Search Results - "Rubio, Andres J."
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Proteasome 26S subunit, non-ATPases 1 (PSMD1) and 3 (PSMD3), play an oncogenic role in chronic myeloid leukemia by stabilizing nuclear factor-kappa B
Published in Oncogene (15-04-2021)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 have revolutionized therapy for chronic myeloid leukemia (CML), paving the way for clinical development in…”
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19S Proteasome Subunits as Oncogenes and Prognostic Biomarkers in FLT3-Mutated Acute Myeloid Leukemia (AML)
Published in International journal of molecular sciences (23-11-2022)“…26S proteasome non-ATPase subunits 1 (PSMD1) and 3 (PSMD3) were recently identified as prognostic biomarkers and potential therapeutic targets in chronic…”
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26S Proteasome Non-ATPase Regulatory Subunits 1 (PSMD1) and 3 (PSMD3) as Putative Targets for Cancer Prognosis and Therapy
Published in Cells (Basel, Switzerland) (11-09-2021)“…Ever since the ubiquitin proteasome system was characterized, efforts have been made to manipulate its function to abrogate the progression of cancer. As a…”
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The prognostic value of 19S ATPase proteasome subunits in acute myeloid leukemia and other forms of cancer
Published in Frontiers in medicine (12-07-2023)“…The ubiquitin-proteasome system (UPS) is an intracellular organelle responsible for targeted protein degradation, which represents a standard therapeutic…”
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Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism
Published in Clinical and translational medicine (01-12-2022)“…Tyrosine kinase inhibitors (TKIs) targeting BCR::ABL1 have turned chronic myeloid leukaemia (CML) from a fatal disease into a manageable condition for most…”
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Energy metabolism and drug response in myeloid leukaemic stem cells
Published in British journal of haematology (01-08-2019)“…Summary Despite significant advances in the treatment of myeloid malignancies, many patients become resistant to therapy and ultimately succumb to their…”
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Ethnic and border differences on blood cancer presentation and outcomes: A Texas population‐based study
Published in Cancer (01-04-2021)“…Background The Texas/Chihuahua (US/Mexico) border is a medically underserved region with many reported barriers for health care access. Although Hispanic…”
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Large Peritoneal Macrophages and Transitional Premonocytes Promote Survival during Abdominal Sepsis
Published in ImmunoHorizons (29-12-2021)“…Monocytes and macrophages are early sentinels of infection. The peritoneum contains two resident populations: large and small peritoneal macrophages (LPMs and…”
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Blood cancer health disparities in the United States Hispanic population
Published in Cold Spring Harbor molecular case studies (01-04-2021)“…Cancer is a challenging, multifaceted disease that involves a combination of biological and nonbiological factors. Aside from COVID-19, cancer is the second…”
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Abstract P150: PSMD1 and PSMD3 as putative targets for cancer therapy
Published in Molecular cancer therapeutics (01-12-2021)“…Ever since the ubiquitin proteasome system was characterized, efforts have been made to manipulate its function to abrogate the progression of cancer. As a…”
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Regulation of Oxidative Energy Metabolism By G0S2 in FLT3+ AML
Published in Blood (15-11-2022)Get full text
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19S Proteasome Subunits As Oncogenes and Prognostic Biomarkers in FLT3-Mutated Acute Myeloid Leukemia (AML)
Published in Blood (15-11-2022)Get full text
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Abstract 647: NF-kB associates with tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 are effective at eliminating most BCR-ABL1+ cells in chronic myeloid leukemia (CML), but do not target CML…”
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Abstract 4343: Retrospective study of incidence and survival for patients with hematological malignancies residing at the U.S./Mexico border
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Introduction: Hispanics represent the largest minority group in the United States (U.S.), with 57.5 million individuals. The majority of Hispanics in the U.S…”
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Abstract 648: Role of G0S2 in chronic myeloid leukemia and TKI resistance
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 have turned chronic myeloid leukemia (CML) from a fatal to a chronic disease. However, resistance is a…”
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Proteasome 26S subunit, non-ATPases 1 , play an oncogenic role in chronic myeloid leukemia by stabilizing nuclear factor-kappa B
Published in Oncogene (15-04-2021)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 have revolutionized therapy for chronic myeloid leukemia (CML), paving the way for clinical development in…”
Get full text
Journal Article -
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NF-κB-Dependent Activation of the Proteasome Components, PSMD1 and PSMD3, As a Mechanism of Resistance to Imatinib
Published in Blood (13-11-2019)“…Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 are remarkably effective therapies in chronic myeloid leukemia (CML). Despite clinical success, TKIs do…”
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Retrospective Study of Incidence and Survival for Patients with Hematologic Malignancies Residing at the U.S./Mexico Border
Published in Blood (13-11-2019)“…Introduction: Hispanics represent the largest minority group in the United States (U.S.), with 57.5 million individuals (18% of the population). Most U.S…”
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Strain-induced band gap engineering in layered TiS3
Published in Nano research (2018)“…By combining ab initio calculations and experiments, we demonstrate how the band gap of the transition metal trichalcogenide TiS3 can be modified by inducing…”
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