, Michael

“…QPX7728 is an ultrabroad-spectrum beta-lactamase inhibitor with potent inhibition of key serine and metallo beta-lactamases. QPX7728 enhances the potency of…”
Get full text

In Vitro Activity of the Ultra-Broad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Meropenem against Clinical Isolates of Carbapenem-Resistant Acinetobacter baumannii by Nelson, Kirk, Rubio-Aparicio, Debora, Tsivkovski, Ruslan, Sun, Dongxu, Totrov, Maxim, Dudley, Michael, Lomovskaya, Olga

“…QPX7728 is a recently discovered ultra-broad-spectrum beta-lactamase inhibitor (BLI) with potent inhibition of key serine and metallo-beta-lactamases. QPX7728…”
Get full text

In vitro potency of xeruborbactam in combination with multiple β-lactam antibiotics in comparison with other β-lactam/β-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum β-lactamase-producing Enterobacterales by Lomovskaya, Olga, Castanheira, Mariana, Lindley, Jill, Rubio-Aparicio, Debora, Nelson, Kirk, Tsivkovski, Ruslan, Sun, Dongxu, Totrov, Maxim, Loutit, Jeffery, Dudley, Michael

“…Recently, several β-lactam (BL)/β-lactamase inhibitor (BLI) combinations have entered clinical testing or have been marketed for use, but limited direct…”
Get full text

Potency of Meropenem-Vaborbactam in Lung Surfactant by Rubio-Aparicio, Debora, Loutit, Jeff, Dudley, Michael, Lomovskaya, Olga

“…This study investigated whether pulmonary surfactant has an effect on the antibacterial activity of either meropenem alone or meropenem in combination with…”
Get full text

Development and Implementation of a Verification Protocol for Regulatory Compliance of Electrical Systems in Critical Hospital Areas by Santoni, Diego Nicolas, Blume, Mario Orlando, Rubio, Debora, Conte, Federico, Ponce, Sergio D

“…Electrical safety in critical hospital areas is paramount for protecting patients, medical personnel, and biomedical equipment. This work presents a…”
Get full text

Activity of Meropenem-Vaborbactam in Mouse Models of Infection Due to KPC-Producing Carbapenem-Resistant Enterobacteriaceae by Sabet, Mojgan, Tarazi, Ziad, Nolan, Thomas, Parkinson, Jonathan, Rubio-Aparicio, Debora, Lomovskaya, Olga, Dudley, Michael N, Griffith, David C

“…Meropenem-vaborbactam (Vabomere) is highly active against Gram-negative pathogens, especially carbapenemase (KPC)-producing, carbapenem-resistant The objective…”
Get full text