Search Results - "Rubinstein, WS"

Effect of a Computer-Based Decision Aid on Knowledge, Perceptions, and Intentions About Genetic Testing for Breast Cancer Susceptibility: A Randomized Controlled Trial by Green, Michael J, Peterson, Susan K, Baker, Maria Wagner, Harper, Gregory R, Friedman, Lois C, Rubinstein, Wendy S, Mauger, David T

“…CONTEXT As the availability of and demand for genetic testing for hereditary cancers increases in primary care and other clinical settings, alternative or…”
Get full text

Hereditary Diffuse Gastric Cancer : Diagnosis, Genetic Counseling, and Prophylactic Total Gastrectomy by LYNCH, Henry T, KAURAH, Pardeep, WIRTZFELD, Debrah, RUBINSTEIN, Wendy S, WEISSMAN, Scott, LYNCH, Jane F, GRADY, William, WIYRICK, Sara, SENZ, Janine, HUNTSMAN, David G

“…A subset of patients with diffuse gastric cancer harbor deleterious cancer-causing germline mutations in the type 1 E-cadherin (epithelial) gene (CDH1), which…”
Get full text

BRCAPRO Validation, Sensitivity of Genetic Testing of BRCA1/BRCA2, and Prevalence of Other Breast Cancer Susceptibility Genes by BERRY, Donald A, IVERSEN, Edwin S, RUBINSTEIN, Wendy S, HUGHES, Kevin S, PARMIGIANI, Giovanni, GUDBJARTSSON, Daniel F, HILLER, Elaine H, GARBER, Judy E, PESHKIN, Beth N, LERMAN, Caryn, WATSON, Patrice, LYNCH, Henry T, HILSENBECK, Susan G

“…To compare genetic test results for deleterious mutations of BRCA1 and BRCA2 with estimated probabilities of carrying such mutations; to assess sensitivity of…”
Get full text

Mutations in SDHD, A Mitochondrial Complex II Gene, in Hereditary Paraganglioma by Baysal, Bora E., Ferrell, Robert E., Willett-Brozick, Joan E., Lawrence, Elizabeth C., Myssiorek, David, Bosch, Anne, van der Mey, Andel, Peter E. M. Taschner, Rubinstein, Wendy S., Myers, Eugene N., Richard, Charles W., Cornelisse, Cees J., Devilee, Peter, Devlin, B.

“…Hereditary paraganglioma (PGL) is characterized by the development of benign, vascularized tumors in the head and neck. The most common tumor site is the…”
Get full text

Prevalence of SDHB, SDHC, and SDHD germline mutations in clinic patients with head and neck paragangliomas by Baysal, B E, Willett-Brozick, J E, Lawrence, E C, Drovdlic, C M, Savul, S A, McLeod, D R, Yee, H A, Brackmann, D E, Slattery, W H, Myers, E N, Ferrell, R E, Rubinstein, W S

“…Background: Paragangliomas are rare and highly heritable tumours of neuroectodermal origin that often develop in the head and neck region. Germline mutations…”
Get full text

Surgical management of BRCA1 and BRCA2 carriers: bitter choices slightly sweetened by Rubinstein, Wendy S

Get full text

TGFBR16A and Cancer Risk: A Meta-Analysis of Seven Case-Control Studies by Kaklamani, Virginia G, Hou, Nanjiang, Bian, Yiansong, Reich, Jennifer, Offit, Kenneth, Michel, Loren S, Rubinstein, W S, Rademaker, Alfred, Pasche, Boris

“…TGFBR1*6A is a hypomorphic polymorphic allele of the type I transforming growth factor beta receptor (TGFBR1). TGFBR1*6A is a candidate tumor susceptibility…”
Get full text

Use of an educational computer program before genetic counseling for breast cancer susceptibility: Effects on duration and content of counseling sessions by Green, Michael J., Peterson, Susan K., Baker, Maria Wagner, Friedman, Lois C., Harper, Gregory R., Rubinstein, Wendy S., Peters, June A., Mauger, David T.

“…Patients seeking genetic testing for inherited breast cancer risk are typically educated by genetic counselors; however, the growing demand for cancer genetic…”
Get full text

Hereditary nonpolyposis colorectal carcinoma (HNPCC) and HNPCC‐like families: Problems in diagnosis, surveillance, and management by Lynch, Henry T., Riley, Bronson D., Weismann, Scott, Coronel, Stephanie M., Kinarsky, Yulia, Lynch, Jane F., Shaw, Trudy G., Rubinstein, Wendy S.

“…BACKGROUND To the authors' knowledge, hereditary nonpolyposis colorectal carcinoma (HNPCC) is the most commonly occurring hereditary disorder that predisposes…”
Get full text

Phenotypic dichotomy in mitochondrial complex II genetic disorders by BAYSAL, Bora E, RUBINSTEIN, Wendy S, TASCHNER, Peter E. M

“…This review presents our current knowledge on the genetic and phenotypic aspects of mitochondrial complex II gene defects. The mutations of the complex II…”
Get full text

Hereditary Breast-Ovarian Cancer at the Bedside: Role of the Medical Oncologist by LYNCH, Henry T, SNYDER, Carrie L, LYNCH, Jane F, RILEY, Bronson D, RUBINSTEIN, Wendy S

“…To provide practical considerations for diagnosing, counseling, and managing patients at high risk for hereditary breast cancer. We have studied 98 extended…”
Get full text

Proportion of Heritable Paraganglioma Cases and Associated Clinical Characteristics by Drovdlic, Carrie M., Myers, Eugene N., Peters, June A., Baysal, Bora E., Brackmann, Derald E., Slattery III, William H., Rubinstein, Wendy S.

“…Objective/Hypothesis To determine the heritable proportion of paraganglioma (PGL) and identify clinical features associated with heritable PGL. Study Design…”
Get full text

Transplantation of human hepatocytes by Strom, S C, Fisher, R A, Rubinstein, W S, Barranger, J A, Towbin, R B, Charron, M, Mieles, L, Pisarov, L A, Dorko, K, Thompson, M T, Reyes, J

Get full text

Prophylactic Mastectomy: Obstacles and Benefits by Lynch, Henry T., Lynch, Jane F., Rubinstein, Wendy S.

“…Onlytime will tell!REFERENCES(1) Hartmann LC, Sellers TA, Schaid DJ, Frank TS, Soderberg CL, Sitta DL,et al. Efficacyof bilateral prophylactic mastectomyin…”
Get full text

Fine mapping of an imprinted gene for familial nonchromaffin paragangliomas, on chromosome 11q23 by BAYSAL, B. E, FARR, J. E, MYSSIOREK, D, SINGH, D, SAHA, S, GOLLIN, S. M, EVANS, G. A, JAMES, M. R, RICHARD, C. W, RUBINSTEIN, W. S, GALUS, R. A, JOHNSON, K. A, ASTON, C. E, MYERS, E. N, JOHNSON, J. T, CARRAU, R, KIRKPATRICK, S. J

“…Hereditary nonchromaffin paragangliomas (PGL; glomus tumors; MIM 168000) are mostly benign, slow-growing tumors of the head and neck region, inherited from…”
Get full text

Repositioning the hereditary paraganglioma critical region on chromosome band 11q23 by BAYSAL, B. E, VAN SCHOTHORST, E. M, RICHARD, C. W, FARR, J. E, GRASHOF, P, MYSSIOREK, D, RUBINSTEIN, W. S, TASCHNER, P, CORNELISSE, C. J, DEVLIN, B, DEVILEE, P

“…Hereditary paragangliomas (PGL, glomus tumors, MIM no.168000) are mostly benign, slow-growing tumors of the head and neck region. The gene (or genes) affecting…”
Get full text

Computer-Based Genetic Counseling by Rubinstein, Wendy S

Get full text

Haploinsufficiency for BRCA1 is associated with normal levels of DNA nucleotide excision repair in breast tissue and blood lymphocytes by Latimer, Jean J, Rubinstein, Wendy S, Johnson, Jennifer M, Kanbour-Shakir, Amal, Vogel, Victor G, Grant, Stephen G

“…Screening mammography has had a positive impact on breast cancer mortality but cannot detect all breast tumors. In a small study, we confirmed that low power…”
Get full text

The Genetics of Sudden Death by Rubenstein, Wendy S, Lopez-Soler, Reynold I

“…Rubinstein and Lopez-Soler explore the heterogeneous genetic causes of sudden cardiac death (SCD). If genetic etiology plays an important role in SCD due to…”
Get full text

A 'Normal' Practice by Rubinstein, Wendy S

“…Rubinstein defends the "normalcy" of practicing medical genetics…”
Get full text